RetrogeneDB ID: retro_cjac_1486

Retrocopy location

• Organism: Marmoset (Callithrix jacchus)
• Coordinates: 16:92768980..92769670(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PDCL3
• Ensembl ID: ENSCJAG00000010160
• Aliases: None
• Description: phosducin-like 3 [Source:HGNC Symbol;Acc:28860]

Sequence

>retro_cjac_1486
TGGAATTACATCTTATGCAAAAAAGGCATCTCACCCCACAAGGAAAATCTGAAAGAATTGGAAGAGGAGGCAGAAGGGGA
TCAGTGTATCCTCCAGCAGTCAGTGATGACAACATATGAAGATATGACTTTGGGAGAGCTGGAGGATTATGAAGATGAGT
TTAATGAGGAGGATGAACGTGCTATTGAAATATACAGATGGCAGAGACTGGCTGAGTGGAAAGCAACTAAGCTGTAGAAT
ATATTTGGAGAAATTTTGGAGATCTCAGGGAAGCACTATGTTCAAGAAGTTACCAAAGCCGGTGAGGGCTTGTGGGTCAG
CTTGCACCTTTACAAACAAGGAATTCCCCTCTGTGCCCTGATAAAACCGCACCTCAGCGGACTTGCCAGTAAGTTTCCTG
ATGTCAAATTTATCAAAGTCATTTCAACAACCTGAATGCCCAGTTATCCTGAAAGGAATCTGCCTGCGATATTTCTTTAC
CTGGAAGGAGATATCAAATTTCAGTTGATCGATCCTCTGGTGTTTGGTGGCGTGAACCTAACGAGAGATGAGCTGGAGTG
GAAACTGTCTGAATCTGGAACAATTAAGACGAACCTGGAGGAAAACCCTAAGAAGCTGGTTGAAGACGTGTTGCTGTCCT
CAGCGCTGCACTCTGTCCCCAGGAGGAGGGACAGTGATTCTGAGGGTGAC

Alignment

ORF - retro_cjac_1486 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 80.43 %
• Parental protein coverage: 96.23 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  WNDILRKKGILPPKESLKELEEEAEEEQHMVQQSVVTTYEDMTLEELKDHEDEFNEEDERAIEMYRRQRL
          WN.IL.KKGI.P.KE.LKELEEEAE..Q...QQSV.TTYEDMTL.EL.D.EDEFNEEDERAIE.YR.QRL
Retrocopy WNYILCKKGISPHKENLKELEEEAEGDQCILQQSVMTTYEDMTLGELEDYEDEFNEEDERAIEIYRWQRL

Parental  AEWKATKLKNKFGEVLEISGKDYVQEVTKAGEGLWVILHLYKQGIPLCALINQHLSGLASKFPDVKFIKA
          AEWKATKL.N.FGE.LEISGK.YVQEVTKAGEGLWV.LHLYKQGIPLCALI..HLSGLASKFPDVKFIK.
Retrocopy AEWKATKL*NIFGEILEISGKHYVQEVTKAGEGLWVSLHLYKQGIPLCALIKPHLSGLASKFPDVKFIKV

Parental  ISTTCIPNYPDRNLPTIFVYLEGDIKAQFIGPLVFGGMNLTRDELEWKLSESGAVKTDLEENPKKQIEDV
          ISTT..P.YP.RNLP.IF.YLEGDIK.Q.I.PLVFGG.NLTRDELEWKLSESG..KT.LEENPKK..EDV
Retrocopy ISTT*MPSYPERNLPAIFLYLEGDIKFQLIDPLVFGGVNLTRDELEWKLSESGTIKTNLEENPKKLVEDV

Parental  LLSSVRRSVPTWRDSDSDGD
          LLSS...SVP..RDSDS.GD
Retrocopy LLSSALHSVPRRRDSDSEGD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP051959_colon	0.20 RPM	10.38 RPM
SRP051959_heart	0.60 RPM	14.07 RPM
SRP051959_kidney	0.31 RPM	14.22 RPM
SRP051959_liver	0.17 RPM	4.14 RPM
SRP051959_lung	0.96 RPM	8.90 RPM
SRP051959_lymph_node	0.84 RPM	6.89 RPM
SRP051959_skeletal_muscle	0.26 RPM	8.95 RPM
SRP051959_spleen	0.82 RPM	8.07 RPM

ChIP-Seq

Callithrix jacchus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cjac_1486 retrocopy.

TSS

Callithrix jacchus was not studied using FANTOM5 data.

Lab

retro_cjac_1486 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cjac_1486 has 2 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4102
Pan troglodytes	retro_ptro_2784

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Parental genes homology:

Parental genes homology involve 13 parental genes, and 31 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000002226	1 retrocopy	retro_cfam_1740,
Callithrix jacchus	ENSCJAG00000010160	3 retrocopies	retro_cjac_1486 , retro_cjac_1599, retro_cjac_2055,
Dipodomys ordii	ENSDORG00000012397	1 retrocopy	retro_dord_702,
Erinaceus europaeus	ENSEEUG00000000224	1 retrocopy	retro_eeur_506,
Homo sapiens	ENSG00000115539	7 retrocopies	retro_hsap_1132, retro_hsap_151, retro_hsap_2684, retro_hsap_2757, retro_hsap_3535, retro_hsap_3961, retro_hsap_4102,
Myotis lucifugus	ENSMLUG00000016446	1 retrocopy	retro_mluc_1443,
Monodelphis domestica	ENSMODG00000001489	1 retrocopy	retro_mdom_734,
Mus musculus	ENSMUSG00000026078	1 retrocopy	retro_mmus_2284,
Nomascus leucogenys	ENSNLEG00000014393	8 retrocopies	retro_nleu_1499, retro_nleu_1575, retro_nleu_2741, retro_nleu_2891, retro_nleu_538, retro_nleu_571, retro_nleu_778, retro_nleu_926,
Oryctolagus cuniculus	ENSOCUG00000001469	2 retrocopies	retro_ocun_1035, retro_ocun_920,
Otolemur garnettii	ENSOGAG00000015138	2 retrocopies	retro_ogar_1147, retro_ogar_2959,
Ochotona princeps	ENSOPRG00000011600	2 retrocopies	retro_opri_1070, retro_opri_289,
Tursiops truncatus	ENSTTRG00000006242	1 retrocopy	retro_ttru_1184,