RetrogeneDB ID: retro_cfam_768

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 17:5892035..5892396(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: NAA20
• Ensembl ID: ENSCAFG00000032025
• Aliases: None
• Description: N(alpha)-acetyltransferase 20, NatB catalytic subunit [Source:HGNC Symbol;Acc:15908]

Sequence

>retro_cfam_768
ATGGGTAAAGTGGAAGATTCAGTAGCTAGGGAAGAATGGCACGGGCATGTCACAGCTCTCTCTGTTGCCCCCAGAATTTC
GACGCCTTGGTTTGGTTGCTAAACTTATGGAGTTATTAGAGGAGATTTCAGAAAGAAAGGGTGGATTTTTTTGTTGATCT
CCTTGTAAGAGTATCTAACCAAGTTGCAGTGAACATGTCCAAGCAGTTGGGCTACAGCATGTACAGGATAGTCATAGAGT
ACTACGCAAACGCAATGGGGAGCCCGACGAGGATGCCTATGATATGAGGAAAGCACTCTCCAGAGACACTGAGAAGAAAT
CCATCATACCTTTACCTCATCCTGTGAGGCCTGAAGACCTT

Alignment

ORF - retro_cfam_768 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 87.8 %
• Parental protein coverage: 63.83 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 3

Retrocopy - Parental Gene Alignment:

Parental  MGKAEGSVAREEWHGHVTALSVAP-EFRRLGLAAKLMELLEEISERKGGFF-VDLFVRVSNQVAVNMYKR
          MGK.E.SVAREEWHGHVTALSVAP.EFRRLGL.AKLMELLEEISERKGGFF.VDL.VRVSNQVAVNM.K.
Retrocopy MGKVEDSVAREEWHGHVTALSVAP>EFRRLGLVAKLMELLEEISERKGGFF>VDLLVRVSNQVAVNMSKQ

Parental  LGYSVYRTVIEYYSAS-NGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDI
          LGYS.YR.VIEYY....NGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPED.
Retrocopy LGYSMYRIVIEYYANA<NGEPDEDAYDMRKALSRDTEKKSIIPLPHPVRPEDL

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	59.26 RPM
SRP017611_brain	0.00 RPM	27.47 RPM
SRP017611_kidney	0.07 RPM	78.58 RPM
SRP017611_liver	0.00 RPM	17.55 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_768 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_768 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_768 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 21 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000001144	1 retrocopy	retro_btau_899,
Canis familiaris	ENSCAFG00000032025	1 retrocopy	retro_cfam_768 ,
Callithrix jacchus	ENSCJAG00000005377	4 retrocopies	retro_cjac_1099, retro_cjac_1629, retro_cjac_2984, retro_cjac_439,
Gorilla gorilla	ENSGGOG00000004247	1 retrocopy	retro_ggor_374,
Microcebus murinus	ENSMICG00000006044	1 retrocopy	retro_mmur_540,
Macaca mulatta	ENSMMUG00000007708	1 retrocopy	retro_mmul_479,
Mustela putorius furo	ENSMPUG00000001228	2 retrocopies	retro_mputfur_1495, retro_mputfur_321,
Mus musculus	ENSMUSG00000002728	3 retrocopies	retro_mmus_1228, retro_mmus_3146, retro_mmus_3257,
Nomascus leucogenys	ENSNLEG00000009855	1 retrocopy	retro_nleu_2267,
Oryctolagus cuniculus	ENSOCUG00000015481	1 retrocopy	retro_ocun_1331,
Otolemur garnettii	ENSOGAG00000011542	1 retrocopy	retro_ogar_2007,
Pongo abelii	ENSPPYG00000010746	1 retrocopy	retro_pabe_342,
Pan troglodytes	ENSPTRG00000013299	1 retrocopy	retro_ptro_284,
Ictidomys tridecemlineatus	ENSSTOG00000014733	1 retrocopy	retro_itri_1656,
Tupaia belangeri	ENSTBEG00000000969	1 retrocopy	retro_tbel_567,