RetrogeneDB ID:

retro_hsap_1467

Retrocopy
location
Organism:Human (Homo sapiens)
Coordinates:14:106444609..106445233(-)
Located in intron of:None
Retrocopy
information
Ensembl ID:ENSG00000225200
Aliases:None
Status:KNOWN_PSEUDOGENE
Parental gene
information
Parental gene summary:
Parental gene symbol:RPS8
Ensembl ID:ENSG00000142937
Aliases:RPS8, S8
Description:ribosomal protein S8 [Source:HGNC Symbol;Acc:10441]


Retrocopy-Parental alignment summary:






>retro_hsap_1467
ATGGGCACCTCTCGGGACAACTGGCACAAGGGCCGCAAAGCTGGGGGCAAGAGAAGGCCCTGCCACAAGAAGCGGAAGTA
TGAGTTGGGGCGCCCAGCTGCCAACAGCAAGACTGACCCGTGCCGCATCCACACAGTCCGTGTGCGAGGAGGTAACAAGA
AATACTGTGCCCCGAGGCTGGACGTGGGGAATTTCTCCTGGGGCTCAGAATGCTGCGCTGGTGAAACAAGGGTCATCGAT
GTTGTCTACAATGCATCCAATAACGAGCTGGTTCGTACCAAGACCGTGGTGAAGAATTGCATCGTGCCCATCGACAGCAC
GCCCTACCGACAGTGGTACGAGTCCCACTGTGCACTGCCCCTGGGCCGCAAGAAGGGAGCCAAGCTGACTCCTGAGGAAG
AAGAGATTTTAAACAAAAAACGATCTAAAAAAATTCAGAAGAAATATGATGAAAGGAAGAAGAATGCCAAAATGAGCAGT
CTCCTGGGGGAGCAGTTCCAGCAGGGCAAGCTTCTTGCGTGCATGGCTTCAAGGCCGGGACAGTGTGGCCGAGCAGATGG
CTATGTGCTAGAGGGCAAAGAGTTGGAGTTCTATCTTAGGAAAATCAAGGCCCAGAAAGGCAAA

ORF - retro_hsap_1467 Open Reading Frame is conserved.
Retrocopy - Parental Gene Alignment summary:
Percent Identity: 89.42 %
Parental protein coverage: 100. %
Number of stop codons detected: 0
Number of frameshifts detected 0


Retrocopy - Parental Gene Alignment:

ParentalMGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSE
MG.SRDNWHK.RK.GGKR.P.HKKRKYELGRPAAN.K..P.RIHTVRVRGGNKKY.A.RLDVGNFSWGSE
RetrocopyMGTSRDNWHKGRKAGGKRRPCHKKRKYELGRPAANSKTDPCRIHTVRVRGGNKKYCAPRLDVGNFSWGSE
ParentalCCTRKTRIIDVVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKLTPEEEEILNKK
CC...TR.IDVVYNASNNELVRTKT.VKNCIV.IDSTPYRQWYESH.ALPLGRKKGAKLTPEEEEILNKK
RetrocopyCCAGETRVIDVVYNASNNELVRTKTVVKNCIVPIDSTPYRQWYESHCALPLGRKKGAKLTPEEEEILNKK
ParentalRSKKIQKKYDERKKNAKISSLLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARKGK
RSKKIQKKYDERKKNAK.SSLL.EQFQQGKLLAC.ASRPGQCGRADGYVLEGKELEFYLRKIKA.KGK
RetrocopyRSKKIQKKYDERKKNAKMSSLLGEQFQQGKLLACMASRPGQCGRADGYVLEGKELEFYLRKIKAQKGK

Legend:
*Stop codon
>Forward frameshift by one nucleotide
<Reverse frameshift by one nucleotide






RNA-Seq - click to see more details

(Hint: click retrocopy or parental gene accession number on the plot's legend, to show / hide expression level values)

