RetrogeneDB ID:

retro_hsap_3231

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:5:115106282..115106687(+)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000251118
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:H3F3B
Ensembl ID:ENSG00000132475
Aliases:H3F3B, H3.3B
Description:H3 histone, family 3B (H3.3B) [Source:HGNC Symbol;Acc:4765]


Retrocopy-Parental alignment summary:






>retro_hsap_3231
ATGGCTCTTACAAAGCAGACTGCCTGCAAATCCACCGGTGGTGAAGCACCCAGAAAGCAAGTGGCTACAAAAGCCGCCTG
CAAGAGTGCGCCCACTACTGGAAGGATGAAGAAGCCTCATTGTTACAGGCCGGTTCTGTGGCACTCCGAGAAATTAAACA
TTATCAGAAGTCCACTGAACTTCCGATTCGCAAACTTCCCTTTCAGTATCTGGTGGAGAAATTGCTCAGGACTTTAAAAC
AGATCTGGGCTGCAGAGCGCAGCTACTGGTGCTTTGCAGGAGGCAAGTGAGGCCTATCTGGTTGGCCTTTTTGAAGACAC
CAACCTGTGCGCTATCCATGCCAAACGTGTAACAATTATGCCAAAAGACATCCAGCTAGCACGTTGCATACGTGGAGAAT
GTGCT

ORF - retro_hsap_3231 Open Reading Frame is not conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 83.45 %
Parental protein coverage: 100. %
Number of stop codons detected: 0
Number of frameshifts detected 3


Retrocopy - Parental Gene Alignment:

ParentalMARTKQTARKSTGGKAPRKQLATKAARKSAPSTGGVKKPHRYRP-GTVALREIRRYQKSTELLIRKLPFQ
MA.TKQTA.KSTGG.APRKQ.ATKAA.KSAP.TG..KKPH.YRP.G.VALREI..YQKSTEL.IRKLPFQ
RetrocopyMALTKQTACKSTGGEAPRKQVATKAACKSAPTTGRMKKPHCYRP<GSVALREIKHYQKSTELPIRKLPFQ
ParentalRLVR-EIAQDFKTDLR-FQSAAIGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA
.LV..EIAQDFKTDL...QSAA.GALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLAR.IRGE.A
RetrocopyYLVE<EIAQDFKTDLG<LQSAATGALQEASEAYLVGLFEDTNLCAIHAKRVTIMPKDIQLARCIRGECA

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 0 .00 RPM 358 .42 RPM
bodymap2_adrenal 0 .00 RPM 566 .78 RPM
bodymap2_brain 0 .00 RPM 541 .14 RPM
bodymap2_breast 0 .00 RPM 323 .45 RPM
bodymap2_colon 0 .00 RPM 361 .41 RPM
bodymap2_heart 0 .00 RPM 91 .05 RPM
bodymap2_kidney 0 .00 RPM 326 .19 RPM
bodymap2_liver 0 .00 RPM 114 .76 RPM
bodymap2_lung 0 .00 RPM 619 .46 RPM
bodymap2_lymph_node 0 .00 RPM 265 .57 RPM
bodymap2_ovary 0 .00 RPM 1184 .97 RPM
bodymap2_prostate 0 .00 RPM 568 .46 RPM
bodymap2_skeletal_muscle 0 .00 RPM 113 .47 RPM
bodymap2_testis 0 .06 RPM 496 .18 RPM
bodymap2_thyroid 0 .00 RPM 1081 .08 RPM
bodymap2_white_blood_cells 0 .00 RPM 627 .57 RPM

ChIP-Seq - click to see more details

RNA Polymerase II actvity near the 5' end of retro_hsap_3231 was not detected

EST - click to see more details

No EST(s) were mapped for retro_hsap_3231 retrocopy.

TSS - click to see more details

No TSS is located nearby retro_hsap_3231 retrocopy 5' end.

Lab - click to see more details

retro_hsap_3231 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_3231 has 2 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Pan troglodytes retro_ptro_2183
Gorilla gorilla retro_ggor_2198
Parental genes homology:
Parental genes homology involve 11 parental genes, and 41 retrocopies.

