RetrogeneDB ID: retro_mmul_519

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 1:109418769..109419148(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: OOEP
• Ensembl ID: ENSMMUG00000000416
• Aliases: None
• Description: oocyte expressed protein [Source:HGNC Symbol;Acc:21382]

Sequence

>retro_mmul_519
ACTGAGTCAGGCAAATGGACTCTGTCTCACTACATGGAGAAGCTGCTCAGGTTACCACTTCCCCACCACAGATTCTCATG
GGCTCTGGTGGTTTCTGGTGCAGTAACTGAGAGACCCTTCCATGTTCTACCTGGAGGTATAGCTGGCAGATGCGATCTTT
GAGGTAGACCGAGCCATCTTTCAGGACTGGAGTGGATGAGCCAGTCCCTGTTAATGGTGGACATAGTGGACTCTGGGATC
CAAGTCAAAAATCACAGTTTTTGGACAACTCTGTGTATAGAATCGGGTAAAGACAATGTTCCTGTGCTTGACATGGCTTC
ACCAACAACATCATGCTTAAGCTGAGAAAATAAAACACCCCGAGGAGAACTTGAAAGCC

Alignment

ORF - retro_mmul_519 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 54.96 %
• Parental protein coverage: 94.07 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  SQRGKQTPADSLEQLRMLPLP-PPQIRIRP-WWFPVQELGDPLVFYLEAWLADELFGPDRAMIPE-MEWT
          ...GK.T.....E.L..LPLP.PPQI.....WWF.VQ.L.DP..FYLE..LAD..F..DRA......EW.
Retrocopy TESGKWTLSHYMEKLLRLPLP<PPQILMGS<WWFLVQ*LRDPSMFYLEV*LADAIFEVDRAIFQD<LEWM

Parental  SQALMTVDIVDSGNLV-EITVFGRPSVQNRVKSMLLCLASFHREHRARAEKMKHLEKNLKA
          SQ.L..VDIVDSG..V..ITVFG...V.NRVK.M.LCL...H..H.A.AEK.KH.E.NLKA
Retrocopy SQSLLMVDIVDSGIQV>KITVFGQLCV*NRVKTMFLCLTWLHQQHHA*AEKIKHPEENLKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.00 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.04 RPM	1.73 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_519 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_519 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_519 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_432
Pan troglodytes	retro_ptro_329
Gorilla gorilla	retro_ggor_422
Callithrix jacchus	retro_cjac_3033

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000009962	1 retrocopy	retro_cjac_3033,
Homo sapiens	ENSG00000203907	3 retrocopies	retro_hsap_432, retro_hsap_4807, retro_hsap_543,
Gorilla gorilla	ENSGGOG00000016832	3 retrocopies	retro_ggor_2992, retro_ggor_422, retro_ggor_495,
Loxodonta africana	ENSLAFG00000012754	2 retrocopies	retro_lafr_412, retro_lafr_782,
Myotis lucifugus	ENSMLUG00000017174	2 retrocopies	retro_mluc_115, retro_mluc_252,
Macaca mulatta	ENSMMUG00000000416	2 retrocopies	retro_mmul_2561, retro_mmul_519 ,
Nomascus leucogenys	ENSNLEG00000001204	2 retrocopies	retro_nleu_2182, retro_nleu_717,
Oryctolagus cuniculus	ENSOCUG00000025904	1 retrocopy	retro_ocun_20,
Pan troglodytes	ENSPTRG00000029545	3 retrocopies	retro_ptro_3197, retro_ptro_329, retro_ptro_408,
Rattus norvegicus	ENSRNOG00000025957	1 retrocopy	retro_rnor_2192,
Tursiops truncatus	ENSTTRG00000001487	2 retrocopies	retro_ttru_1376, retro_ttru_1803,