RetrogeneDB ID: retro_chof_2226

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_59725:8619..9431(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSCHOG00000000170
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: ARPC2
• Ensembl ID: ENSCHOG00000010564
• Aliases: None
• Description: actin related protein 2/3 complex, subunit 2, 34kDa [Source:HGNC Symbol;Acc:705]

Sequence

>retro_chof_2226
AAACCAGGAGCAACAGAAGCAGCGTTTGCAGATTTTCGTGGGGTCCTCTGCCGTATTTCAAATCCTAATGCAGACAAAAC
GAAAGTGATGGTCAGTATTTCTTTGAAATTCTACAAGGAACTTCAGGCACATGGTGCTGACAGTTATTAAAGACACGGTG
TACGGGAGTTTATTGGTAAATCCAGACTCAGGATACAATGTCTCTTTGCCATATGATGAAAATCTCCCTGCATCCAAGGA
TTCAATTGTGCATCAGGATAGCATGTTGAAAAGAAATTGTTTTGCCTCTGTCTTTGAGAAATACTTACAGCTCCAAGAAG
AGGGAAAGCAAGGAGAGAACAGGGCAGTTATCTATTACAGGAATGATGAGACCATGTATGTTGAGTCCAAAAAGAGAATC
ACAGTAGTCTTCAGCACAGTGTTTAAAAATGACGACGAAGTGTTTCTTGGAAAGGTGTTTATACAGGAATTCAAAGGACG
CAGAGCCAGCCCCATAGCCCCACAGGTCCTCTTCAGCCACGGGGATCCGCCTCTGGAGCTGAAAGACACAGATGCCGCTG
TGGGCGACAGCATTGGCTCTTATTACCTCCGTGCCGTTCCCTCGCCACCCCAAAGCCAGTGCCCAAGACAACACCATCAA
CTGATCGACAGGTTTCGGGACTACCTGCACCACCACATCAAGCGCTCTAAGGCCTGTATTCACACACGTATGCGGGCTAA
AAACATCTGACTTCCTAAAGGTGCTGAACCATGCACACCCGGATGCTGAGAAAATAGAAATGAAAAGAATCGTGGGGAAG
ACGTTTTCATCC

Alignment

ORF - retro_chof_2226 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.7 %
• Parental protein coverage: 91. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 4

Retrocopy - Parental Gene Alignment:

Parental  KPEAVEVTFADFDGVLYHISNPNGDKTKVMVSISLKFYKELQAHGADE-LLKRVYGSFLVNPESGYNVSL
          KP.A.E..FADF.GVL..ISNPN.DKTKVMVSISLKFYKELQAHGAD......VYGS.LVNP.SGYNVSL
Retrocopy KPGATEAAFADFRGVLCRISNPNADKTKVMVSISLKFYKELQAHGADS>IKDTVYGSLLVNPDSGYNVSL

Parental  LYDLENLPASKDSIVHQAGMLKRNCFASVFEKYFQFQEEGKEGENRAVIHYRDDETMYVESKKDRVTVVF
          .YD.ENLPASKDSIVHQ..MLKRNCFASVFEKY.Q.QEEGK.GENRAVI.YR.DETMYVESKK.R.TVVF
Retrocopy PYD-ENLPASKDSIVHQDSMLKRNCFASVFEKYLQLQEEGKQGENRAVIYYRNDETMYVESKK-RITVVF

Parental  STVFKDDDDVVIGKVFMQEFKEGRRASHTAPQVLFSHREPPLELKDTDAAVGDNIG-YITFVLVPRHTNA
          STVFK.DD.V..GKVF.QEFK.GRRAS..APQVLFSH..PPLELKDTDAAVGD.IG..IT.V..PRH..A
Retrocopy STVFKNDDEVFLGKVFIQEFK-GRRASPIAPQVLFSHGDPPLELKDTDAAVGDSIG>LITSVPFPRHPKA

Parental  GARDNTIN-LIHTFRDYLHYHIKCSKAYIHTRMRA-KTSDFLKVLNRARPDAEKKEMKTITGKTFSS
          .A.DNTIN.LI..FRDYLH.HIK.SKA.IHTRMRA.KTSDFLKVLN.A.PDAEK.EMK.I.GKTFSS
Retrocopy SAQDNTIN<LIDRFRDYLHHHIKRSKACIHTRMRA>KTSDFLKVLNHAHPDAEKIEMKRIVGKTFSS

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2226 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000003197	2 retrocopies	retro_amel_1771, retro_amel_1846,
Canis familiaris	ENSCAFG00000014618	1 retrocopy	retro_cfam_513,
Choloepus hoffmanni	ENSCHOG00000010564	5 retrocopies	retro_chof_1845, retro_chof_2103, retro_chof_2226 , retro_chof_2227, retro_chof_473,
Dasypus novemcinctus	ENSDNOG00000006037	1 retrocopy	retro_dnov_5,
Dipodomys ordii	ENSDORG00000016107	1 retrocopy	retro_dord_624,
Felis catus	ENSFCAG00000002370	1 retrocopy	retro_fcat_732,
Loxodonta africana	ENSLAFG00000007414	1 retrocopy	retro_lafr_593,
Myotis lucifugus	ENSMLUG00000004161	1 retrocopy	retro_mluc_390,
Mustela putorius furo	ENSMPUG00000016512	1 retrocopy	retro_mputfur_1294,
Mus musculus	ENSMUSG00000006304	1 retrocopy	retro_mmus_1556,
Oryctolagus cuniculus	ENSOCUG00000005516	1 retrocopy	retro_ocun_483,
Pteropus vampyrus	ENSPVAG00000017133	1 retrocopy	retro_pvam_1216,
Sorex araneus	ENSSARG00000003326	1 retrocopy	retro_sara_283,
Tarsius syrichta	ENSTSYG00000001037	1 retrocopy	retro_tsyr_557,