RetrogeneDB ID: retro_mmus_2631

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 5:21613993..21614494(-)
• Located in intron of: ENSMUSG00000048520

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Zbtb8os
• Ensembl ID: ENSMUSG00000057572
• Aliases: None
• Description: zinc finger and BTB domain containing 8 opposite strand [Source:MGI Symbol;Acc:MGI:1914356]

Sequence

>retro_mmus_2631
ATGGCTCAAGAGGAGGATGATGTTAGAGATTACAATTTGACGGAGGAACAGAAGGCGACCAAGGACAAGTATCCTCCAGT
CAATCGAAAGTATGGATATTTGGATCATACGGCTGATGTCCAGTTACACGCATGGGGAGACACTCTGGAGGAAGCATTTG
AACAGTGTGCCATGGCCATGTTTGGTTACATGACAGATACTGGGACTGTGGAGCCCCTCCGCACCGTGGAAGTAGAAACC
CAAGGGGATGACCTGCAGTTTCTGCTGTTTCACTTTTTGGACGAGTGGCTTTACAAGTTCAGCGCTGATGAGTACTTCAT
ACCCCGGGAAGTGAAAGTACTTAATATTGATCAGAAAAATTTCAAGTTACGATTCATTGGGTGGGGAGAAGAGTTCTCAC
TGTCCAAGCACCCTCAGGGAACAGAAGTCAAGGCAATAACGTACTCAGCAATGCAAGTCTATAATGAAGAGAAGCCAGAA
GTGTTTGTGATCATCGACATT

Alignment

ORF - retro_mmus_2631 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 97.6 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MAQEEEDVRDYNLTEEQKATKDKYPPVNRKYEYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTV
          MAQEE.DVRDYNLTEEQKATKDKYPPVNRKY.YLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTV
Retrocopy MAQEEDDVRDYNLTEEQKATKDKYPPVNRKYGYLDHTADVQLHAWGDTLEEAFEQCAMAMFGYMTDTGTV

Parental  EPLRTVEVETQGDDLQSLLFHFLDEWLYKFSADEYFIPREVKVLNIDQKNFKLRSIGWGEEFSLSKHPQG
          EPLRTVEVETQGDDLQ.LLFHFLDEWLYKFSADEYFIPREVKVLNIDQKNFKLR.IGWGEEFSLSKHPQG
Retrocopy EPLRTVEVETQGDDLQFLLFHFLDEWLYKFSADEYFIPREVKVLNIDQKNFKLRFIGWGEEFSLSKHPQG

Parental  TEVKAITYSAMQVYNEEKPEVFVIIDI
          TEVKAITYSAMQVYNEEKPEVFVIIDI
Retrocopy TEVKAITYSAMQVYNEEKPEVFVIIDI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.09 RPM	9.11 RPM
SRP007412_cerebellum	0.13 RPM	13.07 RPM
SRP007412_heart	0.03 RPM	7.07 RPM
SRP007412_kidney	0.17 RPM	20.75 RPM
SRP007412_liver	0.22 RPM	21.63 RPM
SRP007412_testis	1.28 RPM	28.13 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_2631 was not detected

EST

No EST(s) were mapped for retro_mmus_2631 retrocopy.

TSS

No TSS is located nearby retro_mmus_2631 retrocopy 5' end.

Lab

retro_mmus_2631 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_2631 has 0 orthologous retrocopies within eutheria group .

---

Parental genes homology:

Parental genes homology involve 16 parental genes, and 27 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000010550	1 retrocopy	retro_cfam_2152,
Choloepus hoffmanni	ENSCHOG00000004061	2 retrocopies	retro_chof_1005, retro_chof_1158,
Cavia porcellus	ENSCPOG00000015349	2 retrocopies	retro_cpor_356, retro_cpor_903,
Dasypus novemcinctus	ENSDNOG00000001861	2 retrocopies	retro_dnov_1056, retro_dnov_2193,
Equus caballus	ENSECAG00000020982	1 retrocopy	retro_ecab_610,
Felis catus	ENSFCAG00000000700	1 retrocopy	retro_fcat_703,
Homo sapiens	ENSG00000176261	2 retrocopies	retro_hsap_2396, retro_hsap_2992,
Gorilla gorilla	ENSGGOG00000007519	2 retrocopies	retro_ggor_2072, retro_ggor_231,
Myotis lucifugus	ENSMLUG00000000745	5 retrocopies	retro_mluc_1961, retro_mluc_2533, retro_mluc_2570, retro_mluc_2617, retro_mluc_2622,
Macaca mulatta	ENSMMUG00000009939	1 retrocopy	retro_mmul_1915,
Monodelphis domestica	ENSMODG00000017419	2 retrocopies	retro_mdom_400, retro_mdom_901,
Mus musculus	ENSMUSG00000057572	1 retrocopy	retro_mmus_2631 ,
Oryctolagus cuniculus	ENSOCUG00000000940	1 retrocopy	retro_ocun_492,
Otolemur garnettii	ENSOGAG00000011630	1 retrocopy	retro_ogar_3231,
Pongo abelii	ENSPPYG00000001589	2 retrocopies	retro_pabe_13, retro_pabe_2478,
Tursiops truncatus	ENSTTRG00000014968	1 retrocopy	retro_ttru_1200,