RetrogeneDB ID: retro_ogar_497

Retrocopy location

• Organism: Bushbaby (Otolemur garnettii)
• Coordinates: GL873522.1:44514603..44515244(+)
• Located in intron of: ENSOGAG00000008851

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RAN
• Ensembl ID: ENSOGAG00000025046
• Aliases: None
• Description: RAN, member RAS oncogene family [Source:HGNC Symbol;Acc:9846]

Sequence

>retro_ogar_497
ATGGCCACTTAGTGAGAGCCCCGGGTCCATTCATGCTTGTACTGGTTGGTGATGGTCGGACTGGGAGAACTGCATTCATG
AAACACCACTTGACTGGTGAATTTGAGAAGTATGTAGCCACCTTAGGCGTTGAGGTCCATCCCCTTGTGTTCCACAGCAA
CAGAGGACCCATCAAGTTTAATGTATGGGATACAGCTGGCCAGGAGAAATTTGGTAGACTGAGACATGGCTATTATATCC
AGACCCAGTGTGCCATTATAATGTATGATGTAACATAAAGAGTTACTCACAAGAACATTCCTAACTGGCATAGAGATCTG
GTATGAATATGTGAAAACATCCCTATCGTGCTGTGTGGAAACAAAGTGGACATTAAGGACAGGAAAGTGAAGGCAAAATC
TATTGTCTTTCACTGGAAGAAAAATCTTCAGTACTACAACATTTCTGCCAAAAGTAACTACAACTTTGACAAGCCTTTTC
TCTGGCTTGCTGGAGAGCTCACTGGAGACCCTAACTTGGAGTTTGTTGCCACACCTGCTCTTGCCCGGCCAGAGGTGATC
ATGGACCCAGCTCTGGCAGCACAATATGAACATGACCTAGAGGTTGCTCAGACAACTGCGCTCCTGGATGAGGATGATGA
C

Alignment

ORF - retro_ogar_497 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 84.72 %
• Parental protein coverage: 99.54 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MAAQGEPQVQ-FKLVLVGDGGTGKTTFVKRHLTGEFEKKYVATLGVEVHPLVFHTNRGPIKFNVWDTAGQ
          MA...EP.V..F.LVLVGDG.TG.T.F.K.HLTGEFEK.YVATLGVEVHPLVFH.NRGPIKFNVWDTAGQ
Retrocopy MAT**EPRVH<FMLVLVGDGRTGRTAFMKHHLTGEFEK-YVATLGVEVHPLVFHSNRGPIKFNVWDTAGQ

Parental  EKFGGLRDGYYIQAQCAIIMFDVTSRVTYKNVPNWHRDLVRVCENIPIVLCGNKVDIKDRKVKAKSIVFH
          EKFG.LR.GYYIQ.QCAIIM.DVT.RVT.KN.PNWHRDLV..CENIPIVLCGNKVDIKDRKVKAKSIVFH
Retrocopy EKFGRLRHGYYIQTQCAIIMYDVT*RVTHKNIPNWHRDLV*ICENIPIVLCGNKVDIKDRKVKAKSIVFH

Parental  RKKNLQYYDISAKSNYNFEKPFLWLARKLIGDPNLEFVAMPALAPPEVVMDPALAAQYEHDLEVAQTTAL
          .KKNLQYY.ISAKSNYNF.KPFLWLA..L.GDPNLEFVA.PALA.PEV.MDPALAAQYEHDLEVAQTTAL
Retrocopy WKKNLQYYNISAKSNYNFDKPFLWLAGELTGDPNLEFVATPALARPEVIMDPALAAQYEHDLEVAQTTAL

Parental  PDEDDD
          .DEDDD
Retrocopy LDEDDD

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Otolemur garnettii was not studied using RNA-Seq expression data.

ChIP-Seq

Otolemur garnettii was not studied using ChIP-Seq data.

