RetrogeneDB ID: retro_chof_2099

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_48884:7049..7475(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: AP1S3
• Ensembl ID: ENSCHOG00000011939
• Aliases: None
• Description: adaptor-related protein complex 1, sigma 3 subunit [Source:HGNC Symbol;Acc:18971]

Sequence

>retro_chof_2099
ATGCAGTTTATGTTGCTTTTTAGTCATCAGGGAAAGCTTCAAGCACAGAAGTGGTATGTCCCACTGTCAGACAAAGAGAA
GAAAAAGATCACACGGGAACTTGTTCAAACTGCTTTAGCAGGAGAACCTAAAGCGTGCAGCTTTCTTGAGTGGCAAGATC
TGAAGATTGTATACAAAAGATATGCCCATCTGTATCTTTGCTGTGCTCTTGAGGATCAGACAATGAACTAATTACCTTGG
AAATAATTCATCCTTACATGGAATTACTTGACAAGTATTTTGGCAGTGTGTGTGAACTTGATATCATCTTTAATTTTGAG
AAGGCTTATTTTATTTTGGATGAGTTCCTCTTGGGATGGGAAGTTCAGGAAACATCCAAGAAAAAATGTCCTCAAGGCCA
CTGAGCAGGCAGATCTCCTGCAGGAG

Alignment

ORF - retro_chof_2099 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 65.97 %
• Parental protein coverage: 100. %
• Number of stop codons detected: 0
• Number of frameshifts detected: 2

Retrocopy - Parental Gene Alignment:

Parental  IHFILLFSRQGKLRLQKWYTTLPDKERKKVTREIIQIILSRGQRTSSFVDWKELKLVYKRYASLYFCCAV
          ..F.LLFS.QGKL..QKWY..L.DKE.KK.TRE..Q..L.......SF..W..LK.VYKRYA.LY.CCA.
Retrocopy MQFMLLFSHQGKLQAQKWYVPLSDKEKKKITRELVQTALAGEPKACSFLEWQDLKIVYKRYAHLYLCCAL

Parental  ENQ-DNELLTLEIVHRYVELLDKYFGNVCELDIIFNFEKAYFILDEFIIGGEIQETSK-KSAVKAIEDSD
          E.Q.DNEL.TLEI.H.Y.ELLDKYFG.VCELDIIFNFEKAYFILDEF..G.E.QETSK.K...KA.E..D
Retrocopy EDQ<DNELITLEIIHPYMELLDKYFGSVCELDIIFNFEKAYFILDEFLLGWEVQETSK>KNVLKATEQAD

Parental  MLQE
          .LQE
Retrocopy LLQE

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_2099 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 10 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Choloepus hoffmanni	ENSCHOG00000011939	5 retrocopies	retro_chof_113, retro_chof_1230, retro_chof_1299, retro_chof_1949, retro_chof_2099 ,
Choloepus hoffmanni	ENSCHOG00000013301	4 retrocopies	retro_chof_2345, retro_chof_2677, retro_chof_393, retro_chof_820,
Callithrix jacchus	ENSCJAG00000012352	2 retrocopies	retro_cjac_3187, retro_cjac_3903,
Macropus eugenii	ENSMEUG00000016580	11 retrocopies	retro_meug_1074, retro_meug_1342, retro_meug_1488, retro_meug_168, retro_meug_1864, retro_meug_289, retro_meug_318, retro_meug_361, retro_meug_816, retro_meug_909, retro_meug_938,
Microcebus murinus	ENSMICG00000014406	1 retrocopy	retro_mmur_1492,
Monodelphis domestica	ENSMODG00000021198	1 retrocopy	retro_mdom_1427,
Mus musculus	ENSMUSG00000054702	3 retrocopies	retro_mmus_2202, retro_mmus_2799, retro_mmus_487,
Ochotona princeps	ENSOPRG00000013358	1 retrocopy	retro_opri_443,
Pan troglodytes	ENSPTRG00000012979	1 retrocopy	retro_ptro_2258,
Sarcophilus harrisii	ENSSHAG00000010973	1 retrocopy	retro_shar_695,