RetrogeneDB ID: retro_cjac_282

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 11:116798823..116799714(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCJAG00000021865
• Aliases: None
• Status: KNOWN_PROTEIN_CODING

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCJAG00000007018
• Aliases: None
• Description: Malate dehydrogenase [Source:UniProtKB/TrEMBL;Acc:F6YJ68]

Sequence

>retro_cjac_282
ATGTCCGAACAAATCAGAGTCCCTGTGACTGGAGCAGCTGGTCAGATTGCATATTCATTGCTGTACAGTATTGGAAATGG
ATCTGTCTTTGGTAAAGACCAGCCTGTAATTCTTATGCTGTTGGATACCACCCCCATGATGGGTGTCCTGGATGGTGTCC
TAATGGAACTTCAAGACTGTGCCCTTCCCCTCCTGAAAGATGTCATCGCAACAGATAAAGAAGAGGTTGCCTTCAAAGAC
CTGGATGTGGCCATTCTCGTAGGCTCCATGCCAAGAAGGGAGGGCATGGAGAGAAAAGATTTACTGAAAGCAAACGTGAA
AATCTTCAAATCCCAGGGTGCAGCCTTGGATAAATACGCAAAGAAGTCAGTTAAGGTTATTGTTGTGGGTAATCCAGCCA
ATACCAACTGCCTGACTGCCTCCAAGTCAGCTCCATCCATCCCCAAGGAGAACTTCAGTTGCTTGACCCGTTTGGATCAC
AACCGAGCTAAAGCTCAAATTGCTCTTAAACTTGGTGTGACTGCTAATGATGTAAAGAATGTCATTATCTGGGGAAACCG
TTCCTCAACTCAGTATCCAGATGTCAACCATGCCAAGGTGAAATTGCAAGGAAAGGAAGTTGGTGTTTATGAAGCTCTGA
AAGATGACAACTGGCTCAAGGGAGAATTTGTCACAGGAGAGTTTGTGTCCATGGGTGTTATCTCTGATGGCAATTCCTAT
GGTGTTCCTGATGATCTGCTCTACTCATTCCCTGTTGTAATCAAGAATAAGACCTGGAAGTTCGTTGAAGGTCTCCCTAT
TAATGATTTCTCACGTGAGAAGATGGATCTTACTGCAAAGGAGCTGACAGAAGAAAAAGAAACTGCTTTTGAATTTCTTT
CCTCTGCCTGA

Alignment

ORF - retro_cjac_282 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 97.33 %
• Parental protein coverage: 67.57 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MSEPIRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLLKDVIA
          MSE.IRV.VTGAAGQIAYSLLYSIGNGSVFGKDQP.IL.LLD.TPMMGVLDGVLMELQDCALPLLKDVIA
Retrocopy MSEQIRVPVTGAAGQIAYSLLYSIGNGSVFGKDQPVILMLLDTTPMMGVLDGVLMELQDCALPLLKDVIA

Parental  TDKEEVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTA
          TDKEEVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTA
Retrocopy TDKEEVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVKVIVVGNPANTNCLTA

Parental  SKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNHSSTQYPDVNHAKVKLQGKEVGVY
          SKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGN.SSTQYPDVNHAKVKLQGKEVGVY
Retrocopy SKSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTANDVKNVIIWGNRSSTQYPDVNHAKVKLQGKEVGVY

Parental  EALKDDNWLKGEFVT
          EALKDDNWLKGEFVT
Retrocopy EALKDDNWLKGEFVT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.18 RPM	51.43 RPM
SRP051959_heart	0.47 RPM	198.01 RPM
SRP051959_kidney	0.18 RPM	89.12 RPM
SRP051959_liver	0.15 RPM	68.53 RPM
SRP051959_lung	0.11 RPM	21.81 RPM
SRP051959_lymph_node	0.09 RPM	26.09 RPM
SRP051959_skeletal_muscle	0.59 RPM	157.47 RPM
SRP051959_spleen	0.13 RPM	30.57 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_282 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_282 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_282 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 26 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000019295	1 retrocopy	retro_btau_466,
Choloepus hoffmanni	ENSCHOG00000007281	5 retrocopies	retro_chof_1260, retro_chof_1513, retro_chof_1892, retro_chof_2001, retro_chof_90,
Callithrix jacchus	ENSCJAG00000007018	4 retrocopies	retro_cjac_1848, retro_cjac_2407, retro_cjac_2418, retro_cjac_282 ,
Dasypus novemcinctus	ENSDNOG00000013329	2 retrocopies	retro_dnov_109, retro_dnov_2562,
Homo sapiens	ENSG00000014641	1 retrocopy	retro_hsap_3426,
Gorilla gorilla	ENSGGOG00000007085	1 retrocopy	retro_ggor_2316,
Loxodonta africana	ENSLAFG00000016504	2 retrocopies	retro_lafr_1134, retro_lafr_972,
Macaca mulatta	ENSMMUG00000006163	2 retrocopies	retro_mmul_1750, retro_mmul_2496,
Nomascus leucogenys	ENSNLEG00000009823	1 retrocopy	retro_nleu_1363,
Otolemur garnettii	ENSOGAG00000014487	1 retrocopy	retro_ogar_741,
Pongo abelii	ENSPPYG00000012373	1 retrocopy	retro_pabe_2839,
Pan troglodytes	ENSPTRG00000011974	1 retrocopy	retro_ptro_2326,
Sorex araneus	ENSSARG00000007690	1 retrocopy	retro_sara_361,
Sus scrofa	ENSSSCG00000025751	1 retrocopy	retro_sscr_779,
Tarsius syrichta	ENSTSYG00000001215	2 retrocopies	retro_tsyr_1790, retro_tsyr_190,