RetrogeneDB ID: retro_mmul_2525

Retrocopy location

• Organism: Rhesus macaque (Macaca mulatta)
• Coordinates: X:108572328..108572660(+)
• Located in intron of: None

Retrocopy information

• Ensembl ID: ENSMMUG00000023220
• Aliases: None
• Status: KNOWN_PSEUDOGENE

Parental gene information

• Parental gene symbol: MMU.3975
• Ensembl ID: ENSMMUG00000008729
• Aliases: None
• Description: 40S ribosomal protein S5 [Source:RefSeq peptide;Acc:NP_001252648]

Sequence

>retro_mmul_2525
CTTGTCAAGCATGCCTTCAAGATCATCCACCTGCTTACAGGCAAGAACCCTCTGCAGGTTCTGGTGAATGCCATCATCAA
AAGTGGCCCTGGGAGGACTCCACATACATCGAGCAAGCTGAGACTGTGAGACAGCAGGACGTGGACATGTCCCCACTGTG
CCATGTGAATCAAGCCATCTGGCTGCTGTACACAGGTGCCAGTGAGGCTGCCTTCCAGAATATCAAGACCGTCACTGAAT
ACCTGGCTGATAAGCTCATCAACACTGCCAAGAGCTCTTCCAACTCCTATGCCATTGAGAAGAAAAAGCTGGAGCTTATG
GCCAAGTCCAAC

Alignment

ORF - retro_mmul_2525 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.34 %
• Parental protein coverage: 54.9 %
• Number of stop codons detected: 0
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  IVKHAFEIIHLLTGENPLQVLVNAIINSGPR-EDSTRIGRAGTVRRQAVDVSPLRRVNQAIWLLCTGARE
          .VKHAF.IIHLLTG.NPLQVLVNAII.SGP..EDST.I..A.TVR.Q.VD.SPL..VNQAIWLL.TGA.E
Retrocopy LVKHAFKIIHLLTGKNPLQVLVNAIIKSGPG<EDSTYIEQAETVRQQDVDMSPLCHVNQAIWLLYTGASE

Parental  AAFRNIKTIAECLADELINAAKGSSNSYAIKKKDELERVAKSN
          AAF.NIKT..E.LAD.LIN.AK.SSNSYAI.KK..LE..AKSN
Retrocopy AAFQNIKTVTEYLADKLINTAKSSSNSYAIEKK-KLELMAKSN

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.00 RPM	48.63 RPM
SRP007412_brain_prefrontal_cortex	0.00 RPM	112.57 RPM
SRP007412_cerebellum	0.00 RPM	56.95 RPM
SRP007412_heart	0.00 RPM	101.93 RPM
SRP007412_kidney	0.00 RPM	140.96 RPM
SRP007412_liver	0.00 RPM	271.58 RPM
SRP007412_testis	0.00 RPM	78.74 RPM

ChIP-Seq

Macaca mulatta was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mmul_2525 retrocopy.

TSS

Macaca mulatta was not studied using FANTOM5 data.

Lab

retro_mmul_2525 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_mmul_2525 has 4 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Pan troglodytes	retro_ptro_3152
Gorilla gorilla	retro_ggor_2942
Pongo abelii	retro_pabe_3683
Callithrix jacchus	retro_cjac_4105

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Parental genes homology:

Parental genes homology involve 18 parental genes, and 49 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000002366	1 retrocopy	retro_cfam_1355,
Callithrix jacchus	ENSCJAG00000000304	6 retrocopies	retro_cjac_1463, retro_cjac_2049, retro_cjac_2050, retro_cjac_2508, retro_cjac_4105, retro_cjac_599,
Echinops telfairi	ENSETEG00000013543	1 retrocopy	retro_etel_912,
Homo sapiens	ENSG00000083845	5 retrocopies	retro_hsap_2524, retro_hsap_2526, retro_hsap_3649, retro_hsap_3976, retro_hsap_4224,
Gorilla gorilla	ENSGGOG00000004258	4 retrocopies	retro_ggor_1577, retro_ggor_2465, retro_ggor_2828, retro_ggor_2942,
Macropus eugenii	ENSMEUG00000015400	3 retrocopies	retro_meug_1075, retro_meug_1792, retro_meug_347,
Myotis lucifugus	ENSMLUG00000012641	1 retrocopy	retro_mluc_2266,
Macaca mulatta	ENSMMUG00000008729	3 retrocopies	retro_mmul_1595, retro_mmul_2525 , retro_mmul_77,
Mustela putorius furo	ENSMPUG00000008308	1 retrocopy	retro_mputfur_1316,
Ornithorhynchus anatinus	ENSOANG00000011921	1 retrocopy	retro_oana_83,
Otolemur garnettii	ENSOGAG00000013088	2 retrocopies	retro_ogar_1711, retro_ogar_3461,
Procavia capensis	ENSPCAG00000011034	2 retrocopies	retro_pcap_168, retro_pcap_58,
Pongo abelii	ENSPPYG00000010500	7 retrocopies	retro_pabe_1857, retro_pabe_1858, retro_pabe_2996, retro_pabe_3270, retro_pabe_3413, retro_pabe_3683, retro_pabe_375,
Pan troglodytes	ENSPTRG00000011591	6 retrocopies	retro_ptro_1469, retro_ptro_1471, retro_ptro_2474, retro_ptro_2700, retro_ptro_2868, retro_ptro_3152,
Ictidomys tridecemlineatus	ENSSTOG00000005935	1 retrocopy	retro_itri_1742,
Tupaia belangeri	ENSTBEG00000016955	2 retrocopies	retro_tbel_1127, retro_tbel_1169,
Tarsius syrichta	ENSTSYG00000000076	2 retrocopies	retro_tsyr_1258, retro_tsyr_1981,
Tursiops truncatus	ENSTTRG00000001991	1 retrocopy	retro_ttru_106,