RetrogeneDB ID: retro_ptro_1019

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 15:54817691..54818103(+)
• Located in intron of: ENSPTRG00000007110

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: HRSP12
• Ensembl ID: ENSPTRG00000020457
• Aliases: None
• Description: None

Sequence

>retro_ptro_1019
ATGCCATCCTTGATCAGAAAGGTGATCAACACTGAGAAAGCCCAAGGGTACACTGGTCCCTTCAGTCAAGCTGCGTTAGT
TGATGGGATCCTTTACATTTCAGGAGAGCTAGGCATGAACCTTTCGAGTGCACAGCTTGTGCCAAGAGTGGGTAACAGAA
GAAGCTAAACAGGCCCTTAAGAACATGGGTGATATTTTGAAAGCTGCAGGCTGTGACTTCACTAATGTGGTAAAAACAAC
TGTTTGGCTAGCTGACACAAATGACTTCAGGGCTGTCAATGTAATCTACAAACAGTATTTTAAGAGTGGTTTTTCTACTA
GAGCTGCTTACCATGTTGCTGCTTTACCCAAAGGAGGCCAGGTTGAAATTGAAGCAGTAGCTGTTCAAGGACCTCTCACA
ACAGCCTGTCTA

Alignment

ORF - retro_ptro_1019 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 73.91 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MSSLIRRVISTAKAPGAIGPYSQAVLVDRTIYISGQIGMDPSSGQLV-SGGVAEEAKQALKNMGEILKAA
          M.SLIR.VI.T.KA.G..GP.SQA.LVD...YISG..GM..SS.QLV....V.EEAKQALKNMG.ILKAA
Retrocopy MPSLIRKVINTEKAQGYTGPFSQAALVDGILYISGELGMNLSSAQLV>QEWVTEEAKQALKNMGDILKAA

Parental  GCDFTNVVKTTVLLADINDFNTVNEIYKQYFKSNFPARAAYQVAALPKGSRIEIEAVAVQGPLTTASL
          GCDFTNVVKTTV.LAD.NDF..VN.IYKQYFKS.F..RAAY.VAALPKG...EIEAVAVQGPLTTA.L
Retrocopy GCDFTNVVKTTVWLADTNDFRAVNVIYKQYFKSGFSTRAAYHVAALPKGGQVEIEAVAVQGPLTTACL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.02 RPM	15.44 RPM
SRP007412_cerebellum	0.00 RPM	5.13 RPM
SRP007412_heart	0.00 RPM	8.19 RPM
SRP007412_kidney	0.16 RPM	168.68 RPM
SRP007412_liver	0.03 RPM	95.13 RPM
SRP007412_testis	0.00 RPM	8.43 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_1019 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_1019 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_1019 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1502
Gorilla gorilla	retro_ggor_1153
Pongo abelii	retro_pabe_1253

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Parental genes homology:

Parental genes homology involve 23 parental genes, and 69 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000000575	1 retrocopy	retro_amel_1033,
Bos taurus	ENSBTAG00000012595	5 retrocopies	retro_btau_1068, retro_btau_1145, retro_btau_1328, retro_btau_771, retro_btau_912,
Canis familiaris	ENSCAFG00000030250	1 retrocopy	retro_cfam_668,
Choloepus hoffmanni	ENSCHOG00000001278	8 retrocopies	retro_chof_133, retro_chof_1972, retro_chof_2434, retro_chof_2503, retro_chof_2676, retro_chof_380, retro_chof_515, retro_chof_757,
Callithrix jacchus	ENSCJAG00000015560	2 retrocopies	retro_cjac_1702, retro_cjac_465,
Dasypus novemcinctus	ENSDNOG00000025138	3 retrocopies	retro_dnov_1155, retro_dnov_224, retro_dnov_793,
Felis catus	ENSFCAG00000002167	1 retrocopy	retro_fcat_624,
Homo sapiens	ENSG00000132541	3 retrocopies	retro_hsap_1502, retro_hsap_284, retro_hsap_3022,
Gorilla gorilla	ENSGGOG00000001185	1 retrocopy	retro_ggor_1153,
Loxodonta africana	ENSLAFG00000002078	1 retrocopy	retro_lafr_437,
Microcebus murinus	ENSMICG00000004356	13 retrocopies	retro_mmur_1096, retro_mmur_1206, retro_mmur_1323, retro_mmur_209, retro_mmur_222, retro_mmur_364, retro_mmur_533, retro_mmur_589, retro_mmur_597, retro_mmur_603, retro_mmur_79, retro_mmur_870, retro_mmur_97,
Macaca mulatta	ENSMMUG00000011825	2 retrocopies	retro_mmul_558, retro_mmul_88,
Monodelphis domestica	ENSMODG00000006575	1 retrocopy	retro_mdom_319,
Mustela putorius furo	ENSMPUG00000015253	1 retrocopy	retro_mputfur_1449,
Nomascus leucogenys	ENSNLEG00000002485	3 retrocopies	retro_nleu_1721, retro_nleu_3065, retro_nleu_837,
Ornithorhynchus anatinus	ENSOANG00000021532	1 retrocopy	retro_oana_33,
Otolemur garnettii	ENSOGAG00000001465	3 retrocopies	retro_ogar_2308, retro_ogar_2951, retro_ogar_552,
Pongo abelii	ENSPPYG00000018776	3 retrocopies	retro_pabe_1253, retro_pabe_2504, retro_pabe_387,
Pan troglodytes	ENSPTRG00000020457	3 retrocopies	retro_ptro_1019 , retro_ptro_2040, retro_ptro_234,
Sus scrofa	ENSSSCG00000006079	1 retrocopy	retro_sscr_834,
Ictidomys tridecemlineatus	ENSSTOG00000011452	4 retrocopies	retro_itri_1591, retro_itri_192, retro_itri_605, retro_itri_894,
Tursiops truncatus	ENSTTRG00000016066	5 retrocopies	retro_ttru_1282, retro_ttru_1589, retro_ttru_1626, retro_ttru_369, retro_ttru_909,
Vicugna pacos	ENSVPAG00000008277	3 retrocopies	retro_vpac_30, retro_vpac_358, retro_vpac_89,