EST

Otolemur garnettii was not studied using EST data.

TSS

Otolemur garnettii was not studied using FANTOM5 data.

Lab

retro_ogar_497 was not experimentally validated.

Homology

Retrocopy orthology:

Otolemur garnettii does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 20 parental genes, and 90 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000004222	4 retrocopies	retro_amel_1119, retro_amel_1625, retro_amel_1631, retro_amel_700,
Callithrix jacchus	ENSCJAG00000003927	8 retrocopies	retro_cjac_1558, retro_cjac_1844, retro_cjac_2509, retro_cjac_2952, retro_cjac_3071, retro_cjac_3107, retro_cjac_4222, retro_cjac_492,
Echinops telfairi	ENSETEG00000011875	18 retrocopies	retro_etel_1051, retro_etel_1161, retro_etel_1351, retro_etel_1365, retro_etel_1584, retro_etel_1673, retro_etel_1878, retro_etel_1896, retro_etel_1915, retro_etel_2141, retro_etel_2150, retro_etel_2189, retro_etel_294, retro_etel_383, retro_etel_409, retro_etel_412, retro_etel_514, retro_etel_813,
Homo sapiens	ENSG00000132341	3 retrocopies	retro_hsap_3126, retro_hsap_3446, retro_hsap_4908,
Gorilla gorilla	ENSGGOG00000015340	4 retrocopies	retro_ggor_2142, retro_ggor_2328, retro_ggor_2556, retro_ggor_3066,
Loxodonta africana	ENSLAFG00000017673	1 retrocopy	retro_lafr_1253,
Macaca mulatta	ENSMMUG00000020927	2 retrocopies	retro_mmul_1990, retro_mmul_2641,
Monodelphis domestica	ENSMODG00000015601	8 retrocopies	retro_mdom_100, retro_mdom_1718, retro_mdom_1990, retro_mdom_543, retro_mdom_580, retro_mdom_806, retro_mdom_814, retro_mdom_969,
Mus musculus	ENSMUSG00000029430	4 retrocopies	retro_mmus_1653, retro_mmus_182, retro_mmus_2029, retro_mmus_265,
Nomascus leucogenys	ENSNLEG00000008282	4 retrocopies	retro_nleu_1565, retro_nleu_2303, retro_nleu_2353, retro_nleu_775,
Ornithorhynchus anatinus	ENSOANG00000006447	1 retrocopy	retro_oana_62,
Oryctolagus cuniculus	ENSOCUG00000026506	2 retrocopies	retro_ocun_1139, retro_ocun_958,
Otolemur garnettii	ENSOGAG00000025046	8 retrocopies	retro_ogar_1482, retro_ogar_1611, retro_ogar_2058, retro_ogar_2560, retro_ogar_2692, retro_ogar_2810, retro_ogar_377, retro_ogar_497 ,
Pongo abelii	ENSPPYG00000005124	3 retrocopies	retro_pabe_2582, retro_pabe_2853, retro_pabe_3815,
Pan troglodytes	ENSPTRG00000005636	4 retrocopies	retro_ptro_1762, retro_ptro_2115, retro_ptro_2338, retro_ptro_3273,
Rattus norvegicus	ENSRNOG00000000938	3 retrocopies	retro_rnor_138, retro_rnor_410, retro_rnor_917,
Sarcophilus harrisii	ENSSHAG00000018018	1 retrocopy	retro_shar_538,
Sus scrofa	ENSSSCG00000009746	3 retrocopies	retro_sscr_1136, retro_sscr_194, retro_sscr_771,
Tursiops truncatus	ENSTTRG00000012732	6 retrocopies	retro_ttru_1481, retro_ttru_204, retro_ttru_387, retro_ttru_439, retro_ttru_792, retro_ttru_892,
Vicugna pacos	ENSVPAG00000008880	3 retrocopies	retro_vpac_436, retro_vpac_589, retro_vpac_85,