RetrogeneDB ID: retro_ggor_2358

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 6:77393995..77394416(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: RPS6
• Ensembl ID: ENSGGOG00000002652
• Aliases: None
• Description: 40S ribosomal protein S6 [Source:UniProtKB/TrEMBL;Acc:G3QJL6]

Sequence

>retro_ggor_2358
ATTGACTATGAACATAAACTTCATGGGTTTTCTTAGAAGCATATGGCCGCAGACGTTGCTGCTGATGCTCTGGGTGAAGA
ATGAAAGGGTTATGTTGTCCACATCAGTGGTGGGAACCACAAATAAGATTTCCCCTTGAAGCAGGGTATCTTGACCCAAG
GCTGTACCTGCCTGTGACTAAGGGGTATTCCTGTTTTAGACCAAAGAGAACTGAAGAAAGAAAATGCAAATCTGTTTAGG
GTTGCATTATGGATGCCAATCTGAGCATTCTTAACACCGTTTTTGTAAAAGAGAGAGAGAGAGAGAAGGATATTCCTGGA
CTGACTGATACTATAGTGCCTCATTGCCTGAGGCCCAAAGAGCTAGCAGAGTCTGCAAACTTTTCAATCTGTCTGAAAAA
GATGATGTCTGCCAATATGTT

Alignment

ORF - retro_ggor_2358 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 61.81 %
• Parental protein coverage: 56.22 %
• Number of stop codons detected: 4
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  VDDERKLRTFYEKRMATEVAADALGEEWKGYVVRISGGNDKQGFP-MKQGVLTHGRVRLLLSKGHSCYRP
          .D.E.KL..F..K.MA..VAADALGEE.KGYVV.ISGGN.K..FP....G.L...R..L...KG.SC.RP
Retrocopy IDYEHKLHGFS*KHMAADVAADALGEE*KGYVVHISGGNHK*DFP<LEAGYLDP-RLYLPVTKGYSCFRP

Parental  RRTGERKRKSVRGCIVDANLSVLNLVIV--KKGEKDIPGLTDTTVPRRLGPK-RASRIRKLFNLSKEDDV
          .RT.ERK.KSV.GCI.DANLS.LN.V.V.......DIPGLTDT.VP..L.PK.RASR..KLFNLS..DDV
Retrocopy KRTEERKCKSV*GCIMDANLSILNTVFVXXXXXXXDIPGLTDTIVPHCLRPK<RASRVCKLFNLSEKDDV

Parental  RQYV
          .QYV
Retrocopy CQYV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	237.47 RPM
SRP007412_cerebellum	0.00 RPM	296.35 RPM
SRP007412_heart	0.00 RPM	178.61 RPM
SRP007412_kidney	0.00 RPM	713.22 RPM
SRP007412_liver	0.00 RPM	518.06 RPM
SRP007412_testis	0.00 RPM	466.61 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_2358 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_2358 has 1 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pongo abelii	retro_pabe_2882

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Parental genes homology:

Parental genes homology involve 17 parental genes, and 101 retrocopies.

Species	Parental gene accession	Retrocopies number
Anolis carolinensis	ENSACAG00000017634	1 retrocopy	retro_acar_20,
Ailuropoda melanoleuca	ENSAMEG00000002925	14 retrocopies	retro_amel_1040, retro_amel_1250, retro_amel_1384, retro_amel_1526, retro_amel_1646, retro_amel_1676, retro_amel_189, retro_amel_312, retro_amel_334, retro_amel_382, retro_amel_510, retro_amel_568, retro_amel_657, retro_amel_841,
Canis familiaris	ENSCAFG00000001615	4 retrocopies	retro_cfam_184, retro_cfam_1936, retro_cfam_48, retro_cfam_87,
Callithrix jacchus	ENSCJAG00000020612	6 retrocopies	retro_cjac_1246, retro_cjac_18, retro_cjac_180, retro_cjac_190, retro_cjac_2982, retro_cjac_59,
Cavia porcellus	ENSCPOG00000003750	4 retrocopies	retro_cpor_1244, retro_cpor_22, retro_cpor_317, retro_cpor_486,
Dasypus novemcinctus	ENSDNOG00000007241	1 retrocopy	retro_dnov_1192,
Equus caballus	ENSECAG00000016190	5 retrocopies	retro_ecab_175, retro_ecab_312, retro_ecab_603, retro_ecab_771, retro_ecab_861,
Ficedula albicollis	ENSFALG00000003078	1 retrocopy	retro_falb_24,
Felis catus	ENSFCAG00000002541	26 retrocopies	retro_fcat_1082, retro_fcat_1108, retro_fcat_1154, retro_fcat_1262, retro_fcat_1373, retro_fcat_1642, retro_fcat_1679, retro_fcat_1760, retro_fcat_1791, retro_fcat_1934, retro_fcat_1937, retro_fcat_1963, retro_fcat_198, retro_fcat_238, retro_fcat_328, retro_fcat_358, retro_fcat_380, retro_fcat_392, retro_fcat_493, retro_fcat_659, retro_fcat_738, retro_fcat_750, retro_fcat_850, retro_fcat_894, retro_fcat_912, retro_fcat_968,
Gorilla gorilla	ENSGGOG00000002652	13 retrocopies	retro_ggor_1430, retro_ggor_1703, retro_ggor_2097, retro_ggor_2358 , retro_ggor_2439, retro_ggor_2769, retro_ggor_2863, retro_ggor_2864, retro_ggor_616, retro_ggor_670, retro_ggor_777, retro_ggor_896, retro_ggor_965,
Loxodonta africana	ENSLAFG00000010766	4 retrocopies	retro_lafr_1021, retro_lafr_1239, retro_lafr_59, retro_lafr_667,
Macaca mulatta	ENSMMUG00000003412	1 retrocopy	retro_mmul_263,
Monodelphis domestica	ENSMODG00000004095	1 retrocopy	retro_mdom_301,
Ochotona princeps	ENSOPRG00000012290	5 retrocopies	retro_opri_123, retro_opri_642, retro_opri_78, retro_opri_862, retro_opri_895,
Rattus norvegicus	ENSRNOG00000049025	8 retrocopies	retro_rnor_1008, retro_rnor_1189, retro_rnor_1988, retro_rnor_1990, retro_rnor_2085, retro_rnor_2635, retro_rnor_479, retro_rnor_718,
Sarcophilus harrisii	ENSSHAG00000005486	1 retrocopy	retro_shar_549,
Sus scrofa	ENSSSCG00000005169	6 retrocopies	retro_sscr_187, retro_sscr_425, retro_sscr_645, retro_sscr_856, retro_sscr_940, retro_sscr_983,