RetrogeneDB ID: retro_ggor_447

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 1:149574507..149575073(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: ENSG00000092036
• Ensembl ID: ENSGGOG00000007504
• Aliases: None
• Description: None

Sequence

>retro_ggor_447
AAGGCATGGAAGGAAGTTCGACTGCATAAGACAACATGGTTGAGGTCTGAGATTTTACATGGAGTTATTCAAGAGTTGCT
TGTGGACTACTGTGTGAAGATACAAGACACAAATTTAACTTCTGAGGACAAAAATTTCATGAGACCCTTGAACAGCGGCT
ACTCATAACTGAACTGACATGGCTCTTAGGTCCTAGCCAGGAGAGGGAGATACCTTCACTGCTAGAGCTGGAGAAAGCGG
ACCTTCTGGAATCCATGCCACTCTCAGACGATTTTGTGTGGATGAGGGCTCTGCTACAGCAAGAAGTGGAGGAGTAGCTC
AAGAAGAAATGTTTCACTCTGCTCTGGTACTATGATCCCAATTCAGATGCTGACAGTGAAACCGTGAAGGCAGCAAACGT
GTGGAAACTTGCAGAGGTCCTAGTGGCTAGGAAGCAGCAGTGCCAGTATGCCAAGAGCCAGCAAAAGGAGCAGATGGTGC
TGCTGGAGAAGAAGAGTGCCACCTACTTCCAGCTGCTTCTCCGCTGCCTCATTTTGCTGCAGAGGCTTCTTCAGGAACAA
CGGCTG

Alignment

ORF - retro_ggor_447 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 85.79 %
• Parental protein coverage: 52.07 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  QAWKEVRLHKTTWLRSEILHRVIQELLVDYYVKIQDTNVTSEDK-KFHETLEQRLLVTELMRLLGPSQER
          .AWKEVRLHKTTWLRSEILH.VIQELLVDY.VKIQDTN.TSEDK.KFHETLEQRLL.TEL..LLGPSQER
Retrocopy KAWKEVRLHKTTWLRSEILHGVIQELLVDYCVKIQDTNLTSEDK<KFHETLEQRLLITELTWLLGPSQER

Parental  EIPPLLGLEKADLLELMPLSEDFVWMTARLQQEVEEQLKKKCFTLLCYYDPSSDADSETVKAAKVWKLAE
          EIP.LL.LEKADLLE.MPLS.DFVWM.A.LQQEVEE.LKKKCFTLL.YYDP.SDADSETVKAA.VWKLAE
Retrocopy EIPSLLELEKADLLESMPLSDDFVWMRALLQQEVEE*LKKKCFTLLWYYDPNSDADSETVKAANVWKLAE

Parental  VLVGEQQQCQDAKSQQKEQMLLLEKKSATYSQVLLRCLTLLQRLLQEHRL
          VLV...QQCQ.AKSQQKEQM.LLEKKSATY.Q.LLRCL.LLQRLLQE.RL
Retrocopy VLVARKQQCQYAKSQQKEQMVLLEKKSATYFQLLLRCLILLQRLLQEQRL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	16.98 RPM
SRP007412_cerebellum	0.00 RPM	19.58 RPM
SRP007412_heart	0.00 RPM	7.47 RPM
SRP007412_kidney	0.00 RPM	43.26 RPM
SRP007412_liver	0.00 RPM	40.46 RPM
SRP007412_testis	0.00 RPM	25.17 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_447 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_447 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_469
Pan troglodytes	retro_ptro_352
Pongo abelii	retro_pabe_265

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Parental genes homology:

Parental genes homology involve 8 parental genes, and 8 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000008389	1 retrocopy	retro_cjac_757,
Dasypus novemcinctus	ENSDNOG00000002575	1 retrocopy	retro_dnov_712,
Homo sapiens	ENSG00000092036	1 retrocopy	retro_hsap_469,
Gorilla gorilla	ENSGGOG00000007504	1 retrocopy	retro_ggor_447 ,
Myotis lucifugus	ENSMLUG00000012934	1 retrocopy	retro_mluc_1946,
Otolemur garnettii	ENSOGAG00000000586	1 retrocopy	retro_ogar_382,
Pongo abelii	ENSPPYG00000005651	1 retrocopy	retro_pabe_265,
Pan troglodytes	ENSPTRG00000006153	1 retrocopy	retro_ptro_352,