RetrogeneDB ID: retro_cfam_752

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 17:21136865..21137358(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: None
• Ensembl ID: ENSCAFG00000010127
• Aliases: SNRPN, SNURF
• Description: Small nuclear ribonucleoprotein-associated protein [Source:UniProtKB/TrEMBL;Acc:E2RPQ0]

Sequence

>retro_cfam_752
CTGAGGGGGAACCTGGTCTTAATGACAGTAGAGGGATCTCCTCCCAAAGATACTGGCATTGCCTGAGTGGCACTTGCTGA
GCTGCCAGGGACTCAGGGATCAGCAGAGCTGCTGCACAGAAGTCCTAGCTAGTGTTCTAGTGCCCAGGATCCTGCAGGGC
TTGCTAGACCAGGCTGAGAGGTTGGTGGGCTATCCCAACAGGTGATGACCCCACAAAGAAGAGGCATTATTGCAGCTTCT
TCATCTGCTGCTACAGTCAGTACTGCAAGGGTCCCAACCCAGTATCCACCTAGCCATGGGGGTCCTCCCCCACCTAAGGG
CAAGGGCCCTTCCAGGCATGATGGGCCAGCCACTTGGCCTGAAGCCTCCATGGGTCGCCCAGTGGGGATCCCCCTGGGTG
AGCAACTCTAATGGGCATGTCCCCTCCAGGAATGCAGGGCTCTCCTCCTGGGAAGGGAGGGCCCCTCCCCTGGGAAAGCA
CTCACCAAGGCCC

Alignment

ORF - retro_cfam_752 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 58.52 %
• Parental protein coverage: 70.42 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 7

Retrocopy - Parental Gene Alignment:

Parental  LRGENLVSMTVEGPPPKDTGIARVPLAG-AAGGPGVGRAAGRG-VPAGVPIP-QAPAGLAGPVRGVGGPS
          LRG.NLV.MTVEG.PPKDTGIA.V.LA..AA...G..RAA....V.A.V..P.Q.PAGLA.P...VGG.S
Retrocopy LRG-NLVLMTVEGSPPKDTGIA*VALAE<AARDSGISRAAAQK<VLASVLVP<QDPAGLARPG*EVGGLS

Parental  QQVMTPQGRGTVAAAAVAATASIAGAPTQYPPGRGTPPTPVG-RATPPPGIMAPPPGMRPP-MGPPIGL-
          QQVMTPQ.RG..AA...AAT.S.A..PTQYPP..G.PP.P.G.RA.P..G.M..P.G..PP.MG.P.G..
Retrocopy QQVMTPQRRGIIAASSSAATVSTARVPTQYPPSHGGPPPPKG>RALP--GMMGQPLGLKPP<MGRPVGI<

Parental  PPARGTPIGMPPPGMRPPPPGIRGP-PPPGMRPPRP
          PP...T..GM.PPGM...PPG..GP.PP.G...PRP
Retrocopy PPG*ATLMGMSPPGMQGSPPGKGGP<PPLGKHSPRP

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	274.63 RPM
SRP017611_brain	0.00 RPM	300.58 RPM
SRP017611_kidney	0.00 RPM	99.58 RPM
SRP017611_liver	0.00 RPM	11.67 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_752 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_752 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_752 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 54 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000007034	3 retrocopies	retro_amel_1048, retro_amel_714, retro_amel_839,
Bos taurus	ENSBTAG00000008251	1 retrocopy	retro_btau_620,
Canis familiaris	ENSCAFG00000006693	3 retrocopies	retro_cfam_1268, retro_cfam_1773, retro_cfam_461,
Canis familiaris	ENSCAFG00000010127	6 retrocopies	retro_cfam_1753, retro_cfam_1874, retro_cfam_2039, retro_cfam_627, retro_cfam_682, retro_cfam_752 ,
Choloepus hoffmanni	ENSCHOG00000001846	2 retrocopies	retro_chof_2275, retro_chof_385,
Cavia porcellus	ENSCPOG00000020270	1 retrocopy	retro_cpor_878,
Felis catus	ENSFCAG00000022298	2 retrocopies	retro_fcat_1390, retro_fcat_1895,
Homo sapiens	ENSG00000128739	1 retrocopy	retro_hsap_2580,
Gorilla gorilla	ENSGGOG00000003988	1 retrocopy	retro_ggor_1615,
Loxodonta africana	ENSLAFG00000009458	1 retrocopy	retro_lafr_1012,
Myotis lucifugus	ENSMLUG00000023361	3 retrocopies	retro_mluc_1192, retro_mluc_1816, retro_mluc_2156,
Macaca mulatta	ENSMMUG00000023139	1 retrocopy	retro_mmul_644,
Mustela putorius furo	ENSMPUG00000014638	1 retrocopy	retro_mputfur_1080,
Mus musculus	ENSMUSG00000000948	3 retrocopies	retro_mmus_1285, retro_mmus_1733, retro_mmus_665,
Oryctolagus cuniculus	ENSOCUG00000003532	4 retrocopies	retro_ocun_1291, retro_ocun_488, retro_ocun_689, retro_ocun_846,
Otolemur garnettii	ENSOGAG00000007392	5 retrocopies	retro_ogar_1179, retro_ogar_3042, retro_ogar_3060, retro_ogar_475, retro_ogar_722,
Pongo abelii	ENSPPYG00000006269	1 retrocopy	retro_pabe_1900,
Pan troglodytes	ENSPTRG00000006826	1 retrocopy	retro_ptro_1507,
Rattus norvegicus	ENSRNOG00000015976	6 retrocopies	retro_rnor_1122, retro_rnor_1314, retro_rnor_1485, retro_rnor_2161, retro_rnor_2462, retro_rnor_2517,
Sus scrofa	ENSSSCG00000028124	2 retrocopies	retro_sscr_350, retro_sscr_405,
Ictidomys tridecemlineatus	ENSSTOG00000001339	1 retrocopy	retro_itri_44,
Tursiops truncatus	ENSTTRG00000010966	5 retrocopies	retro_ttru_1005, retro_ttru_1051, retro_ttru_1473, retro_ttru_580, retro_ttru_600,