RetrogeneDB ID: retro_mmus_2798

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 6:145391446..145392163(+)
• Located in intron of: ENSMUSG00000087204

Retrocopy information

• Ensembl ID: ENSMUSG00000087204
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: Rpl7
• Ensembl ID: ENSMUSG00000043716
• Aliases: Rpl7, Rpl7a, Surf-3
• Description: ribosomal protein L7 [Source:MGI Symbol;Acc:MGI:98073]

Sequence

>retro_mmus_2798
AAAAAGAAGGTTGCCGCTGTGCCAGAAACCCTTAAGAAAAAGCAAAGGAATTTCGCAGAGTTGGAGGTGAATCACCCGAG
GAAGAAGTTTGCCCTGAAGACACTGCGAGAGGGAAGGAGGAAGCTCAGCTGTGAGAAGGCAAGGCACTACCACAAGTATA
GGCAGACATACTGGACTGCGATTCGGATGGCCAGGATGGCAAGGAGAGCTGGGAACTTCAATGTGCCCGCAGAACCAAAA
CTGGCCTTTGTCATCACAATCCGAGGTATCAGAGGAGTAAGCCCAAAAGTCCGCAAGGTAGTGCAGCTTCTTCGTCTTCT
ACAGATCTTCACTGGCACCTTTGTTAAGCTCAACAAGGCTTCAATTATCATGCTGCGGATTGTGGAACCGTACATTGCAC
GGGGGTATCCCAACCTGAAGTCAGTAAACAAGCTCATTTACAAGTGAGGCTATGGCAAAATCAACAAGAAGCGGATCGCC
TTGACAGATAATTCGTTGATTGCTCGATCTCTTGGTACATTTGGCATCGCCTGCATGGAGGATCTAGGTCATGAGATCTA
AACAGCTGGAAAAGGATTCAAGAAAGCAAGTAGCTTCCCGTGGCTTCAAATGACCTTCCCACAAGGTGGAAAGAAGAAAA
ACAGAACTCACGTTGTAGAAGGTGGAGATGCTGGCAACAGGGACGACCAGATAAACAAGCTTATTAGATGGATGAAC

Alignment

ORF - retro_mmus_2798 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.25 %
• Parental protein coverage: 89.26 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KKKVPAVPETLKKKRRNFAELKVKRLRKKFALKTLRKARRKLIYEKAKHYHKEYRQMYRTEIRMARMARK
          KKKV.AVPETLKKK.RNFAEL.V...RKKFALKTLR..RRKL..EKA.HYHK.YRQ.Y.T.IRMARMAR.
Retrocopy KKKVAAVPETLKKKQRNFAELEVNHPRKKFALKTLREGRRKLSCEKARHYHK-YRQTYWTAIRMARMARR

Parental  AGNFYVPAEPKLAFVIRIRGINGVSPKVRKVLQLLRLRQIFNGTFVKLNKASINMLRIVEPYIAWGYPNL
          AGNF.VPAEPKLAFVI.IRGI.GVSPKVRKV.QLLRL.QIF.GTFVKLNKASI.MLRIVEPYIA.GYPNL
Retrocopy AGNFNVPAEPKLAFVITIRGIRGVSPKVRKVVQLLRLLQIFTGTFVKLNKASIIMLRIVEPYIARGYPNL

Parental  KSVNELIYKRGYGKINKKRIALTDNSLIARSLGKFGIICMEDLIHEIYTVGKRFKEANNFLWPFKLSSPR
          KSVN.LIYK.GYGKINKKRIALTDNSLIARSLG.FGI.CMEDL.HEI.T.GK.FK.A..F.W......P.
Retrocopy KSVNKLIYK*GYGKINKKRIALTDNSLIARSLGTFGIACMEDLGHEI*TAGKGFKKASSFPW-LQMTFPQ

Parental  GGMKKKTTHFVEGGDAGNREDQINRLIRRMN
          GG.KK..TH.VEGGDAGNR.DQIN.LIR.MN
Retrocopy GGKKKNRTHVVEGGDAGNRDDQINKLIRWMN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.16 RPM	108.26 RPM
SRP007412_cerebellum	0.09 RPM	87.10 RPM
SRP007412_heart	0.34 RPM	118.08 RPM
SRP007412_kidney	0.06 RPM	156.36 RPM
SRP007412_liver	0.08 RPM	136.76 RPM
SRP007412_testis	20.03 RPM	77.30 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_2798 was not detected

EST

No EST(s) were mapped for retro_mmus_2798 retrocopy.

