RetrogeneDB ID: retro_mmul_596

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: 10:25838041..25838509(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: GINS2
• Ensembl ID: ENSMMUG00000020594
• Aliases: None
• Description: DNA replication complex GINS protein PSF2 [Source:UniProtKB/TrEMBL;Acc:F7BZU2]

Sequence

>retro_mmul_596
GGTGGGTACCTGGAGCCTTTTAACCGTGGTTTACCAGTGGAAGTGCCCCCGTGGCTGGCAATTAACCTGAAGCAAAGACA
CAAATGTTGACTGCTCCCTCCGGAGTGGATGGACGTAGGAAAGTTGGAGAAGATGAGGAATCATGAACGAAAGGAAGAAA
CTCTCACCCCAATGCCCGGCCCTTACTACATGGAACTTACCAAGCTCCTGTTAAATCATGCTTCAGACAACATCCCAAAG
GCAGATGAAATCTGGACCCTGGTCAAGGACATGTGGGACACTCGTATAGCCAAACTCCGAGTGTCTGCTGACAGCTTTGT
GAGACAACAGGAGGCACATGCCAAGCTGGATCACTTGACCTTGATGGAGATCAACACCAGCAGGACTGTCCTCACACAAG
CGCTCAGCCACATGTACAAACTCCGCACAAACCTCCAGCCTTCGGAGAGTACTCAGTCTCAGGACTTC

Alignment

ORF - retro_mmul_596 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 90.38 %
• Parental protein coverage: 84.32 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  GGDLGPFNPGLPVEVPLWLAINLKQRQKCRLLPPEWMDVEKLEKMRDHERKEETFTPMPSPYYMELTKLL
          GG.L.PFN.GLPVEVP.WLAINLKQR.KC.LLPPEWMDV.KLEKMR.HERKEET.TPMP.PYYMELTKLL
Retrocopy GGYLEPFNRGLPVEVPPWLAINLKQRHKC*LLPPEWMDVGKLEKMRNHERKEETLTPMPGPYYMELTKLL

Parental  LNHASDNIPKADEIRTLVKDMWDTRIAKLRVSADSFVRQQEAHAKLDNLTLMEINTSGTFLTQALNHMYK
          LNHASDNIPKADEI.TLVKDMWDTRIAKLRVSADSFVRQQEAHAKLD.LTLMEINTS.T.LTQAL.HMYK
Retrocopy LNHASDNIPKADEIWTLVKDMWDTRIAKLRVSADSFVRQQEAHAKLDHLTLMEINTSRTVLTQALSHMYK

Parental  LRTNLQPSESTQSQDF
          LRTNLQPSESTQSQDF
Retrocopy LRTNLQPSESTQSQDF

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	0.67 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	0.40 RPM
SRP007412_cerebellum	0.00 RPM	2.97 RPM
SRP007412_heart	0.00 RPM	1.35 RPM
SRP007412_kidney	0.00 RPM	1.06 RPM
SRP007412_liver	0.00 RPM	0.87 RPM
SRP007412_testis	0.08 RPM	11.61 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_596 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_596 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_596 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_2477
Pan troglodytes	retro_ptro_1433
Gorilla gorilla	retro_ggor_1542
Pongo abelii	retro_pabe_1826

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Parental genes homology:

Parental genes homology involve 14 parental genes, and 19 retrocopies.

Species	Parental gene accession	Retrocopies number
Callithrix jacchus	ENSCJAG00000017303	1 retrocopy	retro_cjac_3309,
Dasypus novemcinctus	ENSDNOG00000008760	4 retrocopies	retro_dnov_1034, retro_dnov_166, retro_dnov_2424, retro_dnov_604,
Homo sapiens	ENSG00000131153	1 retrocopy	retro_hsap_2477,
Gallus gallus	ENSGALG00000028131	1 retrocopy	retro_ggal_22,
Gorilla gorilla	ENSGGOG00000009069	2 retrocopies	retro_ggor_1542, retro_ggor_960,
Macropus eugenii	ENSMEUG00000014703	1 retrocopy	retro_meug_1479,
Microcebus murinus	ENSMICG00000016691	1 retrocopy	retro_mmur_342,
Macaca mulatta	ENSMMUG00000020594	1 retrocopy	retro_mmul_596 ,
Pongo abelii	ENSPPYG00000007616	2 retrocopies	retro_pabe_1826, retro_pabe_896,
Pan troglodytes	ENSPTRG00000008430	1 retrocopy	retro_ptro_1433,
Pteropus vampyrus	ENSPVAG00000004944	1 retrocopy	retro_pvam_762,
Sarcophilus harrisii	ENSSHAG00000015249	1 retrocopy	retro_shar_382,
Sus scrofa	ENSSSCG00000002663	1 retrocopy	retro_sscr_883,
Tupaia belangeri	ENSTBEG00000006220	1 retrocopy	retro_tbel_1328,