RetrogeneDB ID: retro_ggor_762

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 11:132219815..132220448(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024252
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: CNN2
• Ensembl ID: ENSGGOG00000028153
• Aliases: None
• Description: None

Sequence

>retro_ggor_762
ACCTACGGCATGAACCCCGTGGACCTGTTTGAGGCCAACGATCTGTCTGAGAGTGGGAACACGATGCAGGTGCAGGTGTC
TCTTCTCGTCCTGGCAGGGAAGACTAAGGGGCTGCAGAGCGGGGCGGACATCGGTGACACGCACTCGGAGAAGCAGGAGT
GGGACTTTGAGGACGCCACCATGAATGCCTGCCAGTGCGTCATCGGGCAGCAGATGGGCACCCACAAATGCACCAGCCAG
TCCCGCATGACCGCGTACAGCACGAGGAGGCATCTCTATGACCCCAAGAACCACGTACTGCCTCCCATGGACCACTCGAC
CATCAGCCTCCAGATGGGTGCAAACAAGTGCGCCAGCCAGGTGGGCACGACGGCTCCCGGGACCCGGCGGTACATCTATG
ACACCAAGCTGGGAACCGACAAGTGTAACAACTCGTTCATGTCCCTGCAGATGGGCTACACGCAGGGCGCCAACCAGAGC
GGCCGGGTCTTTGGCCTGGGCCTGCAGATATACGACCCCAAGTACTGCCCGCAAGGCCCAGTGGCCGATGGGGCTCCCTC
GGGTGCAGGCGACCGTCCTGGCCCTGGGGAGGCCCCTGAATATTCCCCTTACTACGAGGAGGAGACTGGCTAC

Alignment

ORF - retro_ggor_762 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.63 %
• Parental protein coverage: 68.93 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  SYGMNPVDLFEANDLFESGNMTQVQVSLLALAGKAKTKGLQSGVDIGVKYSEKQERNFDDATMKAGQCVI
          .YGMNPVDLFEANDL.ESGN..QVQVSLL.LAGK..TKGLQSG.DIG...SEKQE..F.DATM.A.QCVI
Retrocopy TYGMNPVDLFEANDLSESGNTMQVQVSLLVLAGK--TKGLQSGADIGDTHSEKQEWDFEDATMNACQCVI

Parental  GLQMGTNKCASQSGMTAYGTRRHLYDPKNHILPPMDHSTISLQMGTNKCASQVGMTAPGTRRHIYDTKLG
          G.QMGT.KC.SQS.MTAY.TRRHLYDPKNH.LPPMDHSTISLQMG.NKCASQVG.TAPGTRR.IYDTKLG
Retrocopy GQQMGTHKCTSQSRMTAYSTRRHLYDPKNHVLPPMDHSTISLQMGANKCASQVGTTAPGTRRYIYDTKLG

Parental  TDKCDNSSMSLQMGYTQGANQSGQVFGLGRQIYDPKYCPQGTVADGAPSGTGDCPDPGEVPEYPPYYQEE
          TDKC.NS.MSLQMGYTQGANQSG.VFGLG.QIYDPKYCPQG.VADGAPSG.GD.P.PGE.PEY.PYY.EE
Retrocopy TDKCNNSFMSLQMGYTQGANQSGRVFGLGLQIYDPKYCPQGPVADGAPSGAGDRPGPGEAPEYSPYYEEE

Parental  AGY
          .GY
Retrocopy TGY

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	7.82 RPM
SRP007412_cerebellum	0.04 RPM	5.12 RPM
SRP007412_heart	0.00 RPM	32.30 RPM
SRP007412_kidney	0.00 RPM	44.49 RPM
SRP007412_liver	0.00 RPM	54.07 RPM
SRP007412_testis	0.00 RPM	10.26 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_762 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_762 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_943
Pan troglodytes	retro_ptro_653
Macaca mulatta	retro_mmul_1131

---

Parental genes homology:

Parental genes homology involve 13 parental genes, and 53 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000020764	1 retrocopy	retro_btau_612,
Dipodomys ordii	ENSDORG00000001141	1 retrocopy	retro_dord_672,
Erinaceus europaeus	ENSEEUG00000015171	1 retrocopy	retro_eeur_581,
Homo sapiens	ENSG00000064666	16 retrocopies	retro_hsap_1168, retro_hsap_1575, retro_hsap_1697, retro_hsap_2127, retro_hsap_2495, retro_hsap_255, retro_hsap_2576, retro_hsap_2764, retro_hsap_3505, retro_hsap_4168, retro_hsap_4170, retro_hsap_4175, retro_hsap_4257, retro_hsap_4269, retro_hsap_4326, retro_hsap_943,
Gorilla gorilla	ENSGGOG00000013870	1 retrocopy	retro_ggor_2312,
Gorilla gorilla	ENSGGOG00000028153	9 retrocopies	retro_ggor_1199, retro_ggor_1271, retro_ggor_1555, retro_ggor_1612, retro_ggor_1646, retro_ggor_1922, retro_ggor_2370, retro_ggor_305, retro_ggor_762 ,
Myotis lucifugus	ENSMLUG00000013160	4 retrocopies	retro_mluc_1536, retro_mluc_1965, retro_mluc_2047, retro_mluc_2210,
Macaca mulatta	ENSMMUG00000015306	1 retrocopy	retro_mmul_1131,
Mus musculus	ENSMUSG00000004665	2 retrocopies	retro_mmus_1824, retro_mmus_2317,
Nomascus leucogenys	ENSNLEG00000001161	2 retrocopies	retro_nleu_1757, retro_nleu_2893,
Otolemur garnettii	ENSOGAG00000010144	2 retrocopies	retro_ogar_1416, retro_ogar_1733,
Pongo abelii	ENSPPYG00000009302	12 retrocopies	retro_pabe_1299, retro_pabe_1397, retro_pabe_1838, retro_pabe_1920, retro_pabe_2171, retro_pabe_2249, retro_pabe_2900, retro_pabe_3512, retro_pabe_3515, retro_pabe_3543, retro_pabe_3823, retro_pabe_407,
Ictidomys tridecemlineatus	ENSSTOG00000028367	1 retrocopy	retro_itri_326,