RetrogeneDB ID: retro_pabe_855

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 12:64429152..64429507(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS11
• Ensembl ID: ENSPPYG00000025860
• Aliases: None
• Description: ribosomal protein S11 [Source:HGNC Symbol;Acc:10384]

Sequence

>retro_pabe_855
ATGGTGGACATTGAGACTGAGCATGCCTACCACAAGCAGCTGACCATCATTCAAAGCAAGAAGAGGGTCCTGCTAAAGGA
AACTGACAAGGAGCAGCTCCTATGGTACTTACAAGAACATCAGTCTAGGCTTCAAGAGGTCCAAAGAGACGATTGAGGGC
ACCTACATTGACAGGGAATGCCTGTTCACTGGTAACATCTCCATCTGAGGGCAGATTCTGTATGGCATGGTGACCAAGAT
GGAGATGCAGAGGGCCACTGTCATCCACAGAAACTATCTCCACTACATCCACAAGTACAATTGCTTCGAGAAGTACCACA
AGAACATGTCCATGCACCTGTTCCCCTGCTTCAGG

Alignment

ORF - retro_pabe_855 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.59 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MADIQTERAYQKQPTIFQNKKRVLLGETGKEKLPRY-YKNIGLGFKTPKEAIEGTYIDKKCPFTGNVSIR
          M.DI.TE.AY.KQ.TI.Q.KKRVLL.ET.KE.L..Y.YKNI.LGFK..KE.IEGTYID..C.FTGN.SI.
Retrocopy MVDIETEHAYHKQLTIIQSKKRVLLKETDKEQLLWY>YKNISLGFKRSKETIEGTYIDRECLFTGNISI*

Parental  GRILSGVVTKMKMQRTIVIRRDYLHYIRKYNRFEKRHKNMSVHLSPCFR
          G.IL.G.VTKM.MQR..VI.R.YLHYI.KYN.FEK.HKNMS.HL.PCFR
Retrocopy GQILYGMVTKMEMQRATVIHRNYLHYIHKYNCFEKYHKNMSMHLFPCFR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.06 RPM	195.29 RPM
SRP007412_cerebellum	0.24 RPM	131.21 RPM
SRP007412_heart	0.03 RPM	163.28 RPM
SRP007412_kidney	0.10 RPM	398.29 RPM
SRP007412_liver	0.00 RPM	259.81 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_855 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_855 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_855 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1017
Gorilla gorilla	retro_ggor_805
Macaca mulatta	retro_mmul_813

---

Parental genes homology:

Parental genes homology involve 20 parental genes, and 110 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000014020	13 retrocopies	retro_amel_1038, retro_amel_1071, retro_amel_1398, retro_amel_1406, retro_amel_1475, retro_amel_246, retro_amel_262, retro_amel_317, retro_amel_64, retro_amel_757, retro_amel_759, retro_amel_764, retro_amel_859,
Bos taurus	ENSBTAG00000013924	5 retrocopies	retro_btau_1282, retro_btau_1369, retro_btau_1499, retro_btau_1529, retro_btau_888,
Canis familiaris	ENSCAFG00000003631	9 retrocopies	retro_cfam_126, retro_cfam_1333, retro_cfam_1572, retro_cfam_1656, retro_cfam_1669, retro_cfam_1900, retro_cfam_1955, retro_cfam_2121, retro_cfam_248,
Callithrix jacchus	ENSCJAG00000000069	1 retrocopy	retro_cjac_340,
Cavia porcellus	ENSCPOG00000015145	1 retrocopy	retro_cpor_534,
Danio rerio	ENSDARG00000053058	1 retrocopy	retro_drer_15,
Equus caballus	ENSECAG00000000370	1 retrocopy	retro_ecab_868,
Erinaceus europaeus	ENSEEUG00000003392	1 retrocopy	retro_eeur_75,
Homo sapiens	ENSG00000142534	6 retrocopies	retro_hsap_1017, retro_hsap_1068, retro_hsap_230, retro_hsap_2449, retro_hsap_4242, retro_hsap_4674,
Loxodonta africana	ENSLAFG00000016217	2 retrocopies	retro_lafr_622, retro_lafr_658,
Monodelphis domestica	ENSMODG00000013434	7 retrocopies	retro_mdom_1185, retro_mdom_1284, retro_mdom_1421, retro_mdom_1950, retro_mdom_636, retro_mdom_922, retro_mdom_978,
Mustela putorius furo	ENSMPUG00000002599	10 retrocopies	retro_mputfur_1402, retro_mputfur_1507, retro_mputfur_200, retro_mputfur_306, retro_mputfur_345, retro_mputfur_485, retro_mputfur_491, retro_mputfur_626, retro_mputfur_781, retro_mputfur_897,
Otolemur garnettii	ENSOGAG00000004627	7 retrocopies	retro_ogar_1290, retro_ogar_1813, retro_ogar_1910, retro_ogar_2037, retro_ogar_2573, retro_ogar_2640, retro_ogar_840,
Procavia capensis	ENSPCAG00000004146	2 retrocopies	retro_pcap_333, retro_pcap_54,
Pongo abelii	ENSPPYG00000025860	5 retrocopies	retro_pabe_1800, retro_pabe_3396, retro_pabe_3631, retro_pabe_855 , retro_pabe_889,
Pan troglodytes	ENSPTRG00000011299	1 retrocopy	retro_ptro_88,
Rattus norvegicus	ENSRNOG00000020595	18 retrocopies	retro_rnor_1132, retro_rnor_1159, retro_rnor_1261, retro_rnor_1299, retro_rnor_1363, retro_rnor_1414, retro_rnor_1435, retro_rnor_1451, retro_rnor_1635, retro_rnor_1790, retro_rnor_2000, retro_rnor_2647, retro_rnor_385, retro_rnor_394, retro_rnor_538, retro_rnor_737, retro_rnor_835, retro_rnor_989,
Sorex araneus	ENSSARG00000003236	2 retrocopies	retro_sara_11, retro_sara_469,
Ictidomys tridecemlineatus	ENSSTOG00000023443	2 retrocopies	retro_itri_1033, retro_itri_805,
Tupaia belangeri	ENSTBEG00000016677	16 retrocopies	retro_tbel_125, retro_tbel_1361, retro_tbel_1753, retro_tbel_2071, retro_tbel_2207, retro_tbel_2808, retro_tbel_2947, retro_tbel_319, retro_tbel_3401, retro_tbel_3571, retro_tbel_3600, retro_tbel_3742, retro_tbel_449, retro_tbel_604, retro_tbel_801, retro_tbel_836,