RetrogeneDB ID: retro_ggor_422

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:109369273..109369652(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: OOEP
• Ensembl ID: ENSGGOG00000016832
• Aliases: None
• Description: None

Sequence

>retro_ggor_422
GCTGAGTCAGGGAAATGGACTCCGTCTCACTCCATGGAGAAGCTGCTTAGGTTACCACTTCCCCACCACAGATTCTCATG
GGCTCTGGTGGTTTCTGGTGCAGGAACTGGGAGGCCCTTCTGTGTTCTACCTGGAGGTATGGCTGGCAGATGTGATCTTT
GAGGCAGACCGAGCCGTAATTCCAGGACTGGAGTGGATGAGCCTGTCCCTGTTGATGGTGGACATAGTGGACTCTGGGAT
CCAAGTCAAAATCACAATTTTTGGACAACTCTGTGTATGGAATCGGGTAAAGTGCATGTTCCTGTGCGTGACATGGCTTC
ACCAACAACATCATGCTTAAGCTGAGAAAATAAAACACCTTGAGGAGAATTTGAAGGCC

Alignment

ORF - retro_ggor_422 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 60.47 %
• Parental protein coverage: 85.23 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  SQRGKQTPAHSLEQLRGLPLP-PPQIRIRP-WWFPVQELRDPLVFYLEAWLADELFGPDRGIIPEMEWTS
          ...GK.TP.HS.E.L..LPLP.PPQI.....WWF.VQEL..P.VFYLE.WLAD..F..DR..IP..EW.S
Retrocopy AESGKWTPSHSMEKLLRLPLP<PPQILMGS<WWFLVQELGGPSVFYLEVWLADVIFEADRAVIPGLEWMS

Parental  QALLTVDIVDSGNLVEITVFGRPRVQNRVKSMLLCLAWFHREHRARAEKMKHLEKNLKA
          ..LL.VDIVDSG..V.IT.FG...V.NRVK.M.LC..W.H..H.A.AEK.KHLE.NLKA
Retrocopy LSLLMVDIVDSGIQVKITIFGQLCVWNRVKCMFLCVTWLHQQHHA*AEKIKHLEENLKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.00 RPM
SRP007412_cerebellum	0.00 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.00 RPM	3.11 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_422 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_422 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_432
Pan troglodytes	retro_ptro_329
Macaca mulatta	retro_mmul_519
Callithrix jacchus	retro_cjac_3033

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Parental genes homology:

Parental genes homology involve 11 parental genes, and 22 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000009962	1 retrocopy	retro_cjac_3033,
Homo sapiens	ENSG00000203907	3 retrocopies	retro_hsap_432, retro_hsap_4807, retro_hsap_543,
Gorilla gorilla	ENSGGOG00000016832	3 retrocopies	retro_ggor_2992, retro_ggor_422 , retro_ggor_495,
Loxodonta africana	ENSLAFG00000012754	2 retrocopies	retro_lafr_412, retro_lafr_782,
Myotis lucifugus	ENSMLUG00000017174	2 retrocopies	retro_mluc_115, retro_mluc_252,
Macaca mulatta	ENSMMUG00000000416	2 retrocopies	retro_mmul_2561, retro_mmul_519,
Nomascus leucogenys	ENSNLEG00000001204	2 retrocopies	retro_nleu_2182, retro_nleu_717,
Oryctolagus cuniculus	ENSOCUG00000025904	1 retrocopy	retro_ocun_20,
Pan troglodytes	ENSPTRG00000029545	3 retrocopies	retro_ptro_3197, retro_ptro_329, retro_ptro_408,
Rattus norvegicus	ENSRNOG00000025957	1 retrocopy	retro_rnor_2192,
Tursiops truncatus	ENSTTRG00000001487	2 retrocopies	retro_ttru_1376, retro_ttru_1803,