RetrogeneDB ID: retro_chof_125

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: GeneScaffold_266:35230..35567(+)
• Located in intron of: ENSCHOG00000005797

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: POLR3G
• Ensembl ID: ENSCHOG00000006306
• Aliases: None
• Description: polymerase (RNA) III (DNA directed) polypeptide G (32kD) [Source:HGNC Symbol;Acc:30075]

Sequence

>retro_chof_125
ATGGCTGGGAATAAAGGAAGAGGGCGTGCTGCTTACACCTTTAACATAGAGGCAGTTGGATTTACCAGAGGTGAGAAGTT
ACCTGATGTCGTATTGAAACCACCCCCACTATTTCCTGATACAGATTATAAACCAGTGCCACTGAAAACAGGAGAAGGTG
AAGATTGTATGCTGGCTTTGAAACAGGAGCTGAGAGAAACAATGAAAAGAATGCCTTTTTTTATGGAAACACCTGAAGAA
AACAGATATTGGAAAGGTATAGTAAAAGATACATGAAGGTATACAAAGAAGAATGGGTACCAGATTGGAGAAGACTCCAA
GAGAGATGATGCCACAG

Alignment

ORF - retro_chof_125 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 93.04 %
• Parental protein coverage: 50.9 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  MAGNKGRGRAAYTFNIEAVGFTRGEKLPDVVLKPPPLFPXXXYKPVPLKTGEGEDYMLALKQELRETMKR
          MAGNKGRGRAAYTFNIEAVGFTRGEKLPDVVLKPPPLFP...YKPVPLKTGEGED.MLALKQELRETMKR
Retrocopy MAGNKGRGRAAYTFNIEAVGFTRGEKLPDVVLKPPPLFPDTDYKPVPLKTGEGEDCMLALKQELRETMKR

Parental  MPFFMETPEE-KQDIERYSKRYMKVYKEEWVPDWRRL-PREMMPQ
          MPFFMETPEE.KQ..ERYSKRYMKVYKEEWVPDWRRL.PREMMPQ
Retrocopy MPFFMETPEE<KQILERYSKRYMKVYKEEWVPDWRRL<PREMMPQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_125 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 14 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000006306	1 retrocopy	retro_chof_125 ,
Callithrix jacchus	ENSCJAG00000010747	1 retrocopy	retro_cjac_2691,
Echinops telfairi	ENSETEG00000008379	1 retrocopy	retro_etel_1040,
Homo sapiens	ENSG00000113356	2 retrocopies	retro_hsap_1454, retro_hsap_1885,
Gorilla gorilla	ENSGGOG00000000266	2 retrocopies	retro_ggor_1119, retro_ggor_1382,
Myotis lucifugus	ENSMLUG00000014954	1 retrocopy	retro_mluc_2233,
Macaca mulatta	ENSMMUG00000018972	1 retrocopy	retro_mmul_1332,
Nomascus leucogenys	ENSNLEG00000013749	1 retrocopy	retro_nleu_1807,
Otolemur garnettii	ENSOGAG00000005560	1 retrocopy	retro_ogar_3512,
Pongo abelii	ENSPPYG00000015624	1 retrocopy	retro_pabe_1564,
Pan troglodytes	ENSPTRG00000017068	2 retrocopies	retro_ptro_1266, retro_ptro_989,
Rattus norvegicus	ENSRNOG00000016260	2 retrocopies	retro_rnor_458, retro_rnor_503,
Ictidomys tridecemlineatus	ENSSTOG00000008664	1 retrocopy	retro_itri_18,
Tupaia belangeri	ENSTBEG00000002278	2 retrocopies	retro_tbel_2495, retro_tbel_3069,