RetrogeneDB ID: retro_chof_749

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_14278:8825..9797(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ADIPOR1
• Ensembl ID: ENSCHOG00000006450
• Aliases: None
• Description: adiponectin receptor 1 [Source:HGNC Symbol;Acc:24040]

Sequence

>retro_chof_749
GCTGAAGAAGAACAAACAGGCCCAGTGTCCCAGCAAGAGGAGGAGGTGTGGGTACTGATATTTCCCCTGCAAGCCCAACA
TGCCATGGAGAAGATGGAGGAGTTTGTATATAAGGTCTGGGAAGGACTTGGAGGGTCATCCCATATGATGTGCTCCCTGA
CTGGCTAAGGACAGTGACTACGTGCTACATGGCCACAGACCACCCAGCCTTCTTTTTGGGCTTGCTTCAAGAGATCTTCT
GCATTCATACAAAAGATGGCAATATCTGGACCCATCTGCTTGGTTTGTGCTGTTTCTCTTTTTGGGAATCTTGACCACGT
TCAGACAAATATGTACTTCACAGCTCTGCTACAGAAGAAGGTGGTTTTGGGGATGTTCTTTTTTGGGTGCAGGTTCTGCC
TCAGTTTCTCTTGGTTCTTGCACACCATCTATTGTCATTCAGAGAAAGTCTCTTGGACTTTTTCCAAACTGGATTATTCA
GAGATTGCTCTACTGGTTATGCGGAGCTTTGTCTCCTGGTTCTATTACTCCTTCTACTGCTCCCCACAGCCACAGCTCGT
CTACCTCTCCATAGTCTGTGTCCTGGGGATTTCTGCCATCATTACAGCACAGGGGGACCAGTTTACCACTTCTAAGCACT
GGCAGATGAGAGCAGGAGTGTTCCTGGCACTTGGCTTGAGTGGTGTTGTGCCCACCATGCACTTAACCATTATCGAGGGC
TTTGTCGAGGCCACCTCAGGGGGTCAGGTGGGCTGCTTCTTCCTCACAGCTGTGACGTATGTCACCAGAGCTTGCCTTTA
TGCTGCTAGAATGCCTCAGCACTTCTTTCCTGGGAAATTTGACATATGGTTCCAAGCTCATCAGATTTTTCATGTCCCAC
TGGTTGTAGCTCCCTTTGTACACATCTATGGCGTCTCCAATCTTTAGGAATTCTCTTATGCCCTAGAAGGTGGCTGTTCT
GATGACTCCCTT

Alignment

ORF - retro_chof_749 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 76.58 %
• Parental protein coverage: 88.14 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 6

Retrocopy - Parental Gene Alignment:

Parental  AEEEQTCPVPQEEEEEVRVLTLPLQAHHAMEKMEEFVYKVWEG-RWRVIPYDVLPDWL-KDNDYLLHGHR
          AEEEQT.PV.Q.EEE.V.VL..PLQA.HAMEKMEEFVYKVWEG..WRVIPYDVLPDWL.KD.DY.LHGHR
Retrocopy AEEEQTGPVSQQEEE-VWVLIFPLQAQHAMEKMEEFVYKVWEG<TWRVIPYDVLPDWL<KDSDYVLHGHR

Parental  PP-MPSFRACFK-SIFRIHTETGNIWTHLLG-FVLFLFLGILTMLRP-NMYFMAPLQEKVVFGMFFLGAV
          PP..PSF.ACFK..IF.IHT..GNIWTHLLG.FVLFLFLGILT..R..NMYF.A.LQ.KVV.GMFF.G..
Retrocopy PP<QPSFWACFK<EIFCIHTKDGNIWTHLLG<FVLFLFLGILTTFRQ<NMYFTALLQKKVVLGMFFFGCR

