RetrogeneDB ID: retro_fcat_422

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: A3:32458951..32459442(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSFCAG00000029904
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: SOD1
• Ensembl ID: ENSFCAG00000002225
• Aliases: None
• Description: superoxide dismutase 1, soluble [Source:HGNC Symbol;Acc:11179]

Sequence

>retro_fcat_422
AGCCCTTGAAGCTCGGACCGGACCCCGAGAGTCATGGAGATGAAGGCCGTGTGCGTGCTGAAGGGCCAGGGCCCGGTGGA
GGGCACCATCCACTTCGTACAGAAGGGCAATGGGCCTGTTGTGGTATCAGGAACCATTACAGGATTGACTGAAGGAGAGC
ATGGATTCCACGTCCATCAGTTTGGAGATAATACACAAGGCTGTACCAGTGCAGGCCCTCACTTTAATCCTCTATCCAAA
AAACATGGTGGGCCAAAAGATCAAGAGAGGCATGTTGGAGACCTTGGCAACGTAACTGCTGGCAAGGACGGTGTGGCCAA
CGTGTCTATGGAAGATTCTCTGATTGCACTCTCAGGAGACCATTCCATCATTGGCCGCACGATGGTGTCCACGAGAAACG
AGATGACTTGGGCAAAGGTGGAAATGAAGAAAGTACGCAAACGGGAAACGCTGGGAGTCGTTTGGCTTGTGGTGTCATTG
GGATCGCCAAG

Alignment

ORF - retro_fcat_422 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.19 %
• Parental protein coverage: 100.0 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  SPRSSDRTPRVMEMKAVCVLKGQGPVEGTIHFVQKAGNGPVVVSGTITGLTEGEHGFHVHQFGDNTQGCT
          SP.SSDRTPRVMEMKAVCVLKGQGPVEGTIHFVQK.GNGPVVVSGTITGLTEGEHGFHVHQFGDNTQGCT
Retrocopy SP*SSDRTPRVMEMKAVCVLKGQGPVEGTIHFVQK-GNGPVVVSGTITGLTEGEHGFHVHQFGDNTQGCT

Parental  SAGPHFNPLSKKHGGPKDQERHVGDLGNVTAGKDGVANVSMEDSLIALSGDHSIIGRTMV-VHEKRDDLG
          SAGPHFNPLSKKHGGPKDQERHVGDLGNVTAGKDGVANVSMEDSLIALSGDHSIIGRTMV.VHEKRDDLG
Retrocopy SAGPHFNPLSKKHGGPKDQERHVGDLGNVTAGKDGVANVSMEDSLIALSGDHSIIGRTMV<VHEKRDDLG

Parental  KGGNEESTQTGNAGSRLACGVIGIAK
          KGGNEESTQTGNAGSRLACGVIGIAK
Retrocopy KGGNEESTQTGNAGSRLACGVIGIAK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	8.15 RPM	25.48 RPM
SRP017611_kidney	20.71 RPM	96.67 RPM
SRP017611_liver	19.41 RPM	75.01 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_422 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_422 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 26 parental genes, and 65 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000018854	1 retrocopy	retro_btau_40,
Canis familiaris	ENSCAFG00000008859	1 retrocopy	retro_cfam_1515,
Callithrix jacchus	ENSCJAG00000008983	3 retrocopies	retro_cjac_1477, retro_cjac_1986, retro_cjac_652,
Dasypus novemcinctus	ENSDNOG00000006512	1 retrocopy	retro_dnov_816,
Dipodomys ordii	ENSDORG00000013850	3 retrocopies	retro_dord_217, retro_dord_41, retro_dord_603,
Erinaceus europaeus	ENSEEUG00000015905	1 retrocopy	retro_eeur_305,
Felis catus	ENSFCAG00000002225	2 retrocopies	retro_fcat_1260, retro_fcat_422 ,
Homo sapiens	ENSG00000142168	3 retrocopies	retro_hsap_1637, retro_hsap_3591, retro_hsap_4117,
Gorilla gorilla	ENSGGOG00000015554	4 retrocopies	retro_ggor_1238, retro_ggor_2421, retro_ggor_2690, retro_ggor_2763,
Latimeria chalumnae	ENSLACG00000013736	1 retrocopy	retro_lcha_51,
Loxodonta africana	ENSLAFG00000010708	1 retrocopy	retro_lafr_127,
Microcebus murinus	ENSMICG00000005253	2 retrocopies	retro_mmur_378, retro_mmur_573,
Macaca mulatta	ENSMMUG00000001711	2 retrocopies	retro_mmul_1563, retro_mmul_2372,
Monodelphis domestica	ENSMODG00000021041	1 retrocopy	retro_mdom_1376,
Mus musculus	ENSMUSG00000022982	1 retrocopy	retro_mmus_2742,
Nomascus leucogenys	ENSNLEG00000003545	3 retrocopies	retro_nleu_1324, retro_nleu_302, retro_nleu_584,
Otolemur garnettii	ENSOGAG00000014646	3 retrocopies	retro_ogar_27, retro_ogar_3364, retro_ogar_702,
Ochotona princeps	ENSOPRG00000007008	1 retrocopy	retro_opri_1190,
Pongo abelii	ENSPPYG00000011354	2 retrocopies	retro_pabe_1353, retro_pabe_3370,
Pan troglodytes	ENSPTRG00000013847	3 retrocopies	retro_ptro_1107, retro_ptro_2431, retro_ptro_2796,
Pteropus vampyrus	ENSPVAG00000005216	2 retrocopies	retro_pvam_281, retro_pvam_563,
Sarcophilus harrisii	ENSSHAG00000004195	1 retrocopy	retro_shar_278,
Ictidomys tridecemlineatus	ENSSTOG00000004434	1 retrocopy	retro_itri_1342,
Tupaia belangeri	ENSTBEG00000007333	4 retrocopies	retro_tbel_2131, retro_tbel_3531, retro_tbel_3611, retro_tbel_429,
Tarsius syrichta	ENSTSYG00000011342	17 retrocopies	retro_tsyr_1055, retro_tsyr_1064, retro_tsyr_1082, retro_tsyr_1112, retro_tsyr_1143, retro_tsyr_1176, retro_tsyr_1262, retro_tsyr_1275, retro_tsyr_1295, retro_tsyr_1369, retro_tsyr_1378, retro_tsyr_1590, retro_tsyr_2107, retro_tsyr_365, retro_tsyr_402, retro_tsyr_823, retro_tsyr_831,
Vicugna pacos	ENSVPAG00000012396	1 retrocopy	retro_vpac_168,