RetrogeneDB ID: retro_rnor_2375

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 6:81854031..81854567(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Arl1
• Ensembl ID: ENSRNOG00000005763
• Aliases: None
• Description: ADP-ribosylation factor-like protein 1 [Source:UniProtKB/Swiss-Prot;Acc:P61212]

Sequence

>retro_rnor_2375
GGCTTTTTCTCAAGTACTTTTTCTAGTCTCTTTGGAACCACGGAAATGAGGATTTTAATTTTGGGATTAGATGGTGCTGG
AAAAATGACAATTTTGTACAGATTACAGGTTAGAGAAGTTGTTATTACTATTCCCACTATTGGATTTAAAGTAGAGATGG
TGACATACAAAAATCTCAAATTCCAAGTTTGGGACTTAGGAGAACAGATAAGTATCAGGCCATACTGGAGATGTTATTAT
TCAAACACAGATGCAGTCATCTAAGTCGTTGACAGTTGTGACTGAGACCGAATTGGCATTTCCTGGTCAGAGTTAGTTGC
CACATTAGAGGAAGAAGAGCTGAGAAAAGCCATTTTAGTGGTGTTTGCAAACAAGCAGGCCATGGAACAGGCCGTGACGC
CCTCGGAAATGGCAAATGCTCTTGGGTTACCGCCCTGAAGGACCGGAAGTGACAGATCTTTAAAACGTCGGCAACCAAAG
TCATTGGCCTGGACAAGGCAATAGAATGGTTAGTTGAAACACTGAAAAGCAGACAG

Alignment

ORF - retro_rnor_2375 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.33 %
• Parental protein coverage: 98.9 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GFFSSIFSSLFGTREMRILILGLDGAGKTTILYRLQVGEVVTTIPTIGFNVETVTYKNLKFQVWDLGGQT
          GFFSS.FSSLFGT.EMRILILGLDGAGK.TILYRLQV.EVV.TIPTIGF.VE.VTYKNLKFQVWDLG.Q.
Retrocopy GFFSSTFSSLFGTTEMRILILGLDGAGKMTILYRLQVREVVITIPTIGFKVEMVTYKNLKFQVWDLGEQI

Parental  SIRPYWRCYYSNTDAVIYVVDSCDRDRIGISKSELVAMLEEEELRKAILVVFANKQDMEQAMTPSEMANA
          SIRPYWRCYYSNTDAVI.VVDSCD.DRIGIS.SELVA.LEEEELRKAILVVFANKQ.MEQA.TPSEMANA
Retrocopy SIRPYWRCYYSNTDAVI*VVDSCD*DRIGISWSELVATLEEEELRKAILVVFANKQAMEQAVTPSEMANA

Parental  LGLP-ALKDRKWQIFKTSATKGTGLDEAMEWLVETLKSRQ
          LGLP.ALKDRK.QIFKTSATK..GLD.A.EWLVETLKSRQ
Retrocopy LGLP<ALKDRK*QIFKTSATKVIGLDKAIEWLVETLKSRQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.00 RPM	57.23 RPM
SRP017611_kidney	0.00 RPM	69.57 RPM
SRP017611_liver	0.00 RPM	41.62 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_2375 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_2375 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_2375 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 35 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000016452	2 retrocopies	retro_amel_1138, retro_amel_713,
Canis familiaris	ENSCAFG00000006992	2 retrocopies	retro_cfam_1176, retro_cfam_709,
Callithrix jacchus	ENSCJAG00000001966	1 retrocopy	retro_cjac_2938,
Echinops telfairi	ENSETEG00000020310	1 retrocopy	retro_etel_1850,
Macropus eugenii	ENSMEUG00000015525	1 retrocopy	retro_meug_518,
Myotis lucifugus	ENSMLUG00000002351	1 retrocopy	retro_mluc_255,
Monodelphis domestica	ENSMODG00000003056	1 retrocopy	retro_mdom_677,
Mustela putorius furo	ENSMPUG00000011822	1 retrocopy	retro_mputfur_1458,
Mus musculus	ENSMUSG00000060904	1 retrocopy	retro_mmus_3285,
Oryctolagus cuniculus	ENSOCUG00000002217	5 retrocopies	retro_ocun_1608, retro_ocun_399, retro_ocun_400, retro_ocun_465, retro_ocun_847,
Otolemur garnettii	ENSOGAG00000015144	1 retrocopy	retro_ogar_1239,
Pteropus vampyrus	ENSPVAG00000008119	2 retrocopies	retro_pvam_1072, retro_pvam_715,
Rattus norvegicus	ENSRNOG00000001689	1 retrocopy	retro_rnor_2142,
Rattus norvegicus	ENSRNOG00000005763	1 retrocopy	retro_rnor_2375 ,
Sorex araneus	ENSSARG00000013944	4 retrocopies	retro_sara_237, retro_sara_304, retro_sara_479, retro_sara_71,
Sarcophilus harrisii	ENSSHAG00000004634	2 retrocopies	retro_shar_204, retro_shar_275,
Ictidomys tridecemlineatus	ENSSTOG00000016022	2 retrocopies	retro_itri_1000, retro_itri_348,
Tarsius syrichta	ENSTSYG00000013257	5 retrocopies	retro_tsyr_1803, retro_tsyr_188, retro_tsyr_350, retro_tsyr_369, retro_tsyr_809,
Tursiops truncatus	ENSTTRG00000017202	1 retrocopy	retro_ttru_701,