Parental  LCLSFSWLFHTVYCHSEKVSRTFSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAII
          .CLSFSW..HT.YCHSEKVS.TFSKLDYS.IALL.M.SFV.W.YYSFYCSPQP.L.YLSIVCVLGISAII
Retrocopy FCLSFSWFLHTIYCHSEKVSWTFSKLDYSEIALLVMRSFVSWFYYSFYCSPQPQLVYLSIVCVLGISAII

Parental  VAQWDRFATPKHRQTRAGVFLGLGLSGVVPTMHFTIAEGFVKATTVGQMGWFFLMAVMYITGAGLYAARI
          .AQ.D.F.T.KH.Q.RAGVFL.LGLSGVVPTMH.TI.EGFV.AT..GQ.G.FFL.AV.Y.T.A.LYAAR.
Retrocopy TAQGDQFTTSKHWQMRAGVFLALGLSGVVPTMHLTIIEGFVEATSGGQVGCFFLTAVTYVTRACLYAARM

Parental  PERFFPGKFDIWFQSHQIFHVLVVAAAFVHFYGVSNLQEFRYGLEGGCTDDSL
          P..FFPGKFDIWFQ.HQIFHV..V.A.FVH.YGVSNL.EF.Y.LEGGC.DDSL
Retrocopy PQHFFPGKFDIWFQAHQIFHVPLVVAPFVHIYGVSNL*EFSYALEGGCSDDSL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_749 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 42 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012199	1 retrocopy	retro_amel_1853,
Choloepus hoffmanni	ENSCHOG00000006450	8 retrocopies	retro_chof_1127, retro_chof_1222, retro_chof_1917, retro_chof_2218, retro_chof_2380, retro_chof_471, retro_chof_749 , retro_chof_995,
Choloepus hoffmanni	ENSCHOG00000012668	1 retrocopy	retro_chof_1133,
Callithrix jacchus	ENSCJAG00000006268	3 retrocopies	retro_cjac_2262, retro_cjac_740, retro_cjac_741,
Cavia porcellus	ENSCPOG00000000482	1 retrocopy	retro_cpor_470,
Dipodomys ordii	ENSDORG00000006876	1 retrocopy	retro_dord_19,
Felis catus	ENSFCAG00000013565	1 retrocopy	retro_fcat_1514,
Loxodonta africana	ENSLAFG00000003520	1 retrocopy	retro_lafr_277,
Macropus eugenii	ENSMEUG00000015439	1 retrocopy	retro_meug_516,
Microcebus murinus	ENSMICG00000007942	3 retrocopies	retro_mmur_1199, retro_mmur_184, retro_mmur_764,
Myotis lucifugus	ENSMLUG00000016102	2 retrocopies	retro_mluc_1275, retro_mluc_200,
Macaca mulatta	ENSMMUG00000007046	1 retrocopy	retro_mmul_1322,
Mustela putorius furo	ENSMPUG00000011215	1 retrocopy	retro_mputfur_550,
Otolemur garnettii	ENSOGAG00000033821	4 retrocopies	retro_ogar_1558, retro_ogar_1624, retro_ogar_2838, retro_ogar_783,
Ochotona princeps	ENSOPRG00000004528	3 retrocopies	retro_opri_101, retro_opri_1050, retro_opri_392,
Pongo abelii	ENSPPYG00000000342	1 retrocopy	retro_pabe_1072,
Sorex araneus	ENSSARG00000007680	1 retrocopy	retro_sara_25,
Ictidomys tridecemlineatus	ENSSTOG00000015459	3 retrocopies	retro_itri_215, retro_itri_257, retro_itri_512,
Tupaia belangeri	ENSTBEG00000015149	2 retrocopies	retro_tbel_1501, retro_tbel_1804,
Tarsius syrichta	ENSTSYG00000001491	1 retrocopy	retro_tsyr_125,
Tursiops truncatus	ENSTTRG00000006381	2 retrocopies	retro_ttru_1055, retro_ttru_863,