RetrogeneDB ID: retro_ggor_1026

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: 14:12157616..12157969(+)
• Located in intron of: ENSGGOG00000006096

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: IFT20
• Ensembl ID: ENSGGOG00000004568
• Aliases: None
• Description: None

Sequence

>retro_ggor_1026
ATGACACACCTCCTCCTGACTGTCACTGTCACTCCTTCAGAGCAGAGCTTCTCTAGGGAACTTGGATGGGAAACAACTAT
GGTAAAGGACATCCTGGGTGAAGAGGGACTGCACTTTGATGAGTTGAACAAGCTGTGGGTGTTGGACTCAGAGGTTACCC
AGCAGACCACAGAGCTCAAAGAAGAGTGCAAGAACTTTGTGGACAAAACTGGCCAGTTTCAGAAAACAGTTGGTGGTTTA
ACTGAGCTTGTTGATAAACTTGCAAAAAAAGCGTAAAATGAGAAGATGAAGGCCATGGTGCTCAGAACTTGCTCAAATCA
ATAGCAAAGCAGAGAGAAGCTCAACAACTTCAG

Alignment

ORF - retro_ggor_1026 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 82.35 %
• Parental protein coverage: 74.68 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MTHLLLTATVTPSEQNSSREPGWETAMAKDILGEAGLHFDELNKLRVLDPEVTQQTIELKEECKDFVDKI
          MTHLLLT.TVTPSEQ..SRE.GWET.M.KDILGE.GLHFDELNKL.VLD.EVTQQT.ELKEECK.FVDK.
Retrocopy MTHLLLTVTVTPSEQSFSRELGWETTMVKDILGEEGLHFDELNKLWVLDSEVTQQTTELKEECKNFVDKT

Parental  GQFQKIVGGLIELVDQLAKEAENEKMKAI-GARNLLKSIAKQREAQQQQ
          GQFQK.VGGL.ELVD.LAK.A.NEKMKA..GA.NLLKSIAKQREAQQ.Q
Retrocopy GQFQKTVGGLTELVDKLAKKA*NEKMKAM<GAQNLLKSIAKQREAQQLQ

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.14 RPM	13.04 RPM
SRP007412_cerebellum	0.12 RPM	20.05 RPM
SRP007412_heart	0.06 RPM	3.85 RPM
SRP007412_kidney	0.04 RPM	20.32 RPM
SRP007412_liver	0.13 RPM	16.93 RPM
SRP007412_testis	0.10 RPM	69.83 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_1026 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_1026 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1314
Pongo abelii	retro_pabe_1097
Macaca mulatta	retro_mmul_2165
Callithrix jacchus	retro_cjac_687

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Parental genes homology:

Parental genes homology involve 21 parental genes, and 36 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005111	2 retrocopies	retro_amel_1011, retro_amel_1337,
Bos taurus	ENSBTAG00000008110	1 retrocopy	retro_btau_257,
Callithrix jacchus	ENSCJAG00000012534	2 retrocopies	retro_cjac_2404, retro_cjac_687,
Cavia porcellus	ENSCPOG00000003153	1 retrocopy	retro_cpor_152,
Echinops telfairi	ENSETEG00000018843	2 retrocopies	retro_etel_1045, retro_etel_1181,
Homo sapiens	ENSG00000109083	1 retrocopy	retro_hsap_1314,
Gorilla gorilla	ENSGGOG00000004568	2 retrocopies	retro_ggor_1026 , retro_ggor_1217,
Microcebus murinus	ENSMICG00000005074	1 retrocopy	retro_mmur_987,
Myotis lucifugus	ENSMLUG00000008709	2 retrocopies	retro_mluc_180, retro_mluc_1924,
Macaca mulatta	ENSMMUG00000019143	2 retrocopies	retro_mmul_2165, retro_mmul_2234,
Monodelphis domestica	ENSMODG00000019233	1 retrocopy	retro_mdom_681,
Mustela putorius furo	ENSMPUG00000014353	1 retrocopy	retro_mputfur_247,
Mus musculus	ENSMUSG00000001105	1 retrocopy	retro_mmus_3245,
Nomascus leucogenys	ENSNLEG00000001883	2 retrocopies	retro_nleu_1067, retro_nleu_1941,
Oryctolagus cuniculus	ENSOCUG00000007773	1 retrocopy	retro_ocun_438,
Otolemur garnettii	ENSOGAG00000003333	2 retrocopies	retro_ogar_1169, retro_ogar_72,
Ochotona princeps	ENSOPRG00000005826	6 retrocopies	retro_opri_110, retro_opri_1185, retro_opri_205, retro_opri_293, retro_opri_375, retro_opri_872,
Pongo abelii	ENSPPYG00000008087	2 retrocopies	retro_pabe_1097, retro_pabe_1322,
Sus scrofa	ENSSSCG00000023719	1 retrocopy	retro_sscr_315,
Ictidomys tridecemlineatus	ENSSTOG00000007554	1 retrocopy	retro_itri_713,
Tupaia belangeri	ENSTBEG00000005557	2 retrocopies	retro_tbel_180, retro_tbel_1954,