RetrogeneDB ID: retro_rnor_2922

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: X:58502236..58503019(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Rpl5
• Ensembl ID: ENSRNOG00000023529
• Aliases: None
• Description: 60S ribosomal protein L5 [Source:UniProtKB/Swiss-Prot;Acc:P09895]

Sequence

>retro_rnor_2922
ATGAGGTTCAGGAAAGTTGTCAAGTATAAGGCCTACTTTAAAAAATATCAAGGGAGATTTAGATGGCAATAAGAGGGTAA
AACTGACTACTATGCACAGAAATGATTGGTGATCCATGACAAAAATAAGAACAACACACCCAAATATAGGATGATAGTTC
ATGTAACTAACGGAGATATCACCTTCTGGACAGCATATGCTCCTATAGAAGGGAATATGATGATCTGTGTAGCACATGCA
TATGAATTTCCAAAATATGATGTGAAATTTAGTCTTACAAATTATGCTTCAGCCTATTGCACTGGCCTGCTGCTGGTCTG
CAAACTTAGATTTGGCATAGACAAGATCTATGAAGTCCAAGTGGATGTGAAGGAAGATAAATACAATGTGGAAAACATTG
ACATTCAGCCTTATACCTTCACTTGCTATTTGGATGCAGGTCTTGCCCAAATTAAAACTGGCAATAAAATTTTTGTGGTC
CTCAAGGGAGCTGTGGATGGAGGCTTATCTATCCCTCATAGTACCAATTGATTTCCTGGTTATGTCTCTGAAAGCAAGTA
GTTCAATGCAGAGGTACATCGGAAACACATCATGGGTCAGAATGTGGCAGACTATATGTGCTACTAGTGGAGGAATATGA
AGATGTGTATAAGAAATAATTTTCTCAGTGCATCAAGAACAGTGTAATTCCAGACATGATGGAAGAGATTTATAAGAAAA
CTCATTCTGCTATCTGAGAGAATCCAGTCTGAGAAGAAGCCCAAGAGAGAAGTGAAGAAGGAG

Alignment

ORF - retro_rnor_2922 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 71.91 %
• Parental protein coverage: 88.89 %
• Number of stop codons detected: 7
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MGFVKVVKNKAYFKRYQVRFRRRREGKTDYYARKRLVIQDKNKYNTPKYRMIVRVTNRDIICQIAYARIE
          M.F.KVVK.KAYFK.YQ.RFR...EGKTDYYA.K.LVI.DKNK.NTPKYRMIV.VTN.DI....AYA.IE
Retrocopy MRFRKVVKYKAYFKKYQGRFRWQ*EGKTDYYAQK*LVIHDKNKNNTPKYRMIVHVTNGDITFWTAYAPIE

Parental  GDMIVCAAYAHELPKYGVKVGLTNYAAAYCTGLLLARRLLNRFGMDKIYEGQVEVNGDEYNVESIDGQPG
          G.M..C.A.A.E.PKY.VK..LTNYA.AYCTGLLL...L..RFG.DKIYE.QV.V..D.YNVE.ID.QP.
Retrocopy GNMMICVAHAYEFPKYDVKFSLTNYASAYCTGLLLVCKL--RFGIDKIYEVQVDVKEDKYNVENIDIQPY

Parental  AFTCYLDAGLARTTTGNKVFGALKGAVDGGLSIPHSTKRFPGYDSESKEFNAEVHRKHIMGQNVADYMRY
          .FTCYLDAGLA...TGNK.F..LKGAVDGGLSIPHST..FPGY.SESK.FNAEVHRKHIMGQNVADYM.Y
Retrocopy TFTCYLDAGLAQIKTGNKIFVVLKGAVDGGLSIPHSTN*FPGYVSESK*FNAEVHRKHIMGQNVADYMCY

Parental  -LMEEDEDAYKKQFSQYIKNNVTPDMMEEMYKKAHAAIRENPVYE-KKPK-REVKKK
          .L.EE.ED.YKK.FSQ.IKN.V.PDMMEE.YKK.H.AI.ENPV.E...P..REVKK.
Retrocopy <LVEEYEDVYKK*FSQCIKNSVIPDMMEEIYKKTHSAI*ENPV*E<RSPR<REVKKE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	103.75 RPM
SRP017611_kidney	0.00 RPM	183.25 RPM
SRP017611_liver	0.00 RPM	112.29 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_2922 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_2922 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_2922 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 66 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000009878	5 retrocopies	retro_amel_1200, retro_amel_137, retro_amel_139, retro_amel_1439, retro_amel_1669,
Bos taurus	ENSBTAG00000002026	2 retrocopies	retro_btau_120, retro_btau_67,
Cavia porcellus	ENSCPOG00000000698	8 retrocopies	retro_cpor_1047, retro_cpor_1097, retro_cpor_1141, retro_cpor_1259, retro_cpor_1354, retro_cpor_1387, retro_cpor_428, retro_cpor_737,
Dipodomys ordii	ENSDORG00000005674	2 retrocopies	retro_dord_226, retro_dord_670,
Equus caballus	ENSECAG00000021065	1 retrocopy	retro_ecab_654,
Macropus eugenii	ENSMEUG00000006361	3 retrocopies	retro_meug_1168, retro_meug_1537, retro_meug_2146,
Monodelphis domestica	ENSMODG00000011635	1 retrocopy	retro_mdom_748,
Mustela putorius furo	ENSMPUG00000004150	6 retrocopies	retro_mputfur_213, retro_mputfur_449, retro_mputfur_451, retro_mputfur_597, retro_mputfur_721, retro_mputfur_833,
Mus musculus	ENSMUSG00000058558	11 retrocopies	retro_mmus_1000, retro_mmus_1185, retro_mmus_1338, retro_mmus_1789, retro_mmus_1991, retro_mmus_2577, retro_mmus_2846, retro_mmus_297, retro_mmus_3076, retro_mmus_504, retro_mmus_911,
Ornithorhynchus anatinus	ENSOANG00000004669	1 retrocopy	retro_oana_97,
Oryctolagus cuniculus	ENSOCUG00000010089	2 retrocopies	retro_ocun_265, retro_ocun_54,
Petromyzon marinus	ENSPMAG00000002040	1 retrocopy	retro_pmar_23,
Pteropus vampyrus	ENSPVAG00000015117	4 retrocopies	retro_pvam_1427, retro_pvam_355, retro_pvam_505, retro_pvam_527,
Rattus norvegicus	ENSRNOG00000023529	6 retrocopies	retro_rnor_113, retro_rnor_2246, retro_rnor_2418, retro_rnor_2498, retro_rnor_2802, retro_rnor_2922 ,
Sarcophilus harrisii	ENSSHAG00000006417	1 retrocopy	retro_shar_202,
Sus scrofa	ENSSSCG00000006899	2 retrocopies	retro_sscr_149, retro_sscr_219,
Tupaia belangeri	ENSTBEG00000010560	5 retrocopies	retro_tbel_101, retro_tbel_1054, retro_tbel_1518, retro_tbel_3006, retro_tbel_3530,
Tursiops truncatus	ENSTTRG00000013097	5 retrocopies	retro_ttru_1446, retro_ttru_1548, retro_ttru_1796, retro_ttru_645, retro_ttru_979,