RetrogeneDB ID: retro_ggor_1844

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 3:43024370..43024867(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GEMIN2
• Ensembl ID: ENSGGOG00000016691
• Aliases: None
• Description: None

Sequence

>retro_ggor_1844
TTGAAAAGGAAGCAAAGTGTTAATATTTTTCTTTCAGGATGCCAACCAGCCACTGAGGGTTATTCCCCAACACTTCGGTG
GCAACAGCAACAAGTGGCACTGTTTTCAACTATTCGACAGAATGTGAACAAACATAGAAGTCACTGGAAATCACAACAGT
TGGATAGTAATGTGACTATGCCAAAATCTGAAGATGAAGAAGGCTGGAAGAAATTTTCTCTGGGTGAAAAGTTATGTGCT
GACGGGGTTGTTGGATCAGCCACAGTTGAAAGTCCCGGAGTAGATTCTGCACAAGGAAGATGCTTTATGCTTTATTAACT
TGTCTGGAAAAGCCTTTATTACCTCAGGCTCATTCATTGATTCGGCAGCTTGCAAGGTGTTCTGAAGTGAGGCTCTTAGG
GGAGAGCAAAGATGATGAGAAGGTTCCTGCTTTGAATTTATTAGTTTGCTTGCTTAGCAGGTATTTTGACCAATGTGATT
TAGTTGATGAGCCATCT

Alignment

ORF - retro_ggor_1844 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.71 %
• Parental protein coverage: 69.01 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  LKRKQSVNISLSGCQPAPEGYSPTLQWQQQQVAQFSTVRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWK
          LKRKQSVNI.LSGCQPA.EGYSPTL.WQQQQVA.FST.RQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWK
Retrocopy LKRKQSVNIFLSGCQPATEGYSPTLRWQQQQVALFSTIRQNVNKHRSHWKSQQLDSNVTMPKSEDEEGWK

Parental  KFCLGEKLCADGAVGPATNESPGIDYVQGR-WLYALLACLEKPLLPEAHSLIRQLARRCSEVRLLVDSKD
          KF.LGEKLCADG.VG.AT.ESPG.D..QGR..LYALL.CLEKPLLP.AHSLIRQLA.RCSEVRLL..SKD
Retrocopy KFSLGEKLCADGVVGSATVESPGVDSAQGR<MLYALLTCLEKPLLPQAHSLIRQLA-RCSEVRLLGESKD

Parental  DERVPALNLLICLVSRYFDQRDLADEPS
          DE.VPALNLL.CL.SRYFDQ.DL.DEPS
Retrocopy DEKVPALNLLVCLLSRYFDQCDLVDEPS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	3.40 RPM
SRP007412_cerebellum	0.00 RPM	4.22 RPM
SRP007412_heart	0.00 RPM	1.34 RPM
SRP007412_kidney	0.00 RPM	3.27 RPM
SRP007412_liver	0.00 RPM	2.27 RPM
SRP007412_testis	0.00 RPM	10.26 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1844 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1844 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000016248	1 retrocopy	retro_cjac_2630,
Dasypus novemcinctus	ENSDNOG00000018278	1 retrocopy	retro_dnov_1040,
Homo sapiens	ENSG00000092208	1 retrocopy	retro_hsap_455,
Gorilla gorilla	ENSGGOG00000016691	2 retrocopies	retro_ggor_1844 , retro_ggor_438,
Microcebus murinus	ENSMICG00000004811	1 retrocopy	retro_mmur_1221,
Myotis lucifugus	ENSMLUG00000002619	1 retrocopy	retro_mluc_1005,
Mus musculus	ENSMUSG00000060121	1 retrocopy	retro_mmus_354,
Pongo abelii	ENSPPYG00000005764	1 retrocopy	retro_pabe_278,
Pan troglodytes	ENSPTRG00000006291	1 retrocopy	retro_ptro_342,