RetrogeneDB ID: retro_chof_1222

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_23023:8268..9023(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ADIPOR1
• Ensembl ID: ENSCHOG00000006450
• Aliases: None
• Description: adiponectin receptor 1 [Source:HGNC Symbol;Acc:24040]

Sequence

>retro_chof_1222
GCTGAAGAAGAGTGAACATGTACAGTGCCCCAGGAAGAAGAGGATGTGGTGTGGGTACTGATAATTCTCCTACAAGCCCA
CCATGCCATGGAGAAGATGGAGGAGTTTATATATAAGATCTTGGAAGGATGTTGGAAGGTCATCCATGTGATGCACTCCC
CAGTTGGCTGAAGTGCAGTGACTACCTGCTACATGGCCATAGACCTCCCAAACCCTCCTTTCCTGCTTCTTTCAAGAGCA
TCTTCTGCATCTATACAAAAACTGGCAGCATTTGGACCCATCTGCTTGTTTCTGTGCTGTTTCCCTTTTTGGGAATCTTG
GCCATACTTAGACCAAACACACACTTCATGAATTCTCTACAGAAGAAGATGGTTTGTGGGATGTTCTTTTTGGGTGCAGT
GCTCTGCCTTAGTTTCTCCTACCTCTTTCACACCATCTATTGTCATTCAGAGAAAGTCTCTTGGACTTTTTTCCAAACTG
GACTCATCAGGGATTTCTCTACAGATTATGGGGACTGTTGTCACCTGCCTCTTTTACCCCTTCTGCTGCTCCCCATAGCC
ATGGCTCATCTACCTCTCTACTGTCTGTGTTCTGGGGATTTCTGCCATCATTATGATGCACTGGGTCCCATTTTCCCCTC
CTAAGCACCTGCAGACAAGGGCAAAATTGTTCCTGGTACTTGGCTTGAGTGGTGGTGTGCCACCATGCACTTTACTACCA
CTGAGGGATTTATTAAAGCCACTAACTGTGGCAGA

Alignment

ORF - retro_chof_1222 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.98 %
• Parental protein coverage: 67.92 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  AEEEQTCPVPQEEEEEVRVLTLPLQAHHAMEKMEEFVYKVWEGRWRVI-PYDVLPDWLKDNDYLLHGHRP
          AEEE.TC.VPQEEE..V.VL...LQAHHAMEKMEEF.YK..EG.W.VI.P.D.LP.WLK..DYLLHGHRP
Retrocopy AEEE*TCTVPQEEEDVVWVLIILLQAHHAMEKMEEFIYKILEGCWKVI<PCDALPSWLKCSDYLLHGHRP

Parental  PMPSFRACFKSIFRIHTETGNIWTHLLGFVLFLFLGILTMLRPNMYFMAPLQEKVVFGMFFLGAVLCLSF
          P.PSF.A.FKSIF.I.T.TG.IWTHLL..VLF.FLGIL..LRPN..FM..LQ.K.V.GMFFLGAVLCLSF
Retrocopy PKPSFPASFKSIFCIYTKTGSIWTHLLVSVLFPFLGILAILRPNTHFMNSLQKKMVCGMFFLGAVLCLSF

Parental  SWLFHTVYCHSEKVSRT-FSKLDYSGIALLIMGSFVPWLYYSFYCSPQPRLIYLSIVCVLGISAIIVAQW
          S.LFHT.YCHSEKVS.T.FSKLD.SGI.L.IMG..V..L.Y.F.CSP.P.LIYLS.VCVLGISAII...W
Retrocopy SYLFHTIYCHSEKVSWT>FSKLDSSGISLQIMGTVVTCLFYPFCCSP*PWLIYLSTVCVLGISAIIMMHW

Parental  DRFATPKHRQTRAGVFLGLGLSGVVP-TMHFTIAEGFVKATTVGQ
          ..F..PKH.QTRA..FL.LGLSG.VP.TMHFT..EGF.KAT..G.
Retrocopy VPFSPPKHLQTRAKLFLVLGLSGGVP<TMHFTTTEGFIKATNCGR

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1222 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 42 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000012199	1 retrocopy	retro_amel_1853,
Choloepus hoffmanni	ENSCHOG00000006450	8 retrocopies	retro_chof_1127, retro_chof_1222 , retro_chof_1917, retro_chof_2218, retro_chof_2380, retro_chof_471, retro_chof_749, retro_chof_995,
Choloepus hoffmanni	ENSCHOG00000012668	1 retrocopy	retro_chof_1133,
Callithrix jacchus	ENSCJAG00000006268	3 retrocopies	retro_cjac_2262, retro_cjac_740, retro_cjac_741,
Cavia porcellus	ENSCPOG00000000482	1 retrocopy	retro_cpor_470,
Dipodomys ordii	ENSDORG00000006876	1 retrocopy	retro_dord_19,
Felis catus	ENSFCAG00000013565	1 retrocopy	retro_fcat_1514,
Loxodonta africana	ENSLAFG00000003520	1 retrocopy	retro_lafr_277,
Macropus eugenii	ENSMEUG00000015439	1 retrocopy	retro_meug_516,
Microcebus murinus	ENSMICG00000007942	3 retrocopies	retro_mmur_1199, retro_mmur_184, retro_mmur_764,
Myotis lucifugus	ENSMLUG00000016102	2 retrocopies	retro_mluc_1275, retro_mluc_200,
Macaca mulatta	ENSMMUG00000007046	1 retrocopy	retro_mmul_1322,
Mustela putorius furo	ENSMPUG00000011215	1 retrocopy	retro_mputfur_550,
Otolemur garnettii	ENSOGAG00000033821	4 retrocopies	retro_ogar_1558, retro_ogar_1624, retro_ogar_2838, retro_ogar_783,
Ochotona princeps	ENSOPRG00000004528	3 retrocopies	retro_opri_101, retro_opri_1050, retro_opri_392,
Pongo abelii	ENSPPYG00000000342	1 retrocopy	retro_pabe_1072,
Sorex araneus	ENSSARG00000007680	1 retrocopy	retro_sara_25,
Ictidomys tridecemlineatus	ENSSTOG00000015459	3 retrocopies	retro_itri_215, retro_itri_257, retro_itri_512,
Tupaia belangeri	ENSTBEG00000015149	2 retrocopies	retro_tbel_1501, retro_tbel_1804,
Tarsius syrichta	ENSTSYG00000001491	1 retrocopy	retro_tsyr_125,
Tursiops truncatus	ENSTTRG00000006381	2 retrocopies	retro_ttru_1055, retro_ttru_863,