RetrogeneDB ID: retro_acar_187

Retrocopy location

• Organism: Anole lizard (Anolis carolinensis)
• Coordinates: GL343406.1:701111..701633(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TMED10
• Ensembl ID: ENSACAG00000016899
• Aliases: None
• Description: None

Sequence

>retro_acar_187
ATCCACCGGGACACGCTGGTCACCGGCGAGTACAAGGTCGCCTCGCTGCCAGGCTCATCCAGTGGGCCCTCCGTCAACCT
CAAGATTACTGACTCATTTGGGCACATTCTCTATTCCAAGGAGGATGCTATTAAAGACAAATTTGCTTTCACCACAGAAG
ACTATGATATGTTTGAGGCCTGCTTTGAGAGCAAACTCCCTGTAGGAACAGGGCAGATGCCAGACCAGCCTGTGACCTTG
ACTATGAAGCATGGAGTAGAAGCAAAGAACCACAAGGAGATTAATAAAGTTGAGAAGTTGAAGCCATTGGAGCTGGAGCT
GCAAAGACTAGAAGATATTTCAGAATCTATTGTCAATGACTTTTCCTATATGAAGAAGCAAGAGGAAGAGATGTGAGATA
CAGAGTCTACCAACATTCGAGTATTATACTTCCGCATTTTCTCCATGTTCTGCCTCATTGGACGGGCTACCTGGCAGGTC
TTCTATCTGCGCCATTTCTTCAAAGCCAAAAAGCTTATTGAA

Alignment

ORF - retro_acar_187 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 89.14 %
• Parental protein coverage: 81.78 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  IHRDTLVTGEYEVASPPGSPSGPSANLKITDSSGHILYSKEDAIKGKFAFTTEDYDMFEACFESKLPVGT
          IHRDTLVTGEY.VAS.PGS.SGPS.NLKITDS.GHILYSKEDAIK.KFAFTTEDYDMFEACFESKLPVGT
Retrocopy IHRDTLVTGEYKVASLPGSSSGPSVNLKITDSFGHILYSKEDAIKDKFAFTTEDYDMFEACFESKLPVGT

Parental  GRMPDQLVTLTMKHGVEAKNYEEIAKVEKLKPLELELRRLEDLSESIVNDFAYMKKREEEMRDTNESTNI
          G.MPDQ.VTLTMKHGVEAKN..EI.KVEKLKPLELEL.RLED.SESIVNDF.YMKK.EEEM.DT.ESTNI
Retrocopy GQMPDQPVTLTMKHGVEAKNHKEINKVEKLKPLELELQRLEDISESIVNDFSYMKKQEEEM*DT-ESTNI

Parental  RVLYFSIFSMFCLIGLATWQVFYLRHFFKAKKLIE
          RVLYF.IFSMFCLIG.ATWQVFYLRHFFKAKKLIE
Retrocopy RVLYFRIFSMFCLIGRATWQVFYLRHFFKAKKLIE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP009831_adrenal	1.61 RPM	237.93 RPM
SRP009831_brain	0.00 RPM	51.08 RPM
SRP009831_dewlap	0.00 RPM	83.87 RPM
SRP009831_embryo	0.30 RPM	130.85 RPM
SRP009831_heart	0.00 RPM	96.24 RPM
SRP009831_liver	0.04 RPM	107.57 RPM
SRP009831_lung	0.00 RPM	100.59 RPM
SRP009831_ovary	0.04 RPM	96.56 RPM
SRP009831_skeletal_muscle	0.00 RPM	129.41 RPM

ChIP-Seq

Anolis carolinensis was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_acar_187 retrocopy.

TSS

Anolis carolinensis was not studied using FANTOM5 data.

Lab

retro_acar_187 was not experimentally validated.

Homology

Retrocopy orthology:

Anolis carolinensis does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000016899	1 retrocopy	retro_acar_187 ,
Callithrix jacchus	ENSCJAG00000020627	2 retrocopies	retro_cjac_1409, retro_cjac_4223,
Dasypus novemcinctus	ENSDNOG00000019851	1 retrocopy	retro_dnov_1225,
Echinops telfairi	ENSETEG00000010607	1 retrocopy	retro_etel_1798,
Homo sapiens	ENSG00000170348	2 retrocopies	retro_hsap_2701, retro_hsap_4014,
Gorilla gorilla	ENSGGOG00000007453	1 retrocopy	retro_ggor_2696,
Myotis lucifugus	ENSMLUG00000017125	2 retrocopies	retro_mluc_2079, retro_mluc_2093,
Macaca mulatta	ENSMMUG00000015168	2 retrocopies	retro_mmul_2316, retro_mmul_885,
Mus musculus	ENSMUSG00000021248	2 retrocopies	retro_mmus_1093, retro_mmus_649,
Nomascus leucogenys	ENSNLEG00000016453	2 retrocopies	retro_nleu_2897, retro_nleu_2963,
Oryctolagus cuniculus	ENSOCUG00000004669	1 retrocopy	retro_ocun_875,
Pongo abelii	ENSPPYG00000029389	1 retrocopy	retro_pabe_3296,
Pan troglodytes	ENSPTRG00000006552	2 retrocopies	retro_ptro_1823, retro_ptro_2724,
Rattus norvegicus	ENSRNOG00000007901	2 retrocopies	retro_rnor_1729, retro_rnor_2031,
Ictidomys tridecemlineatus	ENSSTOG00000007392	1 retrocopy	retro_itri_362,
Vicugna pacos	ENSVPAG00000003089	1 retrocopy	retro_vpac_573,