RetrogeneDB ID: retro_cfam_1225

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 27:26048077..26049131(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCAFG00000012292
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000012160
• Aliases: None
• Description: None

Sequence

>retro_cfam_1225
CCCACTAGTTATCCCCCCCAAACTGGATCCTATAGCCAGGCTCCAAGTCAATATAGCCAACAGAGCAGCAGCTATGGGCA
GCAGAGTTCATTCCGACAGTACCACCCCAGTAGCATGGGTGTTTATGGGCAGGAGTCTGGAGGATTTTCCGGACCAGGAG
AGAACCAGAGCATGAGTGGCCTTGAAAACCGGGGCAGGGGAAGAGGGGGATTTGATTGTGGAGGCATAAGCGGAGGTGGG
TGGGGAGGAGGACTCGGTGGAATGGGCGCTGGAGAGCGAGGTGGCTTCAATAAGCCTGGTGGATCCATGGATGAAGGACC
AGCTCTTAATCTAGGCCCACCTGTAGATCCAGATGAAGACTCTGACAACCGTGCAATTTATGTGCAAGGCTTGAATGACA
ATGTGACTCTAGATGATCTGGCTGACTTCTTTAAGCAGTGTGGAGTTAATAAGATGAACAAGAGAACCGGACAACCCATG
ATCCATATCTACTTGGACAAGGAAAGAGGAAAGCCCAAAGGTGATGCTACAGTATCCTATGAAGACCCACCAACTGCCAA
GGCTGCTGTGGAGTGGTTTGATGGGAGAGATTTTCAAGGAAGCAAACTTAAGGTTTCTCTTGCTCGGAAGAAACCTCCGA
TGAACAGCATGCGGGGTCGTATGCCTTCCAGTGAGGGCAAAGGTGTGCCACCGCCACTCCGTGGAGGTCCAGGGGGCCCA
GGAGGTCCTGGGGGCCCCATGGGTCGCATGGGAGGCCGTGGTGGAGACAGAGGTGGCTTTCCCCCAAGAGGACCCCGGGT
TCCCGGGGAGGAAACGTCCATCCGGAGGAGGAAACTTCCAGCACCGGACTGGGGACTGGCAGTGCCCCATTCCGGGCTGT
GGAAACCAGAACTTCGCCTGGAGAACAGAATGCAACCAGTGTAAGGCCTCGAAGCCTGAAGGCTTCCTTCCACCACCCTT
CCCGCCCCCGGGCAGTGACCGTGGCAGAGGTGGCCCTGGTGGCATGCGGGGAGGAAGAGGTGGCCTCATGGACCGCGGTG
CTCTCGGTGCGGTG

Alignment

ORF - retro_cfam_1225 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.1 %
• Parental protein coverage: 52.31 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQDHPSSMGVYGQESGGFSGPGENRSMSGPDNRGRGRGG
          PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQ.HPSSMGVYGQESGGFSGPGEN.SMSG..NRGRGRGG
Retrocopy PTSYPPQTGSYSQAPSQYSQQSSSYGQQSSFRQYHPSSMGVYGQESGGFSGPGENQSMSGLENRGRGRGG

Parental  FDRGGMSRGGRGGGRGGMGSAGERGGFNKPGGPMDEGPDLDKGPPVDPDEDSDNSAIYVQGLNDNVTLDD
          FD.GG.S.GG.GGG.GGMG.AGERGGFNKPGG.MDEGP.L..GPPVDPDEDSDN.AIYVQGLNDNVTLDD
Retrocopy FDCGGISGGGWGGGLGGMG-AGERGGFNKPGGSMDEGPALNLGPPVDPDEDSDNRAIYVQGLNDNVTLDD

Parental  LADFFKQCGVVKMNKRTGQPMIHIYLDKETGKPKGDATVSYEDPPTAKAAVEWFDGKDFQGSKLKVSLAR
          LADFFKQCGV.KMNKRTGQPMIHIYLDKE.GKPKGDATVSYEDPPTAKAAVEWFDG.DFQGSKLKVSLAR
Retrocopy LADFFKQCGVNKMNKRTGQPMIHIYLDKERGKPKGDATVSYEDPPTAKAAVEWFDGRDFQGSKLKVSLAR

Parental  KKPPMNSMRGGMPPREGRGMPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGF-PPRGPR-GSRGNPSGGGN
          KKPPMNSMRG.MP..EG.G.PPPLRGGPGGPGGPGGPMGRMGGRGGDRGGF.P...P....R..PSGGGN
Retrocopy KKPPMNSMRGRMPSSEGKGVPPPLRGGPGGPGGPGGPMGRMGGRGGDRGGF>PQEDPGFPGRKRPSGGGN

Parental  VQHRAGDWQCPNPGCGNQNFAWRTECNQCKAPKPEGFLPPPFPPPGGDRGRGGPGGMRGGRGGLMDRGGP
          .QHR.GDWQCP.PGCGNQNFAWRTECNQCKA.KPEGFLPPPFPPPG.DRGRGGPGGMRGGRGGLMDRG..
Retrocopy FQHRTGDWQCPIPGCGNQNFAWRTECNQCKASKPEGFLPPPFPPPGSDRGRGGPGGMRGGRGGLMDRGAL

Parental  GGM
          G..
Retrocopy GAV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	77.74 RPM
SRP017611_brain	0.00 RPM	36.04 RPM
SRP017611_kidney	0.00 RPM	45.24 RPM
SRP017611_liver	0.00 RPM	33.94 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1225 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1225 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1225 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000008298	2 retrocopies	retro_amel_191, retro_amel_959,
Canis familiaris	ENSCAFG00000012160	8 retrocopies	retro_cfam_1142, retro_cfam_1183, retro_cfam_1225 , retro_cfam_133, retro_cfam_1397, retro_cfam_1736, retro_cfam_1889, retro_cfam_560,
Callithrix jacchus	ENSCJAG00000019987	4 retrocopies	retro_cjac_1716, retro_cjac_2022, retro_cjac_2813, retro_cjac_2911,
Cavia porcellus	ENSCPOG00000009502	1 retrocopy	retro_cpor_1353,
Felis catus	ENSFCAG00000004243	1 retrocopy	retro_fcat_519,
Homo sapiens	ENSG00000182944	1 retrocopy	retro_hsap_463,
Gorilla gorilla	ENSGGOG00000012212	1 retrocopy	retro_ggor_444,
Macropus eugenii	ENSMEUG00000008703	1 retrocopy	retro_meug_1424,
Myotis lucifugus	ENSMLUG00000012058	1 retrocopy	retro_mluc_328,
Monodelphis domestica	ENSMODG00000008679	1 retrocopy	retro_mdom_279,
Mustela putorius furo	ENSMPUG00000013432	2 retrocopies	retro_mputfur_56, retro_mputfur_572,
Mus musculus	ENSMUSG00000009079	1 retrocopy	retro_mmus_1379,
Oryctolagus cuniculus	ENSOCUG00000004432	2 retrocopies	retro_ocun_1346, retro_ocun_242,
Pongo abelii	ENSPPYG00000011684	1 retrocopy	retro_pabe_1769,
Pan troglodytes	ENSPTRG00000014218	1 retrocopy	retro_ptro_350,
Ictidomys tridecemlineatus	ENSSTOG00000023177	1 retrocopy	retro_itri_1892,
Tursiops truncatus	ENSTTRG00000011881	1 retrocopy	retro_ttru_1366,