RetrogeneDB ID: retro_mmus_2810

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 6:31141981..31142641(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMUSG00000086922
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Psma3
• Ensembl ID: ENSMUSG00000060073
• Aliases: None
• Description: proteasome (prosome, macropain) subunit, alpha type 3 [Source:MGI Symbol;Acc:MGI:104883]

Sequence

>retro_mmus_2810
ACAGCTATTGGGATCAGATGTAAAGATGGTGTTGTGTTTGGGGTAGAAAAACTAGTCCTTTCTAAACTTTATGAAGAAGG
CTCCAATAAACGTCTTTTTAATGTTGATCGACATGTTGGAATGGCAGTTGCAGGTTTGCTGGCAGATGCTCGTTCATTAG
CAGACATAGCGAGAGAAGAAGCATCCAACTTTAGGTCCAACTTCGGCTATAACATTCCTCTAAAACATCTTGCAGACAGA
GTGGCCATGTATGTACACGCCTATACACTCTACAGCGCTGTTAGACCTTTTGGCTGCAGTTTCATGTTGGGGTCTTACAG
TGCGAATGATGGTGCACAGCTCTATATGATCGACCCATCAGGTGTTTCATATGGTTACTGGGGCTGTGCGATTGGCAAAG
CCAGGCAGGCTGCAAAGACAGAGATAGAAAAGCTTCAGATGAAGGAAATGACTTGCCGTGATGTAGTTAAAGAAGTTGCA
AAAATAATTTACATAGTACACGATGAAGTTAAGGATAAAGCTTTTGAACTGGAGCTCAGCTGGGTTGGTGAATTAACTAA
AGGAAGACATGAAATTGTTCCCAAAGACATAAGAGAGGAAGCAGAGAAATATGCCAAGGAATCTTTGAAGGAAGAAGATG
AATCAGATGATGACAATATG

Alignment

ORF - retro_mmus_2810 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 100.0 %
• Parental protein coverage: 86.27 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  TAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGY
          TAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGY
Retrocopy TAIGIRCKDGVVFGVEKLVLSKLYEEGSNKRLFNVDRHVGMAVAGLLADARSLADIAREEASNFRSNFGY

Parental  NIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKT
          NIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKT
Retrocopy NIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSANDGAQLYMIDPSGVSYGYWGCAIGKARQAAKT

Parental  EIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLK
          EIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLK
Retrocopy EIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKAFELELSWVGELTKGRHEIVPKDIREEAEKYAKESLK

Parental  EEDESDDDNM
          EEDESDDDNM
Retrocopy EEDESDDDNM

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.42 RPM	42.68 RPM
SRP007412_cerebellum	0.30 RPM	29.44 RPM
SRP007412_heart	0.37 RPM	29.42 RPM
SRP007412_kidney	0.44 RPM	36.23 RPM
SRP007412_liver	0.41 RPM	48.75 RPM
SRP007412_testis	0.05 RPM	22.55 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_2810 was not detected

EST

No EST(s) were mapped for retro_mmus_2810 retrocopy.

TSS

No TSS is located nearby retro_mmus_2810 retrocopy 5' end.

Lab

retro_mmus_2810 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2810 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 55 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000015287	1 retrocopy	retro_cfam_1331,
Callithrix jacchus	ENSCJAG00000018732	1 retrocopy	retro_cjac_3974,
Dasypus novemcinctus	ENSDNOG00000004077	27 retrocopies	retro_dnov_1089, retro_dnov_1115, retro_dnov_1156, retro_dnov_1240, retro_dnov_1252, retro_dnov_1285, retro_dnov_1347, retro_dnov_1473, retro_dnov_1542, retro_dnov_1604, retro_dnov_1650, retro_dnov_1662, retro_dnov_1783, retro_dnov_1785, retro_dnov_1791, retro_dnov_1880, retro_dnov_1896, retro_dnov_198, retro_dnov_2030, retro_dnov_2125, retro_dnov_2128, retro_dnov_2334, retro_dnov_2507, retro_dnov_2578, retro_dnov_447, retro_dnov_765, retro_dnov_992,
Dipodomys ordii	ENSDORG00000002167	1 retrocopy	retro_dord_402,
Homo sapiens	ENSG00000100567	1 retrocopy	retro_hsap_1348,
Gorilla gorilla	ENSGGOG00000015814	1 retrocopy	retro_ggor_1049,
Macaca mulatta	ENSMMUG00000003509	2 retrocopies	retro_mmul_2187, retro_mmul_564,
Monodelphis domestica	ENSMODG00000007839	1 retrocopy	retro_mdom_544,
Mustela putorius furo	ENSMPUG00000006126	2 retrocopies	retro_mputfur_1549, retro_mputfur_414,
Mus musculus	ENSMUSG00000060073	3 retrocopies	retro_mmus_1277, retro_mmus_1463, retro_mmus_2810 ,
Nomascus leucogenys	ENSNLEG00000013092	1 retrocopy	retro_nleu_1831,
Oryctolagus cuniculus	ENSOCUG00000010316	1 retrocopy	retro_ocun_667,
Otolemur garnettii	ENSOGAG00000000382	2 retrocopies	retro_ogar_1764, retro_ogar_2857,
Ochotona princeps	ENSOPRG00000002835	2 retrocopies	retro_opri_67, retro_opri_991,
Pongo abelii	ENSPPYG00000005855	2 retrocopies	retro_pabe_1120, retro_pabe_339,
Pan troglodytes	ENSPTRG00000006390	1 retrocopy	retro_ptro_923,
Rattus norvegicus	ENSRNOG00000007851	1 retrocopy	retro_rnor_183,
Sorex araneus	ENSSARG00000002670	2 retrocopies	retro_sara_437, retro_sara_573,
Ictidomys tridecemlineatus	ENSSTOG00000013539	1 retrocopy	retro_itri_1317,
Tupaia belangeri	ENSTBEG00000016910	1 retrocopy	retro_tbel_1947,
Tursiops truncatus	ENSTTRG00000013526	1 retrocopy	retro_ttru_545,