RetrogeneDB ID: retro_fcat_581

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: B1:153893351..153893791(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSFCAG00000028002
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: PIN4
• Ensembl ID: ENSFCAG00000012036
• Aliases: None
• Description: protein (peptidylprolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin) [Source:HGNC Symbol;Acc:8992]

Sequence

>retro_fcat_581
GAGGCAACTGAAGCCTTTGACAGTACAGCTGCAAGATTCGAAGATGCCACCCAAGGGAAAAAGCAGTTCCAGGAAAGGGA
GGGGGGGAAGGAGGAGCAGCCTCTGGGAGTGACAGTTCTGACAAGAAGGCTCAGGGTCCCAAAGGTGGTGGCAATGCAAT
AAAGGTCAGACACATTCTGTGTGAAAAACATGGGAAAATCATGCAAGCCATGGAAAAGTTGAAGTCTGGAATGAGATTCA
ATGAAGTGGCCACACAGTATAGTAGAGATAAAGCCAGGCAAGGGGGTGACTTGGGTTGGATGACCAGAGGTACCAAGGTG
GGACCATTTCAAGAAGCAGCATTTGCCTAGCCCATAAGTGGGCTGGATAAACCTGTGTTTACAGACCCTCCAGTTAAGAC
AAAATTTGGATATCATATTATTATGGTTAAAGGGAGAAAA

Alignment

ORF - retro_fcat_581 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.22 %
• Parental protein coverage: 96.67 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  QATEAFDSTA-QDSKMPPKGKSRS-GKGG-KGGAASGSDSSDKKAQGPKGGGNAVKVRHILCEKHGKIME
          .ATEAFDSTA.QDSKMPPKGKS.S.GKGG..GGAASGSDSSDKKAQGPKGGGNA.KVRHILCEKHGKIM.
Retrocopy EATEAFDSTA>QDSKMPPKGKSSS>GKGGGEGGAASGSDSSDKKAQGPKGGGNAIKVRHILCEKHGKIMQ

Parental  AMEKLKSGMRFNEVAIQYSEDKARQGGDLGWMTRGTMVGPFQEAAFALPISGLDKPVFTDPPVKTKFGYH
          AMEKLKSGMRFNEVA.QYS.DKARQGGDLGWMTRGT.VGPFQEAAFA.PISGLDKPVFTDPPVKTKFGYH
Retrocopy AMEKLKSGMRFNEVATQYSRDKARQGGDLGWMTRGTKVGPFQEAAFA*PISGLDKPVFTDPPVKTKFGYH

Parental  IIMVEGRK
          IIMV.GRK
Retrocopy IIMVKGRK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.11 RPM	5.62 RPM
SRP017611_kidney	0.00 RPM	12.47 RPM
SRP017611_liver	0.00 RPM	5.05 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_581 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_581 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 59 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000005801	1 retrocopy	retro_amel_1553,
Canis familiaris	ENSCAFG00000032230	1 retrocopy	retro_cfam_212,
Callithrix jacchus	ENSCJAG00000004992	10 retrocopies	retro_cjac_1218, retro_cjac_1587, retro_cjac_1631, retro_cjac_1720, retro_cjac_1729, retro_cjac_1746, retro_cjac_1863, retro_cjac_2670, retro_cjac_2704, retro_cjac_2829,
Cavia porcellus	ENSCPOG00000011401	1 retrocopy	retro_cpor_631,
Dipodomys ordii	ENSDORG00000006985	2 retrocopies	retro_dord_109, retro_dord_352,
Felis catus	ENSFCAG00000012036	5 retrocopies	retro_fcat_1325, retro_fcat_1411, retro_fcat_581 , retro_fcat_723, retro_fcat_769,
Homo sapiens	ENSG00000102309	3 retrocopies	retro_hsap_1562, retro_hsap_1604, retro_hsap_304,
Gorilla gorilla	ENSGGOG00000016008	4 retrocopies	retro_ggor_1187, retro_ggor_1210, retro_ggor_328, retro_ggor_338,
Loxodonta africana	ENSLAFG00000018261	1 retrocopy	retro_lafr_212,
Macropus eugenii	ENSMEUG00000003611	1 retrocopy	retro_meug_368,
Microcebus murinus	ENSMICG00000001640	4 retrocopies	retro_mmur_138, retro_mmur_294, retro_mmur_483, retro_mmur_674,
Myotis lucifugus	ENSMLUG00000012073	2 retrocopies	retro_mluc_2189, retro_mluc_923,
Mustela putorius furo	ENSMPUG00000005287	3 retrocopies	retro_mputfur_1285, retro_mputfur_417, retro_mputfur_858,
Mus musculus	ENSMUSG00000079480	8 retrocopies	retro_mmus_1656, retro_mmus_1703, retro_mmus_2205, retro_mmus_2741, retro_mmus_2921, retro_mmus_3673, retro_mmus_399, retro_mmus_821,
Nomascus leucogenys	ENSNLEG00000018119	1 retrocopy	retro_nleu_2957,
Oryctolagus cuniculus	ENSOCUG00000008715	2 retrocopies	retro_ocun_137, retro_ocun_835,
Pongo abelii	ENSPPYG00000020460	2 retrocopies	retro_pabe_146, retro_pabe_384,
Rattus norvegicus	ENSRNOG00000050051	6 retrocopies	retro_rnor_1755, retro_rnor_2368, retro_rnor_2575, retro_rnor_2576, retro_rnor_480, retro_rnor_553,
Sorex araneus	ENSSARG00000003732	2 retrocopies	retro_sara_201, retro_sara_248,