RetrogeneDB ID: retro_chof_867

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_158281:1234..2078(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: MAK16
• Ensembl ID: ENSCHOG00000009081
• Aliases: None
• Description: MAK16 homolog (S. cerevisiae) [Source:HGNC Symbol;Acc:13703]

Sequence

>retro_chof_867
ATGCAGTCAGATGACGTTATCTGGGATACACTAGGAAACAAACGATTTTGTTCCTTCAAAATAAGAACCAAGACTCAGAG
CTTTTGCAGAAATGAATACAGCCTAACTGGATTATGCAATCGATTGTCCTGTCCCCTGGCAGAAAGTCAGTATGCCACCA
TCAAAGAAGAAAAAGGACTGTGCTACTTATATATGAAGGTTATAGAACGAGCAGCTTTTCCTAGGCGTCTCTGGGAACGG
GTCCAGCTCGGTAAAAACTGTGAGAAAGCACTGGAGCAAACAGATGAAAATCTAATTTACTGGCCCCGTTTTATTTGACA
TAAATGTAAACAGAGATTCACCAAGATTACCCAGTACCTGATTCGAATTCGAAAACTTACACTAAAGGGACAGAGGAAAA
TTGTTCCTTTGAGTAAGAAGGTAGAACAGAGGGAAAAAAGGAGAGAGGAAAAGGCATTGATAGCTGCTCAGCTGGATAAC
GCCATTGAAAAGGAATTACTGGAAAGACTGAAACAAGATACGTATAGCGACATCTACAACTTCCCCATTCGTGCCTTCGA
CAAGGCCCTGGAACAGCAGGAGGCAGAGAGTGACTCTTCAGATGCTGAGGAAAAAGATGATGAAGAAGAAGAAGAAGAAG
ATTTGGGAACGAGAGAATTTGCGGAAGATGATGAGGTGGATGAGAGTGACATAAGTGACTTTGATAAACTGGACATCAGC
AGTAAGCGGTAATGAAGATCAGGATCAGAGATCATCCAGTGAGGACGAAGAAAAGTCCCTGGATGCCAGACACAAAGGCA
AAACACCTTTGAAAGGACCTTTGCGGAGAAAACGAGCCTATGTA

Alignment

ORF - retro_chof_867 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.01 %
• Parental protein coverage: 94.26 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  MQSDDXXXXXXXXXXXXXXXXXTKTQSFCRNEYSLTGLCNRSSCPLANSQYATIKEEKGQCYLYMKVIER
          MQSDD.................TKTQSFCRNEYSLTGLCNR.SCPLA.SQYATIKEEKG.CYLYMKVIER
Retrocopy MQSDDVIWDTLGNKRFCSFKIRTKTQSFCRNEYSLTGLCNRLSCPLAESQYATIKEEKGLCYLYMKVIER

Parental  AAFPRRLWERVLLSKNYEKALEQIDENLIYWPRFIRHKCKQRFTKITQYLIRIRKLTLKRQRKIVPLSKK
          AAFPRRLWERV.L.KN.EKALEQ.DENLIYWPRFI.HKCKQRFTKITQYLIRIRKLTLK.QRKIVPLSKK
Retrocopy AAFPRRLWERVQLGKNCEKALEQTDENLIYWPRFI*HKCKQRFTKITQYLIRIRKLTLKGQRKIVPLSKK

Parental  VERREKRREEKALIAAQLDNAIEKELLERLKQDTYSDIYNFPIHAFDKALEQQ--EAESDSSDAEEKDDE
          VE.REKRREEKALIAAQLDNAIEKELLERLKQDTYSDIYNFPI.AFDKALEQQ..E..S...........
Retrocopy VEQREKRREEKALIAAQLDNAIEKELLERLKQDTYSDIYNFPIRAFDKALEQQEAESDSSDAEXXXXXXX

Parental  EEEVDETREFLEDDEVDESDIKLEDMDKLD-ISGSEDQDQRSSSEDEEKALDARHKGKTPLKGPLRRKRA
          ......TREF.EDDEVDESDI...D.......SG.EDQDQRSSSEDEEK.LDARHKGKTPLKGPLRRKRA
Retrocopy XXXXLGTREFAEDDEVDESDISDFDKLDIS>VSGNEDQDQRSSSEDEEKSLDARHKGKTPLKGPLRRKRA

Parental  YV
          YV
Retrocopy YV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_867 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 7 parental genes, and 13 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000009081	5 retrocopies	retro_chof_2336, retro_chof_2538, retro_chof_531, retro_chof_867 , retro_chof_948,
Dasypus novemcinctus	ENSDNOG00000008424	1 retrocopy	retro_dnov_624,
Latimeria chalumnae	ENSLACG00000018758	1 retrocopy	retro_lcha_67,
Macropus eugenii	ENSMEUG00000006945	1 retrocopy	retro_meug_1291,
Myotis lucifugus	ENSMLUG00000002758	1 retrocopy	retro_mluc_590,
Oryctolagus cuniculus	ENSOCUG00000008735	3 retrocopies	retro_ocun_1053, retro_ocun_1298, retro_ocun_908,
Sus scrofa	ENSSSCG00000015832	1 retrocopy	retro_sscr_917,