RetrogeneDB ID: retro_mmus_1224

Retrocopy location

• Organism: Mouse (Mus musculus)
• Coordinates: 14:99387491..99387766(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: Ppdpf
• Ensembl ID: ENSMUSG00000016344
• Aliases: Ppdpf, 0610012G23Rik, 2610317A05Rik, 2700038C09Rik, 3110053G12Rik
• Description: pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene [Source:MGI Symbol;Acc:MGI:1913746]

Sequence

>retro_mmus_1224
CTGGGCTCCTCGTTCAGCAATAGCTCTGGTGGAAGTGCCGAGTACCCAGGGGACGCTGTACCCCATTCCCCGGGTCTTCC
CAAAGCCGACCCTGCCACTGGTGGGCCAACTTCTTTTTTCGGGAAATCCACCCTCCCATTCATGACTACAGTGTTGGAGT
CTCCAGAGCGCTCGGCAGAATCCCACCAGGTCTCCAGAAGCCCCGTCACCTTTGGTCTGGCTCCTGAAACCATGAAGAAG
CAGCAGTCATCCATCCTGGCCAGACCAACCCCAGG

Alignment

ORF - retro_mmus_1224 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.16 %
• Parental protein coverage: 80.0 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  LGSSSSSSSGGSAEYPGDAVLQSPGLPKADPG-HWWASF-FFGKSTLPFMTTVLESPERSAESPQVSRSP
          LGSS.S.SSGGSAEYPGDAV..SPGLPKADP..HWWA.F.FFGKSTLPFMTTVLESPERSAES.QVSRSP
Retrocopy LGSSFSNSSGGSAEYPGDAVPHSPGLPKADPA<HWWANF>FFGKSTLPFMTTVLESPERSAESHQVSRSP

Parental  MTCGLTPETMKQQ-PVIHSGQTNPR
          .T.GL.PETMK.Q..VIH.GQTNPR
Retrocopy VTFGLAPETMKKQ<AVIHPGQTNPR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.02 RPM	10.40 RPM
SRP007412_cerebellum	0.00 RPM	5.91 RPM
SRP007412_heart	0.00 RPM	8.90 RPM
SRP007412_kidney	0.00 RPM	5.85 RPM
SRP007412_liver	0.00 RPM	10.46 RPM
SRP007412_testis	0.00 RPM	0.73 RPM

ChIP-Seq

RNA Polymerase II activity near the 5' end of retro_mmus_1224 was not detected

EST

No EST(s) were mapped for retro_mmus_1224 retrocopy.

TSS

No TSS is located nearby retro_mmus_1224 retrocopy 5' end.

Lab

retro_mmus_1224 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmus_1224 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 56 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000031800	7 retrocopies	retro_btau_1339, retro_btau_1538, retro_btau_1606, retro_btau_1817, retro_btau_1857, retro_btau_385, retro_btau_54,
Equus caballus	ENSECAG00000009413	1 retrocopy	retro_ecab_477,
Felis catus	ENSFCAG00000024386	14 retrocopies	retro_fcat_1018, retro_fcat_1061, retro_fcat_128, retro_fcat_1293, retro_fcat_1581, retro_fcat_1669, retro_fcat_1685, retro_fcat_194, retro_fcat_308, retro_fcat_325, retro_fcat_355, retro_fcat_440, retro_fcat_711, retro_fcat_789,
Homo sapiens	ENSG00000125534	1 retrocopy	retro_hsap_3205,
Latimeria chalumnae	ENSLACG00000002835	1 retrocopy	retro_lcha_69,
Loxodonta africana	ENSLAFG00000026496	2 retrocopies	retro_lafr_1082, retro_lafr_251,
Macaca mulatta	ENSMMUG00000006064	2 retrocopies	retro_mmul_2020, retro_mmul_41,
Monodelphis domestica	ENSMODG00000016871	2 retrocopies	retro_mdom_1325, retro_mdom_222,
Mustela putorius furo	ENSMPUG00000008301	12 retrocopies	retro_mputfur_1039, retro_mputfur_1097, retro_mputfur_1247, retro_mputfur_1282, retro_mputfur_1312, retro_mputfur_1327, retro_mputfur_1355, retro_mputfur_347, retro_mputfur_526, retro_mputfur_665, retro_mputfur_788, retro_mputfur_928,
Mus musculus	ENSMUSG00000016344	3 retrocopies	retro_mmus_1224 , retro_mmus_658, retro_mmus_815,
Nomascus leucogenys	ENSNLEG00000010068	3 retrocopies	retro_nleu_1154, retro_nleu_1270, retro_nleu_1339,
Otolemur garnettii	ENSOGAG00000008810	2 retrocopies	retro_ogar_1797, retro_ogar_1912,
Pan troglodytes	ENSPTRG00000013739	1 retrocopy	retro_ptro_2243,
Rattus norvegicus	ENSRNOG00000012722	1 retrocopy	retro_rnor_752,
Sarcophilus harrisii	ENSSHAG00000018338	3 retrocopies	retro_shar_637, retro_shar_640, retro_shar_733,
Ictidomys tridecemlineatus	ENSSTOG00000007808	1 retrocopy	retro_itri_1363,