RetrogeneDB ID: retro_chof_2574

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_86939:5886..6690(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HNRNPA2B1
• Ensembl ID: ENSCHOG00000013832
• Aliases: None
• Description: heterogeneous nuclear ribonucleoprotein A2/B1 [Source:HGNC Symbol;Acc:5033]

Sequence

>retro_chof_2574
AAGGAATCAGAGCAGTTGAGAAAATTGTTTACTGGTGGTCTGAGCTCTGAAACTATGGATGATAGTTTAGAAGAACACTG
TGAGAAATGAAGCACACTCACAGATTGTATGGTGATGAGAGACCCCCAAACAAAATGTTCCAGAAGCTTTGGTTTTGTTA
CTTACTCTTGTGTTGAAGAGGTGGGTGCAGCAATGTGTGCTTGACTGCACAAGGTTGATGGGTGTGTAGAGGAACCAAAG
AGAGTTGCTCTAGAGAAGATTCTGTAAAGCCTGGTGCCCCTCTAACAGTGAAGAAAAAACTTTTGTTGGTGGTATTAAAG
GAGATACAGAAGAATATAATTTGAGACACTACTTTGAAAAGTCTAGCAAGACTGAAGCCAAAGAAGTTACGGAAGACAGA
CAGAGTGGGAAAAAGAGAGAATCTGCTTTTGTGATTTTCAATAATCATGATACAGTTGATAAAACTGTTGTTCAGAAATA
TTACAGTATTAATGGGCTTAATTGTGAAGTGAAAAAGGCCCTTTCTAAACAAGAGATGGCAGTCTGCTGGACCACAGAGA
TCGTGGAGGTGGATCTGACAACTCTATGGGCCCTGGAGGGATGTCTGGAGGGGGTGGAGGGAACTTTGGCCATGGTGGAA
ACTTTGGTGGAAGAGGAGGCTATGGTGGGGAAGGTCGTGGCAGCAGAAGCAGTCATGGAAGAGGTGATGGTGGATATAAT
GGAATTAGAGGTGATAGTGGCAGCTATGGCAGTGGTCCTGGTTAGAGCAGAGGGGGCTATGGTGGTGGTAGACCAGGATA
TGGA

Alignment

ORF - retro_chof_2574 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 54.01 %
• Parental protein coverage: 77.51 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  REKEQFRKLFIGGLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRG-GFVTFSSMAEVDAAMAARPH
          .E.EQ.RKLF.GGLS.ET...SL....E....LTDC.VMRDP..K.SR..GFVT.S...EV.AAM.A..H
Retrocopy KESEQLRKLFTGGLSSETMDDSLEEHCEK*STLTDCMVMRDPQTKCSRSFGFVTYSCVEEVGAAMCA*LH

Parental  SIDGRVVEPKRAV-AREESGKPGAHVTV-KKL-FVGGIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGK
          ..DG.V.EPKR....RE.S.KPGA..TV.KKL.FVGGIK.DTEE..LR.YFE...K....E...DRQSGK
Retrocopy KVDGCVEEPKRVA<SREDSVKPGAPLTVKKKL<FVGGIKGDTEEYNLRHYFEKSSKTEAKEVTEDRQSGK

Parental  KRGFGFVTFDDHDPVDKIVLQKYHTINGHNAEVRKALSRQEM-QEVQSSRS-GRGGNFGFG-DSRGGGGN
          KR...FV.F..HD.VDK.V.QKY..ING.N.EV.KALS.QEM.Q.....RS.G.G.....G.....GGG.
Retrocopy KRESAFVIFNNHDTVDKTVVQKYYSINGLNCEVKKALSKQEM>QSAGPQRS>GGGSDNSMGPGGMSGGGG

Parental  FGPGPGSNFRG----GSDGYGSGRGFGDGYNGYGGGPG-GGNFGGSPGYGGGRGGYGGGGPGYG
          ...G.G.NF.G....G..G.GS....G.G..GY.G..G..G..G..P..G..RGGYGGG.PGYG
Retrocopy GNFGHGGNFGGRGGYGGEGRGSRSSHGRGDGGYNGIRGDSGSYGSGP--G*SRGGYGGGRPGYG

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2574 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 58 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000005726	4 retrocopies	retro_btau_1330, retro_btau_1535, retro_btau_193, retro_btau_228,
Choloepus hoffmanni	ENSCHOG00000000160	8 retrocopies	retro_chof_115, retro_chof_1470, retro_chof_2108, retro_chof_2370, retro_chof_533, retro_chof_59, retro_chof_741, retro_chof_890,
Choloepus hoffmanni	ENSCHOG00000003275	2 retrocopies	retro_chof_1578, retro_chof_18,
Choloepus hoffmanni	ENSCHOG00000013832	15 retrocopies	retro_chof_1060, retro_chof_1191, retro_chof_1413, retro_chof_1460, retro_chof_1507, retro_chof_2062, retro_chof_2135, retro_chof_2235, retro_chof_2263, retro_chof_2404, retro_chof_2425, retro_chof_2473, retro_chof_2574 , retro_chof_499, retro_chof_853,
Ciona intestinalis	ENSCING00000004062	1 retrocopy	retro_cint_7,
Callithrix jacchus	ENSCJAG00000007908	2 retrocopies	retro_cjac_2285, retro_cjac_3041,
Ciona savignyi	ENSCSAVG00000000472	1 retrocopy	retro_csav_26,
Dasypus novemcinctus	ENSDNOG00000012928	1 retrocopy	retro_dnov_1978,
Dipodomys ordii	ENSDORG00000005482	1 retrocopy	retro_dord_489,
Echinops telfairi	ENSETEG00000018577	1 retrocopy	retro_etel_1368,
Felis catus	ENSFCAG00000027765	1 retrocopy	retro_fcat_692,
Macropus eugenii	ENSMEUG00000001084	2 retrocopies	retro_meug_1897, retro_meug_214,
Myotis lucifugus	ENSMLUG00000007578	1 retrocopy	retro_mluc_34,
Mus musculus	ENSMUSG00000004980	1 retrocopy	retro_mmus_573,
Oryctolagus cuniculus	ENSOCUG00000026859	2 retrocopies	retro_ocun_1205, retro_ocun_642,
Otolemur garnettii	ENSOGAG00000015353	3 retrocopies	retro_ogar_1384, retro_ogar_3077, retro_ogar_3189,
Ochotona princeps	ENSOPRG00000011698	2 retrocopies	retro_opri_165, retro_opri_893,
Rattus norvegicus	ENSRNOG00000011175	3 retrocopies	retro_rnor_1824, retro_rnor_2043, retro_rnor_2339,
Ictidomys tridecemlineatus	ENSSTOG00000006202	3 retrocopies	retro_itri_1723, retro_itri_448, retro_itri_717,
Tursiops truncatus	ENSTTRG00000000709	3 retrocopies	retro_ttru_1066, retro_ttru_1204, retro_ttru_1788,
Vicugna pacos	ENSVPAG00000010417	1 retrocopy	retro_vpac_616,