RetrogeneDB ID: retro_chof_486

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_113650:4298..4846(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENOPH1
• Ensembl ID: ENSCHOG00000003283
• Aliases: None
• Description: enolase-phosphatase 1 [Source:HGNC Symbol;Acc:24599]

Sequence

>retro_chof_486
GTCATGCTTTCAGTGCCCACAGAAGTCACTGCGATACTATTAGGTATCGAAGGTACCACAACCCTGATGGCTTTCGTGAA
GGGCGTTTTATTTCCTTACATTAAAGTTAATGTTAAAGAGTATCTGCAGACGCATTGGGAAGAAGCGGCATGTCAGCAGT
TTGTCACTCTTTTGAGGAAACAGGCTGAAGAGGATTCCCACCTGGATGCGTTTGTTCCAATCCCTGCAGCATCTCAAAAT
GGGGTGGATGGCCTGCAAAAGATGATCCAAGCTGTGGCAGATAACGTGGACTGGCAGATGTCTCTGGACTGAAGGACCAT
GGCATTGAAACAGGTGCAGGCCAAATGTGGAGGGCGGCATTCACAGCTGAACACATGAAAGCTGAGTTCTTTGAAGATAT
AGTTCCAGCCGTCAAGAAATGGAGACAGGCTGGAATGAAGATATATATCTATTCTTCAGGAAGTGTAGAGGCACAGAAAC
TATTATTTGGGCATTCTACAGAGGGTGATATTTTTGAGCTTGTTGGTGGTCACTCTCATACCAAGATT

Alignment

ORF - retro_chof_486 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 79.89 %
• Parental protein coverage: 70.11 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  VVLSVPAEVTAILLDIEGTTTPIAFVKDILFPYIKENVKEYLQTHWEEEECQQDVSLLRKQAEEDIHLDG
          V.LSVP.EVTAILL.IEGTTT..AFVK..LFPYIK.NVKEYLQTHWEE..CQQ.V.LLRKQAEED.HLD.
Retrocopy VMLSVPTEVTAILLGIEGTTTLMAFVKGVLFPYIKVNVKEYLQTHWEEAACQQFVTLLRKQAEEDSHLDA

Parental  AVPIPAVSGNGVDDLQQMIQAVVDNVCWQMSLDRKTTALKQLQ-GHMWKAAFTAGRMKAEFFEDVVPAVK
          .VPIPA.S.NGVD.LQ.MIQAV.DNV.WQMSLD..T.ALKQ.Q.G.MW.AAFTA..MKAEFFED.VPAVK
Retrocopy FVPIPAASQNGVDGLQKMIQAVADNVDWQMSLD*RTMALKQVQ<GQMWRAAFTAEHMKAEFFEDIVPAVK

Parental  KWREAGMKVYIYSSGSVEAQKLLFGHSTEGDILELVDGHFDTKI
          KWR.AGMK.YIYSSGSVEAQKLLFGHSTEGDI.ELV.GH..TKI
Retrocopy KWRQAGMKIYIYSSGSVEAQKLLFGHSTEGDIFELVGGHSHTKI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_486 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005140	2 retrocopies	retro_amel_1186, retro_amel_930,
Choloepus hoffmanni	ENSCHOG00000003283	4 retrocopies	retro_chof_2150, retro_chof_470, retro_chof_486 , retro_chof_596,
Callithrix jacchus	ENSCJAG00000015251	2 retrocopies	retro_cjac_1376, retro_cjac_2375,
Equus caballus	ENSECAG00000019612	1 retrocopy	retro_ecab_164,
Erinaceus europaeus	ENSEEUG00000004274	1 retrocopy	retro_eeur_563,
Homo sapiens	ENSG00000145293	1 retrocopy	retro_hsap_2900,
Gorilla gorilla	ENSGGOG00000003719	1 retrocopy	retro_ggor_2010,
Loxodonta africana	ENSLAFG00000008619	1 retrocopy	retro_lafr_1158,
Macropus eugenii	ENSMEUG00000011458	1 retrocopy	retro_meug_1125,
Myotis lucifugus	ENSMLUG00000014460	1 retrocopy	retro_mluc_2504,
Otolemur garnettii	ENSOGAG00000002502	1 retrocopy	retro_ogar_1549,
Pongo abelii	ENSPPYG00000014887	1 retrocopy	retro_pabe_2399,
Pan troglodytes	ENSPTRG00000016218	1 retrocopy	retro_ptro_1960,
Ictidomys tridecemlineatus	ENSSTOG00000013987	2 retrocopies	retro_itri_1067, retro_itri_1587,
Tursiops truncatus	ENSTTRG00000001800	1 retrocopy	retro_ttru_1231,