Species Parental gene accession Retrocopies number
Callithrix jacchus ENSCJAG0000001270210 retrocopies
retro_cjac_145, retro_cjac_198, retro_cjac_201, retro_cjac_224, retro_cjac_235, retro_cjac_238, retro_cjac_307, retro_cjac_334, retro_cjac_366, retro_cjac_68,
Dasypus novemcinctus ENSDNOG000000248432 retrocopies
retro_dnov_1624, retro_dnov_775,
Equus caballus ENSECAG000000069041 retrocopy
retro_ecab_916,
Equus caballus ENSECAG000000169481 retrocopy
retro_ecab_266,
Homo sapiens ENSG00000132475 11 retrocopies
retro_hsap_1212, retro_hsap_1552, retro_hsap_2180, retro_hsap_24, retro_hsap_2971, retro_hsap_3231 , retro_hsap_3294, retro_hsap_3299, retro_hsap_389, retro_hsap_4236, retro_hsap_911,
Homo sapiens ENSG000001630415 retrocopies
retro_hsap_2825, retro_hsap_2889, retro_hsap_3102, retro_hsap_3214, retro_hsap_4800,
Latimeria chalumnae ENSLACG000000041181 retrocopy
retro_lcha_104,
Loxodonta africana ENSLAFG000000080833 retrocopies
retro_lafr_837, retro_lafr_959, retro_lafr_99,
Microcebus murinus ENSMICG000000021392 retrocopies
retro_mmur_36, retro_mmur_371,
Mustela putorius furoENSMPUG000000045554 retrocopies
retro_mputfur_389, retro_mputfur_82, retro_mputfur_99, retro_mputfur_990,
Pongo abelii ENSPPYG000000086361 retrocopy
retro_pabe_2662,

Expression level across human populations :
image/svg+xml GBR_HG00142 GBR_HG00099 GBR_HG00114 GBR_HG00143 GBR_HG00131 GBR_HG00137 GBR_HG00133 GBR_HG00119 GBR_HG00111 GBR_HG00134 FIN_HG00378 FIN_HG00338 FIN_HG00349 FIN_HG00375 FIN_HG00315 FIN_HG00277 FIN_HG00328 FIN_HG00321 FIN_HG00377 FIN_HG00183 TSI_NA20756 TSI_NA20538 TSI_NA20798 TSI_NA20532 TSI_NA20765 TSI_NA20518 TSI_NA20513 TSI_NA20512 TSI_NA20771 TSI_NA20786 YRI_NA19114 YRI_NA19099 YRI_NA18870 YRI_NA18907 YRI_NA19223 YRI_NA19214 YRI_NA18916 YRI_NA19093 YRI_NA19118 YRI_NA19213 Toscaniin Italia: Finnish inFinland: British in England and Scotland: Utah Residents (CEPH) with Northernand Western European Ancestry: Yoruba in Ibadan, Nigeria: CEU_NA12760 CEU_NA12827 CEU_NA12872 CEU_NA12751 CEU_NA12873 CEU_NA12400 CEU_NA11930 CEU_NA12004 CEU_NA11831 CEU_NA11843 No expression ( = 0 RPM ) > 0 RPM = 0.04 RPM Legend:


Library Retrogene expression
CEU_NA11831 0 .00 RPM
CEU_NA11843 0 .00 RPM
CEU_NA11930 0 .00 RPM
CEU_NA12004 0 .00 RPM
CEU_NA12400 0 .00 RPM
CEU_NA12751 0 .00 RPM
CEU_NA12760 0 .04 RPM
CEU_NA12827 0 .00 RPM
CEU_NA12872 0 .00 RPM
CEU_NA12873 0 .00 RPM
FIN_HG00183 0 .00 RPM
FIN_HG00277 0 .00 RPM
FIN_HG00315 0 .00 RPM
FIN_HG00321 0 .00 RPM
FIN_HG00328 0 .00 RPM
FIN_HG00338 0 .00 RPM
FIN_HG00349 0 .00 RPM
FIN_HG00375 0 .00 RPM
FIN_HG00377 0 .00 RPM
FIN_HG00378 0 .00 RPM
GBR_HG00099 0 .00 RPM
GBR_HG00111 0 .00 RPM
GBR_HG00114 0 .00 RPM
GBR_HG00119 0 .00 RPM
GBR_HG00131 0 .00 RPM
GBR_HG00133 0 .00 RPM
GBR_HG00134 0 .00 RPM
GBR_HG00137 0 .00 RPM
GBR_HG00142 0 .00 RPM
GBR_HG00143 0 .00 RPM
TSI_NA20512 0 .00 RPM
TSI_NA20513 0 .00 RPM
TSI_NA20518 0 .00 RPM
TSI_NA20532 0 .00 RPM
TSI_NA20538 0 .00 RPM
TSI_NA20756 0 .00 RPM
TSI_NA20765 0 .00 RPM
TSI_NA20771 0 .00 RPM
TSI_NA20786 0 .00 RPM
TSI_NA20798 0 .00 RPM
YRI_NA18870 0 .00 RPM
YRI_NA18907 0 .00 RPM
YRI_NA18916 0 .00 RPM
YRI_NA19093 0 .00 RPM
YRI_NA19099 0 .00 RPM
YRI_NA19114 0 .00 RPM
YRI_NA19118 0 .00 RPM
YRI_NA19213 0 .00 RPM
YRI_NA19214 0 .00 RPM
YRI_NA19223 0 .00 RPM

Indel association:

No indels were associated with its genomic coordinates. Based on Kabza et al. 2015 (PubMed).





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