RetrogeneDB ID: retro_pabe_3497

Retrocopy location

• Organism: Orangutan (Pongo abelii)
• Coordinates: 9:97279430..97279914(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: FYTTD1
• Ensembl ID: ENSPPYG00000014456
• Aliases: None
• Description: UAP56-interacting factor [Source:RefSeq peptide;Acc:NP_001126934]

Sequence

>retro_pabe_3497
ACCGGAGCCTGGCAATTCAGGATGAGCATATGATGGAGAATTCAACAGAATTCTGGCTTTGGTAAGACTAGTCTGAGCAC
AGAGGAAGAGTAATGCCTGGAAAGAGACAGCTTTATGGAGTTATCACTGGCCTTGCATCTAGGAAAGCAACTGGAATTCA
CAAAGAAATTAATCCTATGAATCATCCATCTCTAAGTGACAGGAATATAGAACGATATTTTCTAGTGTTAAAAAGGAAGG
CAAACCTTCTGGGACAAATATGAAGTGCAGAAAAAACCAGTTGCAGTTCTCAAGGGACCTAACCAGCTAAACAGAAAAAA
TAACATTCCAGCCAATTTTACCAAGAGTGGAAATAAATTAAGCCATCAGAAGCACATGCGTCAGGCAACTTTTCTTTTCA
GAAGAGACCTGAAGGTGCAGACCCAGTTGAACACAACAGCAACTGCTGGATAATGTAGTAGGAAAGAGAACTCATCAATG
GCAA

Alignment

ORF - retro_pabe_3497 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.39 %
• Parental protein coverage: 50.63 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  SGAQQFRMRVRWGIQQNSGFSKTSLN-RRGRVMPGKRRPNGVITGLAARKTTGIRKGISPMNRPPLSDKN
          .GA.QFRM...W.IQQNSGF.KTSL...RGRVMPGKR...GVITGLA.RK.TGI.K.I.PMN.P.LSD.N
Retrocopy TGAWQFRMSI*WRIQQNSGFGKTSLS<HRGRVMPGKRQLYGVITGLASRKATGIHKEINPMNHPSLSDRN

Parental  IEQYFPVLKRKANLLRQ-NEGQRKPVAVLKRPNQLSRKNNIPANFTRSGNKLNHQKDTRQATFLFRRGLK
          IE.YF.VLKRKANLL.Q..E.Q.KPVAVLK.PNQL.RKNNIPANFT.SGNKL.HQK..RQATFLFRR.LK
Retrocopy IERYFLVLKRKANLLGQ>YEVQKKPVAVLKGPNQLNRKNNIPANFTKSGNKLSHQKHMRQATFLFRRDLK

Parental  VQAQLNT-EQLLDDVVAKRTRQWR
          VQ.QLNT..QLLD.VV.KRT.QW.
Retrocopy VQTQLNT>QQLLDNVVGKRTHQWQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	24.60 RPM
SRP007412_cerebellum	0.12 RPM	62.50 RPM
SRP007412_heart	0.00 RPM	37.96 RPM
SRP007412_kidney	0.03 RPM	28.87 RPM
SRP007412_liver	1.10 RPM	27.42 RPM

ChIP-Seq

Pongo abelii was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_pabe_3497 retrocopy.

TSS

Pongo abelii was not studied using FANTOM5 data.

Lab

retro_pabe_3497 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_pabe_3497 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4291

---

Parental genes homology:

Parental genes homology involve 17 parental genes, and 31 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000014874	1 retrocopy	retro_btau_1572,
Canis familiaris	ENSCAFG00000029695	1 retrocopy	retro_cfam_70,
Choloepus hoffmanni	ENSCHOG00000002881	2 retrocopies	retro_chof_1068, retro_chof_114,
Callithrix jacchus	ENSCJAG00000016488	2 retrocopies	retro_cjac_1639, retro_cjac_623,
Cavia porcellus	ENSCPOG00000011463	2 retrocopies	retro_cpor_1039, retro_cpor_586,
Dasypus novemcinctus	ENSDNOG00000007807	6 retrocopies	retro_dnov_1010, retro_dnov_1224, retro_dnov_1311, retro_dnov_2013, retro_dnov_442, retro_dnov_570,
Erinaceus europaeus	ENSEEUG00000001433	1 retrocopy	retro_eeur_13,
Echinops telfairi	ENSETEG00000000700	1 retrocopy	retro_etel_765,
Homo sapiens	ENSG00000122068	2 retrocopies	retro_hsap_4291, retro_hsap_476,
Gorilla gorilla	ENSGGOG00000011665	1 retrocopy	retro_ggor_450,
Macaca mulatta	ENSMMUG00000006626	1 retrocopy	retro_mmul_577,
Nomascus leucogenys	ENSNLEG00000015547	2 retrocopies	retro_nleu_1047, retro_nleu_889,
Pongo abelii	ENSPPYG00000014456	2 retrocopies	retro_pabe_258, retro_pabe_3497 ,
Pan troglodytes	ENSPTRG00000015796	1 retrocopy	retro_ptro_357,
Sorex araneus	ENSSARG00000009996	1 retrocopy	retro_sara_148,
Sarcophilus harrisii	ENSSHAG00000005704	1 retrocopy	retro_shar_242,
Tupaia belangeri	ENSTBEG00000005595	4 retrocopies	retro_tbel_2469, retro_tbel_2943, retro_tbel_4257, retro_tbel_791,