RetrogeneDB ID: retro_mdom_1012

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 3:210016512..210016879(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: PDCD5
• Ensembl ID: ENSMODG00000012326
• Aliases: None
• Description: programmed cell death 5 [Source:HGNC Symbol;Acc:8764]

Sequence

>retro_mdom_1012
GACAAAGACCTGGAGGCTGCAACAGGGTAGAAGAAGAGGTTGGCTAAATTTCAGGTGAAGTGTGGTCTTGGTGTCCCAGC
ACAGACAAAATGCAGTGAAGCACATATGAGTGACAATATTTTAGCTCAACTTCTGAACCAGTCATAACAAATCAGGTTAA
GTAATACAGCACTTATAAAGTCGAAAAAGGCTAAAACAGTAGAGAACTACCTCATATAGTAGTTGACAAGATATGGATAG
CTGAACAGTAAGGCACTGGAGCAAGAATTAATGGAAATCCTTGAAAAAGTAAGTCAGTAAGTAGGCAAAAAAGAAAATTA
CAAGGAAGTTCAATAGAAGAAAAGTAATGGATTCTGATGAAGATAAT

Alignment

ORF - retro_mdom_1012 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 59.06 %
• Parental protein coverage: 97.6 %
• Number of stop codons detected: 7
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  DEDLEALR--KQRLAELQAKHGDSSGDPAQQEAKHREAEMRNNILAQVLDQSARARLSNLALVKPEKAKA
          D.DLEA....K.RLA..Q.K.G...G.PAQ...K..EA.M..NILAQ.L.QS...RLSN.AL.K..KAK.
Retrocopy DKDLEAATG*KKRLAKFQVKCG--LGVPAQ--TKCSEAHMSDNILAQLLNQS*QIRLSNTALIKSKKAKT

Parental  VENYLIQ-MARYGQLSGKVTEQGLIEI-LEK-VSQQTEKKITVKFNRRKVMDSDEDD
          VENYLI....RYG.L..K..EQ.L.EI.L.K.VS....KKIT.KFNRRKVMDSDED.
Retrocopy VENYLI**LTRYG*LNSKALEQELMEI>LKK*VSK*AKKKITRKFNRRKVMDSDEDN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	89.52 RPM
SRP007412_cerebellum	0.00 RPM	74.11 RPM
SRP007412_heart	0.00 RPM	133.77 RPM
SRP007412_kidney	0.00 RPM	46.09 RPM
SRP007412_liver	0.00 RPM	74.01 RPM
SRP007412_testis	0.00 RPM	132.20 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_1012 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_1012 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 25 parental genes, and 44 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000007555	3 retrocopies	retro_cfam_1659, retro_cfam_535, retro_cfam_838,
Callithrix jacchus	ENSCJAG00000018410	6 retrocopies	retro_cjac_1020, retro_cjac_1959, retro_cjac_2855, retro_cjac_2937, retro_cjac_3841, retro_cjac_3942,
Cavia porcellus	ENSCPOG00000000159	2 retrocopies	retro_cpor_1024, retro_cpor_816,
Dasypus novemcinctus	ENSDNOG00000004010	3 retrocopies	retro_dnov_283, retro_dnov_408, retro_dnov_899,
Equus caballus	ENSECAG00000019406	1 retrocopy	retro_ecab_1007,
Erinaceus europaeus	ENSEEUG00000001182	1 retrocopy	retro_eeur_276,
Homo sapiens	ENSG00000105185	1 retrocopy	retro_hsap_3194,
Gorilla gorilla	ENSGGOG00000006169	1 retrocopy	retro_ggor_1334,
Macropus eugenii	ENSMEUG00000007777	1 retrocopy	retro_meug_1855,
Myotis lucifugus	ENSMLUG00000007141	1 retrocopy	retro_mluc_1497,
Macaca mulatta	ENSMMUG00000015395	1 retrocopy	retro_mmul_2015,
Monodelphis domestica	ENSMODG00000012326	4 retrocopies	retro_mdom_1012 , retro_mdom_1693, retro_mdom_411, retro_mdom_893,
Mus musculus	ENSMUSG00000030417	1 retrocopy	retro_mmus_519,
Oryctolagus cuniculus	ENSOCUG00000013220	1 retrocopy	retro_ocun_828,
Otolemur garnettii	ENSOGAG00000025274	3 retrocopies	retro_ogar_3143, retro_ogar_479, retro_ogar_592,
Ochotona princeps	ENSOPRG00000016642	1 retrocopy	retro_opri_604,
Pongo abelii	ENSPPYG00000009817	1 retrocopy	retro_pabe_2650,
Pan troglodytes	ENSPTRG00000010791	1 retrocopy	retro_ptro_2250,
Rattus norvegicus	ENSRNOG00000013250	1 retrocopy	retro_rnor_167,
Rattus norvegicus	ENSRNOG00000050827	1 retrocopy	retro_rnor_1116,
Sarcophilus harrisii	ENSSHAG00000006705	1 retrocopy	retro_shar_354,
Sus scrofa	ENSSSCG00000002860	2 retrocopies	retro_sscr_1098, retro_sscr_278,
Ictidomys tridecemlineatus	ENSSTOG00000025794	3 retrocopies	retro_itri_1151, retro_itri_1645, retro_itri_563,
Tursiops truncatus	ENSTTRG00000003999	2 retrocopies	retro_ttru_1291, retro_ttru_1472,
Vicugna pacos	ENSVPAG00000012046	1 retrocopy	retro_vpac_383,