TSS

No TSS is located nearby retro_mmus_2798 retrocopy 5' end.

Lab

retro_mmus_2798 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2798 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 13 parental genes, and 113 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000020139	22 retrocopies	retro_btau_1088, retro_btau_1231, retro_btau_1367, retro_btau_1381, retro_btau_1422, retro_btau_1434, retro_btau_1468, retro_btau_1548, retro_btau_1559, retro_btau_1616, retro_btau_1627, retro_btau_1784, retro_btau_1814, retro_btau_304, retro_btau_426, retro_btau_622, retro_btau_668, retro_btau_730, retro_btau_750, retro_btau_758, retro_btau_863, retro_btau_879,
Callithrix jacchus	ENSCJAG00000007686	1 retrocopy	retro_cjac_105,
Equus caballus	ENSECAG00000009188	1 retrocopy	retro_ecab_35,
Latimeria chalumnae	ENSLACG00000003571	1 retrocopy	retro_lcha_63,
Macropus eugenii	ENSMEUG00000016319	9 retrocopies	retro_meug_1002, retro_meug_1449, retro_meug_1942, retro_meug_1947, retro_meug_60, retro_meug_760, retro_meug_84, retro_meug_968, retro_meug_99,
Macaca mulatta	ENSMMUG00000005141	1 retrocopy	retro_mmul_129,
Monodelphis domestica	ENSMODG00000007136	4 retrocopies	retro_mdom_1341, retro_mdom_1998, retro_mdom_371, retro_mdom_66,
Mus musculus	ENSMUSG00000043716	15 retrocopies	retro_mmus_1232, retro_mmus_1345, retro_mmus_1631, retro_mmus_2549, retro_mmus_2562, retro_mmus_2798 , retro_mmus_3259, retro_mmus_3305, retro_mmus_3440, retro_mmus_3547, retro_mmus_3552, retro_mmus_3685, retro_mmus_561, retro_mmus_595, retro_mmus_708,
Mus musculus	ENSMUSG00000063888	4 retrocopies	retro_mmus_2359, retro_mmus_3172, retro_mmus_3626, retro_mmus_777,
Otolemur garnettii	ENSOGAG00000003903	2 retrocopies	retro_ogar_15, retro_ogar_225,
Rattus norvegicus	ENSRNOG00000006992	27 retrocopies	retro_rnor_1018, retro_rnor_1174, retro_rnor_1222, retro_rnor_1233, retro_rnor_1307, retro_rnor_1388, retro_rnor_1466, retro_rnor_1580, retro_rnor_1745, retro_rnor_1916, retro_rnor_1944, retro_rnor_2025, retro_rnor_2028, retro_rnor_2100, retro_rnor_2247, retro_rnor_2304, retro_rnor_2347, retro_rnor_2531, retro_rnor_2715, retro_rnor_2765, retro_rnor_2814, retro_rnor_2824, retro_rnor_530, retro_rnor_666, retro_rnor_911, retro_rnor_929, retro_rnor_977,
Tupaia belangeri	ENSTBEG00000002301	1 retrocopy	retro_tbel_2042,
Tarsius syrichta	ENSTSYG00000006100	25 retrocopies	retro_tsyr_1149, retro_tsyr_1200, retro_tsyr_1293, retro_tsyr_1297, retro_tsyr_1403, retro_tsyr_1598, retro_tsyr_1633, retro_tsyr_1850, retro_tsyr_1891, retro_tsyr_191, retro_tsyr_2109, retro_tsyr_2130, retro_tsyr_344, retro_tsyr_421, retro_tsyr_433, retro_tsyr_521, retro_tsyr_589, retro_tsyr_601, retro_tsyr_651, retro_tsyr_724, retro_tsyr_779, retro_tsyr_877, retro_tsyr_930, retro_tsyr_953, retro_tsyr_992,