Expression validation based on RNA-Seq data:
Library Retrocopy expression Parental gene expression
bodymap2_adipose 1 .29 RPM 539 .85 RPM
bodymap2_adrenal 1 .82 RPM 743 .31 RPM
bodymap2_brain 0 .63 RPM 176 .67 RPM
bodymap2_breast 1 .50 RPM 378 .82 RPM
bodymap2_colon 2 .26 RPM 728 .15 RPM
bodymap2_heart 0 .07 RPM 195 .24 RPM
bodymap2_kidney 1 .03 RPM 362 .07 RPM
bodymap2_liver 0 .23 RPM 310 .90 RPM
bodymap2_lung 0 .23 RPM 931 .68 RPM
bodymap2_lymph_node 1 .43 RPM 1170 .01 RPM
bodymap2_ovary 3 .78 RPM 1161 .80 RPM
bodymap2_prostate 1 .09 RPM 1422 .79 RPM
bodymap2_skeletal_muscle 0 .67 RPM 536 .16 RPM
bodymap2_testis 1 .09 RPM 415 .20 RPM
bodymap2_thyroid 1 .75 RPM 416 .32 RPM
bodymap2_white_blood_cells 1 .16 RPM 1200 .50 RPM

ChIP-Seq - click to see more details

RNA Polymerase II actvity near the 5' end of retro_hsap_1467 was not detected

EST - click to see more details

No EST(s) were mapped for retro_hsap_1467 retrocopy.

TSS - click to see more details

No TSS is located nearby retro_hsap_1467 retrocopy 5' end.

Lab - click to see more details

retro_hsap_1467 was not experimentally validated.

Retrocopy orthology:
Retrocopy retro_hsap_1467 has 1 orthologous retrocopies within eutheria group .

Species RetrogeneDB ID
Gorilla gorilla retro_ggor_1127
Parental genes homology:
Parental genes homology involve 16 parental genes, and 91 retrocopies.

Species Parental gene accession Retrocopies number
Anolis carolinensis ENSACAG000000156971 retrocopy
retro_acar_124,
Choloepus hoffmanni ENSCHOG0000000878510 retrocopies
retro_chof_1197, retro_chof_1258, retro_chof_1466, retro_chof_1638, retro_chof_2066, retro_chof_2617, retro_chof_2633, retro_chof_274, retro_chof_331, retro_chof_951,
Callithrix jacchus ENSCJAG000000041975 retrocopies
retro_cjac_1068, retro_cjac_181, retro_cjac_3138, retro_cjac_6, retro_cjac_951,
Dipodomys ordii ENSDORG000000092871 retrocopy
retro_dord_429,
Homo sapiens ENSG00000142937 8 retrocopies
retro_hsap_1467 , retro_hsap_1536, retro_hsap_1942, retro_hsap_2034, retro_hsap_2791, retro_hsap_3158, retro_hsap_3410, retro_hsap_635,
Gorilla gorilla ENSGGOG000000056455 retrocopies
retro_ggor_1127, retro_ggor_1170, retro_ggor_1357, retro_ggor_1465, retro_ggor_556,
Myotis lucifugus ENSMLUG0000000155930 retrocopies
retro_mluc_1114, retro_mluc_1132, retro_mluc_1165, retro_mluc_1277, retro_mluc_1288, retro_mluc_1418, retro_mluc_1467, retro_mluc_1476, retro_mluc_1486, retro_mluc_1634, retro_mluc_1656, retro_mluc_1689, retro_mluc_1808, retro_mluc_1911, retro_mluc_1938, retro_mluc_2043, retro_mluc_2055, retro_mluc_2085, retro_mluc_2111, retro_mluc_2153, retro_mluc_2182, retro_mluc_2209, retro_mluc_2414, retro_mluc_460, retro_mluc_662, retro_mluc_730, retro_mluc_773, retro_mluc_820, retro_mluc_821, retro_mluc_906,
Macaca mulatta ENSMMUG000000152702 retrocopies
retro_mmul_275, retro_mmul_70,
Monodelphis domestica ENSMODG000000283891 retrocopy
retro_mdom_998,
Oryctolagus cuniculus ENSOCUG000000124761 retrocopy
retro_ocun_168,
Otolemur garnettii ENSOGAG0000000692216 retrocopies
retro_ogar_1156, retro_ogar_1746, retro_ogar_1895, retro_ogar_2501, retro_ogar_2529, retro_ogar_2556, retro_ogar_2699, retro_ogar_2723, retro_ogar_2947, retro_ogar_308, retro_ogar_3291, retro_ogar_3436, retro_ogar_394, retro_ogar_521, retro_ogar_730, retro_ogar_805,
Pan troglodytes ENSPTRG000000006591 retrocopy
retro_ptro_30,
Rattus norvegicus ENSRNOG000000187682 retrocopies
retro_rnor_222, retro_rnor_235,
Sorex araneus ENSSARG000000008991 retrocopy
retro_sara_462,
Ictidomys tridecemlineatus ENSSTOG000000063223 retrocopies
retro_itri_1337, retro_itri_1380, retro_itri_750,
Tursiops truncatus ENSTTRG000000033884 retrocopies
retro_ttru_1839, retro_ttru_282, retro_ttru_300, retro_ttru_344,

