RetrogeneDB ID: retro_rnor_1283

Retrocopy location

• Organism: Rat (Rattus norvegicus)
• Coordinates: 17:1897691..1898180(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSRNOG00000018554
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Srsf3
• Ensembl ID: ENSRNOG00000000520
• Aliases: Srsf3, Sfrs3
• Description: splicing factor, arginine/serine-rich 3 [Source:RefSeq peptide;Acc:NP_001041372]

Sequence

>retro_rnor_1283
ATGCATCGTGATTCCTGTCCCTTGGACTGTAAGGTTTATGTAGGTAATCTTGGAAACAATGGGAACAAGACTGAATTAGA
ACGGGCTTTTGGCTATTATGGACCACTCCGAAGTGTGTGGGTTGCTCGAAACCCTCCTGGCTTTGCTTTCGTCGAATTTG
AGGATCCCCGAGATGCTGCTGATGCTGTCCGAGAGCTAGATGGAAGAACACTATGTGGCTGCCGTGTAAGAGTGGAACTG
TCGAATGGTGAAAAGAGAAGTCGGAATCGTGGCCCGCCTCCCTCTTGGGGTCGTCGTCCTCGAGATGATTACCGCAGGAG
GAGTCCTCCACCTCGGCGCAGATCCCCAAGGAGAAGCTTTTCGCGAAGCCGGAGCAGGTCTCTTTCTAGAGATAGGAGAA
GAGAAAGGTCTCTGTCTCGTGAGAGAAATCACAAGCCGTCTTGATCCTTCTCTAGGTCTCGTAGCTGATCTAGGTCAAAT
GAAAGGAAA

Alignment

ORF - retro_rnor_1283 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.17 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT
          MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT
Retrocopy MHRDSCPLDCKVYVGNLGNNGNKTELERAFGYYGPLRSVWVARNPPGFAFVEFEDPRDAADAVRELDGRT

Parental  LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRRRSFSRSRSRSLSRDRRRERSLS
          LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRR.SFSRSRSRSLSRDRRRERSLS
Retrocopy LCGCRVRVELSNGEKRSRNRGPPPSWGRRPRDDYRRRSPPPRRRSPRR-SFSRSRSRSLSRDRRRERSLS

Parental  RERNHKPSRSFSRSRSRSRSNERK
          RERNHKPS.SFSRSRS.SRSNERK
Retrocopy RERNHKPS*SFSRSRS*SRSNERK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.07 RPM	65.21 RPM
SRP017611_kidney	0.28 RPM	69.92 RPM
SRP017611_liver	0.00 RPM	38.86 RPM

ChIP-Seq

Rattus norvegicus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_rnor_1283 retrocopy.

TSS

Rattus norvegicus was not studied using FANTOM5 data.

Lab

retro_rnor_1283 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_rnor_1283 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 91 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000040006	5 retrocopies	retro_btau_1176, retro_btau_1442, retro_btau_1445, retro_btau_1665, retro_btau_1813,
Callithrix jacchus	ENSCJAG00000016062	5 retrocopies	retro_cjac_1035, retro_cjac_1969, retro_cjac_2006, retro_cjac_620, retro_cjac_746,
Homo sapiens	ENSG00000112081	4 retrocopies	retro_hsap_2140, retro_hsap_2299, retro_hsap_2304, retro_hsap_757,
Loxodonta africana	ENSLAFG00000018193	2 retrocopies	retro_lafr_1219, retro_lafr_80,
Microcebus murinus	ENSMICG00000004674	5 retrocopies	retro_mmur_1090, retro_mmur_160, retro_mmur_287, retro_mmur_710, retro_mmur_916,
Myotis lucifugus	ENSMLUG00000010671	6 retrocopies	retro_mluc_1205, retro_mluc_1312, retro_mluc_1554, retro_mluc_2283, retro_mluc_278, retro_mluc_51,
Mustela putorius furo	ENSMPUG00000014215	1 retrocopy	retro_mputfur_613,
Mus musculus	ENSMUSG00000071172	9 retrocopies	retro_mmus_100, retro_mmus_1347, retro_mmus_1749, retro_mmus_2294, retro_mmus_2337, retro_mmus_2433, retro_mmus_2654, retro_mmus_2933, retro_mmus_3629,
Otolemur garnettii	ENSOGAG00000000502	6 retrocopies	retro_ogar_1850, retro_ogar_1959, retro_ogar_2131, retro_ogar_2783, retro_ogar_597, retro_ogar_803,
Ochotona princeps	ENSOPRG00000006006	3 retrocopies	retro_opri_1037, retro_opri_158, retro_opri_545,
Rattus norvegicus	ENSRNOG00000000520	11 retrocopies	retro_rnor_1010, retro_rnor_1283 , retro_rnor_1321, retro_rnor_1339, retro_rnor_1647, retro_rnor_1697, retro_rnor_1889, retro_rnor_2424, retro_rnor_634, retro_rnor_728, retro_rnor_790,
Rattus norvegicus	ENSRNOG00000005513	1 retrocopy	retro_rnor_2900,
Rattus norvegicus	ENSRNOG00000006380	1 retrocopy	retro_rnor_1752,
Rattus norvegicus	ENSRNOG00000027360	11 retrocopies	retro_rnor_1535, retro_rnor_1977, retro_rnor_1984, retro_rnor_2419, retro_rnor_2420, retro_rnor_2421, retro_rnor_2495, retro_rnor_2501, retro_rnor_2502, retro_rnor_2503, retro_rnor_478,
Sus scrofa	ENSSSCG00000001564	1 retrocopy	retro_sscr_1038,
Ictidomys tridecemlineatus	ENSSTOG00000014280	5 retrocopies	retro_itri_123, retro_itri_502, retro_itri_664, retro_itri_857, retro_itri_901,
Tarsius syrichta	ENSTSYG00000013498	3 retrocopies	retro_tsyr_1867, retro_tsyr_2163, retro_tsyr_848,
Tursiops truncatus	ENSTTRG00000013447	11 retrocopies	retro_ttru_105, retro_ttru_1195, retro_ttru_1577, retro_ttru_1628, retro_ttru_1639, retro_ttru_1653, retro_ttru_1677, retro_ttru_1731, retro_ttru_1892, retro_ttru_610, retro_ttru_916,
Vicugna pacos	ENSVPAG00000005481	1 retrocopy	retro_vpac_541,