RetrogeneDB ID: retro_fcat_1338

Retrocopy location

• Organism: Cat (Felis catus)
• Coordinates: C2:45792380..45793517(-)
• Located in intron of: ENSFCAG00000007322

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CDC37
• Ensembl ID: ENSFCAG00000009437
• Aliases: None
• Description: cell division cycle 37 [Source:HGNC Symbol;Acc:1735]

Sequence

>retro_fcat_1338
ATGGTGGACTATAGCGTGTGGGACCACATCGAGGTGTCTGACGATGAGGACGAGACGCACCCCAAAATCGATACAGCCAG
TCTCTTCTGCTGGCGGCACCAGGCCCGGGTGGAGCGCATGGAGCAGTTCCAGAAGGAGGAGAAGGAGCTGGAGAGGGGCT
GCCGCCAGTGCAGGCGCAAGGTGGCCGAGTGCCAGTGGAGGCTGAAGAAGCTGGAGGCCGCGGAGGGCGAGGGCAGCAAG
GCAGAGCTAGAGTGGCTGCAGGCTGAGGCTCAGCAGCTGCGCAAGGAGGAGCGGAGCTGGGAGCAGAAGCTGGAGGAGAT
GCGCAAGAAGGAGAAGAGCATGCCCTGGAACGTGGACACACTCAGCAAGGACGGCTTCAGCAAGAGCATGGTCAATACCA
AGCCAAAGCAGACGGAGGAGTCGTCAGAGGAAGTGAGGGAGCAGAAACACAAAACGTTCGTGGAGAAGTATGAGAAACAG
ATCAAGCACTTTGGCATGCTCCATCACTGGGACGACAGCCAGAAGTACCTGTCGGACAATGTCCATCTGGTGTGCGAGGA
AACCACCAACTACCTTGTCATCTGGTGCACTGACCTAGAGGTGGAGGAGAAATGTGCACTCATGGAGCAGGTGGCCCACC
AGACCATCGTCATGCAGTTCATCCTGGAGCTGGCTAAGAGCCTGAAGGTGGATCCCTGTGCCTGCTTCCGGCAGTTCTTC
ACCAAGATCAGGACAGCCGACTGCCAGTACATGGAGGGCTTCAACGACGAACTGGAGGCCTTCAAGGAGCGCGTGCGGCG
CCACGCCAAGCTGCGCATGGAGAAGGCCATGAAGGAATAGGAGGAGCAGCAGCTCCGGAAGTGGCTCGGCCCGGGCGGTT
TGGACCCCGTGGAGGTCTACCAGTCTCTCTCTGAGGAACTACAGAAATGCTTCAACATGAAAGATGTGCAGATGCTTCAA
GACGCCATCAGCAAGATGGACCGCACCGATGCTAAGTACCACATGCAGCCCTGCATCGACTCTGGCCTCTGGGTCCCCAA
CTCCAAGTCCAGCGAGGCCAAGGAGAGGGAGGAGACAGGCCCTGGGGACCCCTTGCTGGAAGCTGGCCCCAAGCCAGGAG
ACAAGAAGGATGTCAGT

Alignment

ORF - retro_fcat_1338 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 91.03 %
• Parental protein coverage: 99.74 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MVDYSVWDHIEVSDDEDETHPNIDTASLFRWRHQARVERMEQFQKEKEELERGCRECRRKVAECQRRLKE
          MVDYSVWDHIEVSDDEDETHP.IDTASLF.WRHQARVERMEQFQKE..ELERGCR.CRRKVAECQ.RLK.
Retrocopy MVDYSVWDHIEVSDDEDETHPKIDTASLFCWRHQARVERMEQFQKEEKELERGCRQCRRKVAECQWRLKK

Parental  LEAAEGEGSKAELERLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPEQAEE
          LEAAEGEGSKAELE.LQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKP.Q.EE
Retrocopy LEAAEGEGSKAELEWLQAEAQQLRKEERSWEQKLEEMRKKEKSMPWNVDTLSKDGFSKSMVNTKPKQTEE

Parental  ESEEVREQKHKTFVEKYEKQIKHFGMLRRWDDSQKYLSDNVHLVCEETANYLVIWCIDLEVEEKCALMEQ
          .SEEVREQKHKTFVEKYEKQIKHFGML..WDDSQKYLSDNVHLVCEET.NYLVIWC.DLEVEEKCALMEQ
Retrocopy SSEEVREQKHKTFVEKYEKQIKHFGMLHHWDDSQKYLSDNVHLVCEETTNYLVIWCTDLEVEEKCALMEQ

Parental  VAHQTIVMQFILELAKSLKVDPRACFRQFFTKIKTADRQYMEGFNDELEAFKERVRGRAKLRIEKAMKEY
          VAHQTIVMQFILELAKSLKVDP.ACFRQFFTKI.TAD.QYMEGFNDELEAFKERVR..AKLR.EKAMKE.
Retrocopy VAHQTIVMQFILELAKSLKVDPCACFRQFFTKIRTADCQYMEGFNDELEAFKERVRRHAKLRMEKAMKE*

Parental  EEEERRKRLGPGGLDPVEVYESLPEELQKCFDVKDVQMLQDAISKMDPTDAKYHMQRCIDSGLWVPNSKS
          EE...RK.LGPGGLDPVEVY.SL.EELQKCF..KDVQMLQDAISKMD.TDAKYHMQ.CIDSGLWVPNSKS
Retrocopy EEQQLRKWLGPGGLDPVEVYQSLSEELQKCFNMKDVQMLQDAISKMDRTDAKYHMQPCIDSGLWVPNSKS

Parental  SEAKEGEEAGPGDPLLEAGPKPGDKKDVS
          SEAKE.EE.GPGDPLLEAGPKPGDKKDVS
Retrocopy SEAKEREETGPGDPLLEAGPKPGDKKDVS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP017611_brain	0.57 RPM	41.89 RPM
SRP017611_kidney	0.72 RPM	36.17 RPM
SRP017611_liver	0.10 RPM	15.87 RPM

ChIP-Seq

Felis catus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_fcat_1338 retrocopy.

TSS

Felis catus was not studied using FANTOM5 data.

Lab

retro_fcat_1338 was not experimentally validated.

Homology

Retrocopy orthology:

Felis catus does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 5 parental genes, and 5 retrocopies.

Species	Parental gene accession	Retrocopies number
Felis catus	ENSFCAG00000009437	1 retrocopy	retro_fcat_1338 ,
Gorilla gorilla	ENSGGOG00000008098	1 retrocopy	retro_ggor_2299,
Macropus eugenii	ENSMEUG00000002278	1 retrocopy	retro_meug_1373,
Pongo abelii	ENSPPYG00000009551	1 retrocopy	retro_pabe_2790,
Tursiops truncatus	ENSTTRG00000009560	1 retrocopy	retro_ttru_1073,