RetrogeneDB ID: retro_mdom_532

Retrocopy location

• Organism: Opossum (Monodelphis domestica)
• Coordinates: 1:187177661..187177907(-)
• Located in intron of: ENSMODG00000001647

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CRIPT
• Ensembl ID: ENSMODG00000000973
• Aliases: None
• Description: cysteine-rich PDZ-binding protein [Source:HGNC Symbol;Acc:14312]

Sequence

>retro_mdom_532
AAAAATAGAACAAGAAACACTATAGAAAGTGATAGAAGGAAATTAAATGAAAACAAGTCTTTGTCTTAAAGGAAACCAAA
ATTTGGCTCATATGGAAAGAATAAATTCTCTACTTGCAGAATTTGTAAAAGTTCTGTGCATCAACCAGGTTCTCATTATT
GCCAAGGCTGTGCTTACAAAAAAGGCACCTGCTCAATGTGTGGGGAAAAGATTTTAAATACCAAGAACGACAAGTAAATA
TCTGTT

Alignment

ORF - retro_mdom_532 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 74.39 %
• Parental protein coverage: 81.19 %
• Number of stop codons detected: 2
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  KDGARNTTESGGRKLNENKALTSKKARFDPYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGICSMCGKK
          K...RNT.ES..RKLNENK.L...K..F..YGKNKFSTCRICKSSVHQPGSHYCQGCAYKKG.CSMCG.K
Retrocopy KNRTRNTIESDRRKLNENKSLS*RKPKFGSYGKNKFSTCRICKSSVHQPGSHYCQGCAYKKGTCSMCGEK

Parental  VLDTKNYKQTSV
          .L.TKN.K..SV
Retrocopy ILNTKNDK*ISV

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain	0.12 RPM	37.07 RPM
SRP007412_cerebellum	0.33 RPM	0.00 RPM
SRP007412_heart	0.00 RPM	0.00 RPM
SRP007412_kidney	0.00 RPM	0.00 RPM
SRP007412_liver	0.00 RPM	0.00 RPM
SRP007412_testis	0.20 RPM	46.16 RPM

ChIP-Seq

Monodelphis domestica was not studied using ChIP-Seq data.

EST

No EST(s) were mapped for retro_mdom_532 retrocopy.

TSS

Monodelphis domestica was not studied using FANTOM5 data.

Lab

retro_mdom_532 was not experimentally validated.

Homology

Retrocopy orthology:

Monodelphis domestica does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

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Parental genes homology:

Parental genes homology involve 15 parental genes, and 30 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000015723	2 retrocopies	retro_btau_315, retro_btau_523,
Canis familiaris	ENSCAFG00000002633	1 retrocopy	retro_cfam_1105,
Choloepus hoffmanni	ENSCHOG00000000556	7 retrocopies	retro_chof_1031, retro_chof_1059, retro_chof_1241, retro_chof_2093, retro_chof_235, retro_chof_634, retro_chof_956,
Cavia porcellus	ENSCPOG00000008081	1 retrocopy	retro_cpor_1128,
Dipodomys ordii	ENSDORG00000006085	1 retrocopy	retro_dord_788,
Equus caballus	ENSECAG00000012342	2 retrocopies	retro_ecab_310, retro_ecab_366,
Felis catus	ENSFCAG00000015610	1 retrocopy	retro_fcat_1369,
Microcebus murinus	ENSMICG00000009133	1 retrocopy	retro_mmur_30,
Myotis lucifugus	ENSMLUG00000004193	2 retrocopies	retro_mluc_1480, retro_mluc_2080,
Macaca mulatta	ENSMMUG00000005388	1 retrocopy	retro_mmul_1191,
Monodelphis domestica	ENSMODG00000000973	1 retrocopy	retro_mdom_532 ,
Otolemur garnettii	ENSOGAG00000008089	6 retrocopies	retro_ogar_1206, retro_ogar_1967, retro_ogar_2609, retro_ogar_2734, retro_ogar_3132, retro_ogar_984,
Rattus norvegicus	ENSRNOG00000015215	1 retrocopy	retro_rnor_2485,
Tarsius syrichta	ENSTSYG00000002853	2 retrocopies	retro_tsyr_1596, retro_tsyr_85,
Vicugna pacos	ENSVPAG00000000315	1 retrocopy	retro_vpac_417,