Expression level across human populations :
image/svg+xml GBR_HG00142 GBR_HG00099 GBR_HG00114 GBR_HG00143 GBR_HG00131 GBR_HG00137 GBR_HG00133 GBR_HG00119 GBR_HG00111 GBR_HG00134 FIN_HG00378 FIN_HG00338 FIN_HG00349 FIN_HG00375 FIN_HG00315 FIN_HG00277 FIN_HG00328 FIN_HG00321 FIN_HG00377 FIN_HG00183 TSI_NA20756 TSI_NA20538 TSI_NA20798 TSI_NA20532 TSI_NA20765 TSI_NA20518 TSI_NA20513 TSI_NA20512 TSI_NA20771 TSI_NA20786 YRI_NA19114 YRI_NA19099 YRI_NA18870 YRI_NA18907 YRI_NA19223 YRI_NA19214 YRI_NA18916 YRI_NA19093 YRI_NA19118 YRI_NA19213 Toscaniin Italia: Finnish inFinland: British in England and Scotland: Utah Residents (CEPH) with Northernand Western European Ancestry: Yoruba in Ibadan, Nigeria: CEU_NA12760 CEU_NA12827 CEU_NA12872 CEU_NA12751 CEU_NA12873 CEU_NA12400 CEU_NA11930 CEU_NA12004 CEU_NA11831 CEU_NA11843 No expression ( = 0 RPM ) > 0 RPM = 1.92 RPM Legend:


Library Retrogene expression
CEU_NA11831 1 .20 RPM
CEU_NA11843 1 .51 RPM
CEU_NA11930 1 .92 RPM
CEU_NA12004 1 .06 RPM
CEU_NA12400 1 .26 RPM
CEU_NA12751 0 .73 RPM
CEU_NA12760 1 .62 RPM
CEU_NA12827 1 .32 RPM
CEU_NA12872 0 .90 RPM
CEU_NA12873 1 .31 RPM
FIN_HG00183 1 .15 RPM
FIN_HG00277 1 .81 RPM
FIN_HG00315 0 .55 RPM
FIN_HG00321 0 .51 RPM
FIN_HG00328 0 .85 RPM
FIN_HG00338 1 .19 RPM
FIN_HG00349 1 .56 RPM
FIN_HG00375 0 .86 RPM
FIN_HG00377 0 .93 RPM
FIN_HG00378 0 .98 RPM
GBR_HG00099 0 .67 RPM
GBR_HG00111 1 .23 RPM
GBR_HG00114 1 .24 RPM
GBR_HG00119 0 .81 RPM
GBR_HG00131 0 .52 RPM
GBR_HG00133 0 .89 RPM
GBR_HG00134 0 .68 RPM
GBR_HG00137 0 .96 RPM
GBR_HG00142 0 .61 RPM
GBR_HG00143 1 .44 RPM
TSI_NA20512 0 .93 RPM
TSI_NA20513 0 .60 RPM
TSI_NA20518 1 .22 RPM
TSI_NA20532 1 .60 RPM
TSI_NA20538 0 .97 RPM
TSI_NA20756 0 .99 RPM
TSI_NA20765 0 .68 RPM
TSI_NA20771 1 .11 RPM
TSI_NA20786 0 .73 RPM
TSI_NA20798 0 .69 RPM
YRI_NA18870 1 .46 RPM
YRI_NA18907 0 .42 RPM
YRI_NA18916 0 .88 RPM
YRI_NA19093 0 .81 RPM
YRI_NA19099 0 .75 RPM
YRI_NA19114 0 .92 RPM
YRI_NA19118 1 .49 RPM
YRI_NA19213 0 .69 RPM
YRI_NA19214 0 .37 RPM
YRI_NA19223 0 .92 RPM

Indel association:

No indels were associated with its genomic coordinates. Based on Kabza et al. 2015 (PubMed).





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