RetrogeneDB ID: retro_chof_2702

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_99065:135..695(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PSAT1
• Ensembl ID: ENSCHOG00000003817
• Aliases: None
• Description: phosphoserine aminotransferase 1 [Source:HGNC Symbol;Acc:19129]

Sequence

>retro_chof_2702
GCCAAGTTGCAGCGCTTGGTATAGTTAGAGATACAGAAAGGATTATTAGAGTACAAAGGAGTTAGGATTAGTGTTCTTGA
AATGACCACAGGTCATCAGATTTTGCTGAGATTATTAACACTACAGAGAATCTGGTGTGGGAATTGTTAACCAATCCAGA
CAACTACAAGGTGATTTTTGTGCAAGGAGGTGGGTCTGGCCAGTTGACTGCTGTCCCCTTAAACCTGTTCTGCTTGAAAG
CAGGAAGATGTGCACACTACGTGGTGACAAAAGCTTGTTCAGCTAAGGCTGCAGAAGCAGCCAAGAAATTTGGGACTGTG
AATACCGTCTACCCCAAACTTGGGAGTTATACAAAAATTCCAGATCCAAGGACCTGGAACCTTAACCCAGACATGCCTGG
TGTGAATGAGACTGTGCAAGCAGTGGAGTTTGATTTTATGCCTGATGTCAAAGGAACAGTGTTGGTTTGTATCATGTCCT
CAAACTTCCTGCCTAAGCCTATGGATGTGTCCAACTTTGGCGTGATTTTTGCTGGTGCTCAGGAGAATGTGGGCTCTGCA

Alignment

ORF - retro_chof_2702 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.96 %
• Parental protein coverage: 50.96 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  AKLPHSVLLEIQKELLDYKEVGISVLEMS-HRSSDFAKIINTTENLVRELLAIPDNYKVIFVQGGGCGQF
          AKL...V.LEIQK.LL.YK.V.ISVLEM..HRSSDFA.IINTTENLV.ELL..PDNYKVIFVQGGG.GQ.
Retrocopy AKLQRLV*LEIQKGLLEYKGVRISVLEMT<HRSSDFAEIINTTENLVWELLTNPDNYKVIFVQGGGSGQL

Parental  SAVPLNLIGLKAARCADYVVTGAWS---AKAAED--TVNTVYPKLGSYTKIPDPSTWNLNPDASYVYYCA
          .AVPLNL..LKA.RCA.YVVT.A.S...A.AA....TVNTVYPKLGSYTKIPDP.TWNLNPD...V....
Retrocopy TAVPLNLFCLKAGRCAHYVVTKACSAKAAEAAKKFGTVNTVYPKLGSYTKIPDPRTWNLNPDMPGV----

Parental  NETVHGVEFDFVPDVKGAVLVCDMSSNFLSKPVDVSKFGVLFAGAQKNVGAA
          NETV..VEFDF.PDVKG.VLVC.MSSNFL.KP.DVS.FGV.FAGAQ.NVG.A
Retrocopy NETVQAVEFDFMPDVKGTVLVCIMSSNFLPKPMDVSNFGVIFAGAQENVGSA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2702 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 28 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000006898	1 retrocopy	retro_amel_375,
Bos taurus	ENSBTAG00000013960	1 retrocopy	retro_btau_1658,
Canis familiaris	ENSCAFG00000001570	1 retrocopy	retro_cfam_269,
Choloepus hoffmanni	ENSCHOG00000003817	1 retrocopy	retro_chof_2702 ,
Callithrix jacchus	ENSCJAG00000003319	1 retrocopy	retro_cjac_1203,
Echinops telfairi	ENSETEG00000004158	1 retrocopy	retro_etel_99,
Homo sapiens	ENSG00000135069	3 retrocopies	retro_hsap_2267, retro_hsap_4054, retro_hsap_412,
Gorilla gorilla	ENSGGOG00000015480	1 retrocopy	retro_ggor_407,
Loxodonta africana	ENSLAFG00000017917	2 retrocopies	retro_lafr_1249, retro_lafr_660,
Macaca mulatta	ENSMMUG00000011868	2 retrocopies	retro_mmul_1029, retro_mmul_2341,
Mustela putorius furo	ENSMPUG00000012566	1 retrocopy	retro_mputfur_808,
Nomascus leucogenys	ENSNLEG00000002989	3 retrocopies	retro_nleu_1010, retro_nleu_1288, retro_nleu_2805,
Oryctolagus cuniculus	ENSOCUG00000007765	1 retrocopy	retro_ocun_1092,
Pongo abelii	ENSPPYG00000019313	3 retrocopies	retro_pabe_1950, retro_pabe_308, retro_pabe_3328,
Pan troglodytes	ENSPTRG00000021045	2 retrocopies	retro_ptro_1606, retro_ptro_316,
Rattus norvegicus	ENSRNOG00000013971	1 retrocopy	retro_rnor_1663,
Tupaia belangeri	ENSTBEG00000012946	1 retrocopy	retro_tbel_1577,
Tarsius syrichta	ENSTSYG00000000093	2 retrocopies	retro_tsyr_1073, retro_tsyr_1212,