RetrogeneDB ID: retro_ggor_1633

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 2a:38483928..38484486(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSGGOG00000024969
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: STRAP
• Ensembl ID: ENSGGOG00000009939
• Aliases: None
• Description: None

Sequence

>retro_ggor_1633
AAAACTTCTCGACTTTGGGATCATGCTGCTATGACAGAAGTGAAATCTCTAAATTTTAATATGTCTGTTAGTAGTACAAA
ATACACTCCTGAGGGAGAGATTTTGGTTATAACTTATGGACGATCTATTGCTTTTCATAGTGCAGTAAGTTTGAACCCAG
TTACATCCTTTGAAGCTCCTGCAACCATCAATTCTGCATCTCTTCATCCTGAGAAAGAATTTCTTGTTGCAGGTGGTGAA
GATTTTAAACTTTGTAAGTATTTTAACCGTGGAGAAGAATTCGAATCCTACAAGGGATACTTTGGTCCTATTCACTGTGT
GAGATTTAGTCGTGATGGAGAACTCTGTGCCAGTGGTTCTGAAGATGGAACATTGAGACTAGGACAAACTGTGGTAGGAA
AAACATACGGCCTTTGGAAATGTGTGCTTCCTGAAGAAGAGAGTGGTGAGCTGGCAAAGCCAAAGATTGGCTTTCCAGAG
ACAACAGAAGAGGAGCTAGAAGAAATTGTTTCAGAGAATTCAGATTGCATCTATTCTTCAACTCCTGATGTTAAGGCC

Alignment

ORF - retro_ggor_1633 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 88.24 %
• Parental protein coverage: 53.74 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KICRLWDHATMTEVKSLNFNMSVSSMEYIPEGEILVITYGRSIAFHSAVSLDPIKSFEAPATINSASLHP
          K..RLWDHA.MTEVKSLNFNMSVSS..Y.PEGEILVITYGRSIAFHSAVSL.P..SFEAPATINSASLHP
Retrocopy KTSRLWDHAAMTEVKSLNFNMSVSSTKYTPEGEILVITYGRSIAFHSAVSLNPVTSFEAPATINSASLHP

Parental  EKEFLVAGGEDFKLYKYDYNSGEELESYKGHFGPIHCVRFSPDGELYASGSEDGTLRLWQTVVGKTYGLW
          EKEFLVAGGEDFKL.KY..N.GEE.ESYKG.FGPIHCVRFS.DGEL.ASGSEDGTLRL.QTVVGKTYGLW
Retrocopy EKEFLVAGGEDFKLCKY-FNRGEEFESYKGYFGPIHCVRFSRDGELCASGSEDGTLRLGQTVVGKTYGLW

Parental  KCVLPEEDSGELAKPKIGFPETTEEELEEIASENSDCIYPSAPDVKA
          KCVLPEE.SGELAKPKIGFPETTEEELEEI.SENSDCIY.S.PDVKA
Retrocopy KCVLPEEESGELAKPKIGFPETTEEELEEIVSENSDCIYSSTPDVKA

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	1.44 RPM	41.48 RPM
SRP007412_cerebellum	1.10 RPM	23.64 RPM
SRP007412_heart	0.28 RPM	9.16 RPM
SRP007412_kidney	1.27 RPM	28.17 RPM
SRP007412_liver	0.84 RPM	14.30 RPM
SRP007412_testis	2.07 RPM	45.27 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1633 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1633 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2092
Pan troglodytes	retro_ptro_1538
Pongo abelii	retro_pabe_2005

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Parental genes homology:

Parental genes homology involve 12 parental genes, and 24 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000007422	2 retrocopies	retro_chof_1098, retro_chof_1620,
Callithrix jacchus	ENSCJAG00000021593	1 retrocopy	retro_cjac_2503,
Homo sapiens	ENSG00000023734	2 retrocopies	retro_hsap_2092, retro_hsap_3723,
Gorilla gorilla	ENSGGOG00000001579	3 retrocopies	retro_ggor_2540, retro_ggor_2615, retro_ggor_2623,
Gorilla gorilla	ENSGGOG00000009939	1 retrocopy	retro_ggor_1633 ,
Macaca mulatta	ENSMMUG00000013307	2 retrocopies	retro_mmul_1695, retro_mmul_985,
Mus musculus	ENSMUSG00000030224	1 retrocopy	retro_mmus_794,
Nomascus leucogenys	ENSNLEG00000004160	2 retrocopies	retro_nleu_1301, retro_nleu_1970,
Ochotona princeps	ENSOPRG00000015211	3 retrocopies	retro_opri_1029, retro_opri_217, retro_opri_541,
Pongo abelii	ENSPPYG00000004334	3 retrocopies	retro_pabe_2005, retro_pabe_3134, retro_pabe_3212,
Pan troglodytes	ENSPTRG00000004734	2 retrocopies	retro_ptro_1538, retro_ptro_2616,
Tursiops truncatus	ENSTTRG00000003466	2 retrocopies	retro_ttru_581, retro_ttru_974,