RetrogeneDB ID: retro_ptro_922

Retrocopy location

• Organism: Chimpanzee (Pan troglodytes)
• Coordinates: 14:59194534..59194846(+)
• Located in intron of: ENSPTRG00000006406

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: SCOC
• Ensembl ID: ENSPTRG00000016460
• Aliases: None
• Description: short coiled-coil protein [Source:HGNC Symbol;Acc:20335]

Sequence

>retro_ptro_922
CTCTCCCAGCACCTCAAACATTCATCAAGGATTTTGTATCCAAGGCCCAAAAGTTTGTTACCCAAGACGACAAATATTGA
CATGGATGCAGTTGATGCTGAAAATCATTTGGAAGTGGAGGGGAAAACACAGCTTATTAATCAAGTGTTGGAACCCCAAC
ATACACTTCAAGATCTCCCTGTCAGAGGAGATGCAGTTATGGAAGAAAATCTCAAGCTAAAATCAGAAAACCAAGTTCTT
AGACAATACACAGAAAATTTCATGTCAGCTTCTAGTGTTTTTCAAACAACTGACACAAAAAGCAAAAGAAAA

Alignment

ORF - retro_ptro_922 Open Reading Frame is conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 78.85 %
• Parental protein coverage: 85.25 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  LADDIDHSSRILYPRPKSLLPKMMNADMDAVDAENQVELEEKTRLINQVLELQHTLEDLSARVDAVKEEN
          L.....HSSRILYPRPKSLLPK..N.DMDAVDAEN..E.E.KT.LINQVLE.QHTL.DL..R.DAV.EEN
Retrocopy LSQHLKHSSRILYPRPKSLLPKTTNIDMDAVDAENHLEVEGKTQLINQVLEPQHTLQDLPVRGDAVMEEN

Parental  LKLKSENQVLGQYIENLMSASSVFQTTDTKSKRK
          LKLKSENQVL.QY.EN.MSASSVFQTTDTKSKRK
Retrocopy LKLKSENQVLRQYTENFMSASSVFQTTDTKSKRK

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.00 RPM	66.83 RPM
SRP007412_cerebellum	0.00 RPM	26.71 RPM
SRP007412_heart	0.12 RPM	24.83 RPM
SRP007412_kidney	0.16 RPM	32.79 RPM
SRP007412_liver	0.00 RPM	8.87 RPM
SRP007412_testis	0.00 RPM	22.24 RPM

ChIP-Seq

Pan troglodytes was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_ptro_922 retrocopy.

TSS

Pan troglodytes was not studied using FANTOM5 data.

Lab

retro_ptro_922 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ptro_922 has 5 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_1347
Gorilla gorilla	retro_ggor_1048
Pongo abelii	retro_pabe_1119
Macaca mulatta	retro_mmul_2186
Callithrix jacchus	retro_cjac_713

---

Parental genes homology:

Parental genes homology involve 23 parental genes, and 62 retrocopies.

Species	Parental gene accession	Retrocopies number
Ailuropoda melanoleuca	ENSAMEG00000010957	2 retrocopies	retro_amel_176, retro_amel_725,
Bos taurus	ENSBTAG00000022109	2 retrocopies	retro_btau_1843, retro_btau_1847,
Canis familiaris	ENSCAFG00000003699	2 retrocopies	retro_cfam_1564, retro_cfam_667,
Choloepus hoffmanni	ENSCHOG00000000604	10 retrocopies	retro_chof_1154, retro_chof_1651, retro_chof_1973, retro_chof_1980, retro_chof_2214, retro_chof_2394, retro_chof_2595, retro_chof_289, retro_chof_563, retro_chof_862,
Callithrix jacchus	ENSCJAG00000003060	2 retrocopies	retro_cjac_713, retro_cjac_95,
Dipodomys ordii	ENSDORG00000000177	8 retrocopies	retro_dord_359, retro_dord_461, retro_dord_476, retro_dord_578, retro_dord_634, retro_dord_639, retro_dord_712, retro_dord_724,
Erinaceus europaeus	ENSEEUG00000011107	1 retrocopy	retro_eeur_19,
Homo sapiens	ENSG00000153130	2 retrocopies	retro_hsap_1347, retro_hsap_228,
Gorilla gorilla	ENSGGOG00000028186	2 retrocopies	retro_ggor_1048, retro_ggor_291,
Macropus eugenii	ENSMEUG00000014534	2 retrocopies	retro_meug_1580, retro_meug_823,
Macaca mulatta	ENSMMUG00000022351	1 retrocopy	retro_mmul_2186,
Monodelphis domestica	ENSMODG00000025528	2 retrocopies	retro_mdom_1163, retro_mdom_1265,
Mustela putorius furo	ENSMPUG00000016119	2 retrocopies	retro_mputfur_468, retro_mputfur_708,
Nomascus leucogenys	ENSNLEG00000005081	2 retrocopies	retro_nleu_1830, retro_nleu_849,
Oryctolagus cuniculus	ENSOCUG00000006591	3 retrocopies	retro_ocun_1400, retro_ocun_1657, retro_ocun_429,
Otolemur garnettii	ENSOGAG00000026414	2 retrocopies	retro_ogar_2489, retro_ogar_3043,
Procavia capensis	ENSPCAG00000003165	2 retrocopies	retro_pcap_119, retro_pcap_457,
Pongo abelii	ENSPPYG00000015077	2 retrocopies	retro_pabe_1119, retro_pabe_423,
Pan troglodytes	ENSPTRG00000016460	2 retrocopies	retro_ptro_198, retro_ptro_922 ,
Sarcophilus harrisii	ENSSHAG00000003474	1 retrocopy	retro_shar_572,
Ictidomys tridecemlineatus	ENSSTOG00000028529	3 retrocopies	retro_itri_1170, retro_itri_357, retro_itri_451,
Tarsius syrichta	ENSTSYG00000011814	6 retrocopies	retro_tsyr_1232, retro_tsyr_1446, retro_tsyr_1566, retro_tsyr_2025, retro_tsyr_34, retro_tsyr_446,
Tursiops truncatus	ENSTTRG00000010677	1 retrocopy	retro_ttru_123,