RetrogeneDB ID: retro_cfam_1269

Retrocopy location

• Organism: Dog (Canis familiaris)
• Coordinates: 28:26409799..26410126(+)
• Located in intron of: ENSCAFG00000011725

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: FUNDC1
• Ensembl ID: ENSCAFG00000014506
• Aliases: None
• Description: FUN14 domain containing 1 [Source:HGNC Symbol;Acc:28746]

Sequence

>retro_cfam_1269
GAATCTTATAAAGTGTCGGATTTAACTGAGTATACGAGAAGACACTACTGGTGCAATCGAGTGCTTGGCTACAGTTCAGA
ATCTATGGTAGAAAAATTCTCAGTAGTCACCCTGATTGCAACGGGTGGAGTGACTGGCTGCCATGTAAGATTTTTGTTCC
AGAAGGTTGGAAAACTTGCATCAACCACGGTAGGTGGTGGCTTTCTTCTTCTTCAGATTGCCAGTCACAGCGGCTACCTG
CGAATTGACTGGAAGAGAGCTGAAAAAGATGTAAACAAAGCAAAAAGACAGATTAAGAAATGAGCAAATGATGCAGTACC
CAAAATA

Alignment

ORF - retro_cfam_1269 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 75.23 %
• Parental protein coverage: 70.32 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  ESYEVLDLTEYARRHHWWNRVFGHSSGPMVEKYSVATQIVMGGVTGWCAGFLFQKVGKLAATAVGGGFLL
          ESY.V.DLTEY.RRH.W.NRV.G.SS..MVEK.SV.T.I..GGVTG....FLFQKVGKLA.T.VGGGFLL
Retrocopy ESYKVSDLTEYTRRHYWCNRVLGYSSESMVEKFSVVTLIATGGVTGCHVRFLFQKVGKLASTTVGGGFLL

Parental  LQIASHSGYVQIDWKRVEKDVNKAKRQIKKRANKAAPEI
          LQIASHSGY..IDWKR.EKDVNKAKRQIKK.AN.A.P.I
Retrocopy LQIASHSGYLRIDWKRAEKDVNKAKRQIKK*ANDAVPKI

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP012049_cerebellum	0.00 RPM	12.60 RPM
SRP017611_brain	0.00 RPM	10.64 RPM
SRP017611_kidney	0.00 RPM	23.05 RPM
SRP017611_liver	0.00 RPM	2.10 RPM

ChIP-Seq

Canis familiaris was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_cfam_1269 retrocopy.

TSS

Canis familiaris was not studied using FANTOM5 data.

Lab

retro_cfam_1269 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_cfam_1269 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 19 parental genes, and 50 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000010258	3 retrocopies	retro_amel_586, retro_amel_644, retro_amel_825,
Bos taurus	ENSBTAG00000001637	4 retrocopies	retro_btau_1370, retro_btau_1591, retro_btau_305, retro_btau_587,
Canis familiaris	ENSCAFG00000014506	3 retrocopies	retro_cfam_1269 , retro_cfam_1675, retro_cfam_951,
Dasypus novemcinctus	ENSDNOG00000014551	2 retrocopies	retro_dnov_2091, retro_dnov_2240,
Equus caballus	ENSECAG00000022709	3 retrocopies	retro_ecab_210, retro_ecab_231, retro_ecab_567,
Echinops telfairi	ENSETEG00000012763	3 retrocopies	retro_etel_1614, retro_etel_697, retro_etel_852,
Felis catus	ENSFCAG00000005541	3 retrocopies	retro_fcat_1493, retro_fcat_179, retro_fcat_205,
Latimeria chalumnae	ENSLACG00000010215	1 retrocopy	retro_lcha_74,
Macropus eugenii	ENSMEUG00000006795	5 retrocopies	retro_meug_1597, retro_meug_2127, retro_meug_232, retro_meug_415, retro_meug_994,
Myotis lucifugus	ENSMLUG00000015860	3 retrocopies	retro_mluc_1032, retro_mluc_2302, retro_mluc_2304,
Macaca mulatta	ENSMMUG00000003505	1 retrocopy	retro_mmul_38,
Monodelphis domestica	ENSMODG00000021088	3 retrocopies	retro_mdom_1262, retro_mdom_769, retro_mdom_917,
Mustela putorius furo	ENSMPUG00000012924	1 retrocopy	retro_mputfur_209,
Oryctolagus cuniculus	ENSOCUG00000029753	5 retrocopies	retro_ocun_1008, retro_ocun_1376, retro_ocun_1567, retro_ocun_27, retro_ocun_314,
Pelodiscus sinensis	ENSPSIG00000013793	1 retrocopy	retro_psin_30,
Pteropus vampyrus	ENSPVAG00000009327	2 retrocopies	retro_pvam_1380, retro_pvam_232,
Sorex araneus	ENSSARG00000012878	4 retrocopies	retro_sara_276, retro_sara_367, retro_sara_494, retro_sara_551,
Sarcophilus harrisii	ENSSHAG00000000501	1 retrocopy	retro_shar_222,
Tursiops truncatus	ENSTTRG00000010466	2 retrocopies	retro_ttru_1099, retro_ttru_1735,