RetrogeneDB ID: retro_btau_418

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 11:5928514..5928732(-)
• Located in intron of: ENSBTAG00000019697

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: TXN
• Ensembl ID: ENSBTAG00000002953
• Aliases: None
• Description: Thioredoxin [Source:UniProtKB/Swiss-Prot;Acc:O97680]

Sequence

>retro_btau_418
GGGACTTGCAAAATGATCAAGGCTTTCTCTCATTCTCTCTCTGAAAAGTGTTCCAATGTGCTGTTCCTCAAAGCAGATGT
GAATGGCCATCAGGATGCTGCTTCACAGTGTGAAGCCAAATGCACACCAACCTTCTAGTTATTTAAAAAGGGACAGAAGG
TGGGTGAATTTTCTGGAGTTACAAGGGAAAACTTGAAGCCACCATTCATGAATTAATC

Alignment

ORF - retro_btau_418 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 70.27 %
• Parental protein coverage: 75.26 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  GPCKMIKPFFHSLSEKYSNVVFLEVDVDDCQDVAAECEVKCMPTFQFFKKGQKVGEFSGANKE-KLEATI
          G.CKMIK.F.HSLSEK.SNV.FL..DV...QD.A..CE.KC.PTF..FKKGQKVGEFSG...E.KLEATI
Retrocopy GTCKMIKAFSHSLSEKCSNVLFLKADVNGHQDAASQCEAKCTPTF*LFKKGQKVGEFSGVTRE<KLEATI

Parental  NELI
          .ELI
Retrocopy HELI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	0.00 RPM	77.43 RPM
ERP005899_muscle	0.05 RPM	102.57 RPM
SRP017611_brain	0.00 RPM	13.52 RPM
SRP017611_kidney	0.06 RPM	48.37 RPM
SRP017611_liver	0.00 RPM	106.54 RPM
SRP030211_testis	0.00 RPM	10.75 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_418 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_418 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_418 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 104 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000013018	3 retrocopies	retro_acar_112, retro_acar_121, retro_acar_122,
Ailuropoda melanoleuca	ENSAMEG00000018017	3 retrocopies	retro_amel_1559, retro_amel_211, retro_amel_217,
Bos taurus	ENSBTAG00000002953	2 retrocopies	retro_btau_1267, retro_btau_418 ,
Choloepus hoffmanni	ENSCHOG00000011506	10 retrocopies	retro_chof_1111, retro_chof_127, retro_chof_1557, retro_chof_1680, retro_chof_1696, retro_chof_240, retro_chof_2424, retro_chof_317, retro_chof_617, retro_chof_82,
Callithrix jacchus	ENSCJAG00000017321	5 retrocopies	retro_cjac_1407, retro_cjac_2536, retro_cjac_2733, retro_cjac_3010, retro_cjac_69,
Cavia porcellus	ENSCPOG00000015348	5 retrocopies	retro_cpor_1048, retro_cpor_49, retro_cpor_54, retro_cpor_55, retro_cpor_74,
Dasypus novemcinctus	ENSDNOG00000019205	20 retrocopies	retro_dnov_100, retro_dnov_1047, retro_dnov_1122, retro_dnov_1222, retro_dnov_1353, retro_dnov_1403, retro_dnov_1404, retro_dnov_1628, retro_dnov_1634, retro_dnov_1646, retro_dnov_1949, retro_dnov_1996, retro_dnov_2069, retro_dnov_2197, retro_dnov_2239, retro_dnov_290, retro_dnov_466, retro_dnov_593, retro_dnov_843, retro_dnov_852,
Equus caballus	ENSECAG00000013324	1 retrocopy	retro_ecab_51,
Echinops telfairi	ENSETEG00000003065	13 retrocopies	retro_etel_1173, retro_etel_1256, retro_etel_1672, retro_etel_1725, retro_etel_1807, retro_etel_1831, retro_etel_1932, retro_etel_1956, retro_etel_320, retro_etel_389, retro_etel_737, retro_etel_903, retro_etel_926,
Felis catus	ENSFCAG00000004790	4 retrocopies	retro_fcat_1096, retro_fcat_1105, retro_fcat_2025, retro_fcat_877,
Gorilla gorilla	ENSGGOG00000006925	6 retrocopies	retro_ggor_1283, retro_ggor_1769, retro_ggor_2440, retro_ggor_35, retro_ggor_401, retro_ggor_620,
Loxodonta africana	ENSLAFG00000012856	2 retrocopies	retro_lafr_372, retro_lafr_93,
Macropus eugenii	ENSMEUG00000003515	8 retrocopies	retro_meug_1198, retro_meug_1204, retro_meug_1603, retro_meug_192, retro_meug_2170, retro_meug_2175, retro_meug_539, retro_meug_840,
Myotis lucifugus	ENSMLUG00000009065	3 retrocopies	retro_mluc_1268, retro_mluc_1940, retro_mluc_776,
Macaca mulatta	ENSMMUG00000010322	1 retrocopy	retro_mmul_167,
Mustela putorius furo	ENSMPUG00000007426	3 retrocopies	retro_mputfur_1230, retro_mputfur_693, retro_mputfur_840,
Procavia capensis	ENSPCAG00000014011	1 retrocopy	retro_pcap_311,
Pongo abelii	ENSPPYG00000019491	2 retrocopies	retro_pabe_1428, retro_pabe_2965,
Pteropus vampyrus	ENSPVAG00000007265	1 retrocopy	retro_pvam_433,
Sorex araneus	ENSSARG00000007465	2 retrocopies	retro_sara_373, retro_sara_525,
Sarcophilus harrisii	ENSSHAG00000006739	1 retrocopy	retro_shar_329,
Sus scrofa	ENSSSCG00000005453	1 retrocopy	retro_sscr_786,
Ictidomys tridecemlineatus	ENSSTOG00000020668	4 retrocopies	retro_itri_6, retro_itri_714, retro_itri_823, retro_itri_884,
Tupaia belangeri	ENSTBEG00000011193	2 retrocopies	retro_tbel_1293, retro_tbel_3405,
Tursiops truncatus	ENSTTRG00000000119	1 retrocopy	retro_ttru_1378,