RetrogeneDB ID: retro_btau_1030

Retrocopy location

• Organism: Cow (Bos taurus)
• Coordinates: 23:32967832..32968319(-)
• Located in intron of: ENSBTAG00000021902

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: BT.92009
• Ensembl ID: ENSBTAG00000011025
• Aliases: None
• Description: Transcription factor BTF3 homolog 4 [Source:UniProtKB/Swiss-Prot;Acc:Q2KIY7]

Sequence

>retro_btau_1030
TTTACCAACAGCATGAATCAAGAAAAGTTAGCCAAACTTCAGGCTCAGGTCCGGATAGGGGGCAAGGGTACAGCTCGCAG
AAAGAAGAAGGTGGTACATAGAACAGCTACAAGCTGATGACAAAAAACTTCAGAGTTCTCTAAAAAAACTGGCTGTGAAT
AATATAGCTGGTATTGAAGAGGTGAACATGATTAAAGATGATGGGACAGTTATTCATTTCAACAATCCTAAAGTCCAAGC
TTCCCTTTCTGCCAACACCTTTGCAATTACCGGCCACGCAGAAGCCAAACCAATCACAGAAATGCTTCCTGGAATATTAA
GTTAGCTTGGTGCTGACAGCTTAACAAGTCTTAGGAAGTTAGCTGAACAGTTCCCTCGGCAAGTGCTGGATAGCAAAACC
CCAAAACCAGAAGACATTGATGAGGAGGAGGATGATGTTCCAGATCTCGTAGAAAATTTTGATGAGGCATCAAAGAATGA
AGCTAAC

Alignment

ORF - retro_btau_1030 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 98.77 %
• Parental protein coverage: 87.57 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  FTNSMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTAT-ADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGT
          FTNSMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTAT.ADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGT
Retrocopy FTNSMNQEKLAKLQAQVRIGGKGTARRKKKVVHRTAT>ADDKKLQSSLKKLAVNNIAGIEEVNMIKDDGT

Parental  VIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILSQLGADSLTSLRKLAEQFPRQVLDSKTPKPEDI
          VIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILS.LGADSLTSLRKLAEQFPRQVLDSKTPKPEDI
Retrocopy VIHFNNPKVQASLSANTFAITGHAEAKPITEMLPGILS*LGADSLTSLRKLAEQFPRQVLDSKTPKPEDI

Parental  DEEEDDVPDLVENFDEASKNEAN
          DEEEDDVPDLVENFDEASKNEAN
Retrocopy DEEEDDVPDLVENFDEASKNEAN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
ERP005899_liver	1.51 RPM	48.09 RPM
ERP005899_muscle	0.16 RPM	22.44 RPM
SRP017611_brain	0.32 RPM	21.29 RPM
SRP017611_kidney	0.47 RPM	24.95 RPM
SRP017611_liver	0.60 RPM	21.37 RPM
SRP030211_testis	0.42 RPM	61.83 RPM

ChIP-Seq

Bos taurus was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_btau_1030 retrocopy.

TSS

Bos taurus was not studied using FANTOM5 data.

Lab

retro_btau_1030 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_btau_1030 has 0 orthologous retrocopies within eutheria group .

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Parental genes homology:

Parental genes homology involve 22 parental genes, and 72 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000010012	5 retrocopies	retro_btau_1161, retro_btau_1344, retro_btau_1361, retro_btau_459, retro_btau_551,
Bos taurus	ENSBTAG00000011025	1 retrocopy	retro_btau_1030 ,
Canis familiaris	ENSCAFG00000003782	2 retrocopies	retro_cfam_2135, retro_cfam_938,
Callithrix jacchus	ENSCJAG00000021582	4 retrocopies	retro_cjac_2000, retro_cjac_2929, retro_cjac_4160, retro_cjac_451,
Cavia porcellus	ENSCPOG00000004006	1 retrocopy	retro_cpor_908,
Ciona savignyi	ENSCSAVG00000009653	1 retrocopy	retro_csav_25,
Dasypus novemcinctus	ENSDNOG00000003181	4 retrocopies	retro_dnov_1690, retro_dnov_1928, retro_dnov_2672, retro_dnov_921,
Echinops telfairi	ENSETEG00000011923	11 retrocopies	retro_etel_1017, retro_etel_1167, retro_etel_1207, retro_etel_1409, retro_etel_1990, retro_etel_2113, retro_etel_2203, retro_etel_291, retro_etel_663, retro_etel_804, retro_etel_953,
Loxodonta africana	ENSLAFG00000016124	3 retrocopies	retro_lafr_206, retro_lafr_769, retro_lafr_947,
Macropus eugenii	ENSMEUG00000006135	10 retrocopies	retro_meug_1114, retro_meug_1164, retro_meug_1333, retro_meug_1395, retro_meug_1512, retro_meug_1663, retro_meug_2008, retro_meug_298, retro_meug_903, retro_meug_966,
Myotis lucifugus	ENSMLUG00000016884	1 retrocopy	retro_mluc_912,
Macaca mulatta	ENSMMUG00000003636	1 retrocopy	retro_mmul_59,
Monodelphis domestica	ENSMODG00000000770	2 retrocopies	retro_mdom_33, retro_mdom_992,
Mustela putorius furo	ENSMPUG00000006966	2 retrocopies	retro_mputfur_1444, retro_mputfur_924,
Mus musculus	ENSMUSG00000028568	2 retrocopies	retro_mmus_1134, retro_mmus_2743,
Oryctolagus cuniculus	ENSOCUG00000001517	3 retrocopies	retro_ocun_1001, retro_ocun_1412, retro_ocun_1912,
Otolemur garnettii	ENSOGAG00000030256	2 retrocopies	retro_ogar_2759, retro_ogar_570,
Ochotona princeps	ENSOPRG00000013335	2 retrocopies	retro_opri_719, retro_opri_974,
Procavia capensis	ENSPCAG00000006428	3 retrocopies	retro_pcap_129, retro_pcap_307, retro_pcap_373,
Pongo abelii	ENSPPYG00000001353	2 retrocopies	retro_pabe_1850, retro_pabe_3010,
Rattus norvegicus	ENSRNOG00000008512	8 retrocopies	retro_rnor_1113, retro_rnor_1666, retro_rnor_1870, retro_rnor_1871, retro_rnor_1872, retro_rnor_537, retro_rnor_760, retro_rnor_998,
Sorex araneus	ENSSARG00000003173	2 retrocopies	retro_sara_680, retro_sara_690,