RetrogeneDB ID: retro_ecab_449

Retrocopy location

• Organism: Horse (Equus caballus)
• Coordinates: 18:51153754..51154079(-)
• Located in intron of: ENSECAG00000011218

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PDAP1
• Ensembl ID: ENSECAG00000024426
• Aliases: None
• Description: PDGFA associated protein 1 [Source:HGNC Symbol;Acc:14634]

Sequence

>retro_ecab_449
AAAGGTATAGAAGAGCTCATCAACATCGAGAACCCCAAATGGGTGGCAGAGACAATCAGAAAGGTCATACAACTGGATCT
AGACAGGCCAAGGAGCTTTGAAGGAAAAAACAAGACGACACTGAGAAGAGAAAGCAAGAACATTTCATGAAAATCCATTT
AGCTGGGAAGACAGAGCAGGCCAAGGCTATCTCGCCCGGGTGACAGTCATTCGGAAGTAGCAGCAAGAGGGGCAGGAGGC
TGCCAGGAAGAAAAAAGAAGAGAGGAAAGCAAAAGGTGATGCAACTTTGTCAGGAAATCTAATGCAGTTGCTCACCCTGA
ATAGG

Alignment

ORF - retro_ecab_449 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 62.5 %
• Parental protein coverage: 58.15 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  KGVEGLIDIENPNRVAQTTKKVTQLDLDGP-KELSRREREEIEKQKAKERYMKMHLAGKTEQAKAD-LAR
          KG.E.LI.IENP..VA.T..KV.QLDLD.P.KEL.R......EK.K..E..MK.HLAGKTEQAKA..LAR
Retrocopy KGIEELINIENPKWVAETIRKVIQLDLDRP<KEL*RKKQDDTEKRK-QEHFMKIHLAGKTEQAKAI<LAR

Parental  LAIIRK---QREEAARKKEEERKAKDDATLSGKRMQSLSLNK
          ...IRK......EAARKK.EERKAK.DATLSG..MQ.L.LN.
Retrocopy VTVIRK*QQEGQEAARKKKEERKAKGDATLSGNLMQLLTLNR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP021940_articular_cartilage	0.06 RPM	24.14 RPM
SRP021940_cerebellum	0.00 RPM	38.59 RPM
SRP021940_embryo	0.00 RPM	56.87 RPM
SRP021940_placental_villous	0.00 RPM	30.94 RPM
SRP021940_synovial_membrane	0.00 RPM	29.24 RPM
SRP021940_testis	0.00 RPM	47.45 RPM

ChIP-Seq

Equus caballus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ecab_449 retrocopy.

TSS

Equus caballus was not studied using FANTOM5 data.

Lab

retro_ecab_449 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ecab_449 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 16 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000015838	2 retrocopies	retro_cjac_2676, retro_cjac_2725,
Equus caballus	ENSECAG00000024426	1 retrocopy	retro_ecab_449 ,
Echinops telfairi	ENSETEG00000009926	1 retrocopy	retro_etel_900,
Felis catus	ENSFCAG00000015067	1 retrocopy	retro_fcat_1227,
Homo sapiens	ENSG00000106244	3 retrocopies	retro_hsap_1061, retro_hsap_3210, retro_hsap_3506,
Gorilla gorilla	ENSGGOG00000025196	5 retrocopies	retro_ggor_1776, retro_ggor_1778, retro_ggor_2179, retro_ggor_2371, retro_ggor_837,
Macaca mulatta	ENSMMUG00000001460	2 retrocopies	retro_mmul_1865, retro_mmul_943,
Mus musculus	ENSMUSG00000029623	1 retrocopy	retro_mmus_2581,
Nomascus leucogenys	ENSNLEG00000011017	1 retrocopy	retro_nleu_1158,
Otolemur garnettii	ENSOGAG00000010874	2 retrocopies	retro_ogar_2199, retro_ogar_789,
Ochotona princeps	ENSOPRG00000013615	2 retrocopies	retro_opri_262, retro_opri_512,
Pongo abelii	ENSPPYG00000017375	4 retrocopies	retro_pabe_2659, retro_pabe_2806, retro_pabe_2901, retro_pabe_884,
Pan troglodytes	ENSPTRG00000041711	4 retrocopies	retro_ptro_1711, retro_ptro_2240, retro_ptro_2378, retro_ptro_722,
Ictidomys tridecemlineatus	ENSSTOG00000001679	1 retrocopy	retro_itri_765,
Tupaia belangeri	ENSTBEG00000010152	5 retrocopies	retro_tbel_1365, retro_tbel_3543, retro_tbel_4066, retro_tbel_766, retro_tbel_975,
Tursiops truncatus	ENSTTRG00000003004	1 retrocopy	retro_ttru_1343,