RetrogeneDB ID: retro_ggor_3048

Retrocopy location

• Organism: Gorilla (Gorilla gorilla)
• Coordinates: X:93061894..93062878(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: KAT7
• Ensembl ID: ENSGGOG00000007469
• Aliases: None
• Description: None

Sequence

>retro_ggor_3048
ATGGAACACAGACAGACCTATGGGAACACACGGGAACCTCTTTTAGAAAACTTGACAAGCGAGTAAGACTTGGATCTTTT
CCGAAGAGCACAAGCCCGGGCTTCAGAGGATTTGGAGAAGTTAAGTCTGCAAGGCCAAATCACAGAGGGAAGCAACATGA
TTAAAACAATTGCTTTTGGTCGCTATGACCTTGATACCTGGTACCATTCTCCATATCCTGAAGAATATGCACAGCTGGGA
CGTCTCTGTATGTGTGAATTCTGTTTAAAATATATGAAGAGCCAAATGATACTCCACCAGCACATGGCCAAATGTGTGTG
GAAACACCCACCTGGTGATGAGATATATCGCAAAGGTTCAATCTCTGTGTTTGAAGTGGATGGCAAGAAAAACAAGATCT
ACTGCCAAAACCTGTGCCTGCTGGCCAAACTTTTTCTGGACCACAAGACATTATATTATGATGTGGAGCCCTTCCTGTTC
TATGTTATGACAGAGGCGGACAACACTGGCTGTCACCTGATTGGATATTTTTCCAAGGAAAAGAATTCATTCCTCAACTA
CAACGTATCCTGTATCCTTACTATGCCTCAGTACATGAGACAGGGCTATGGCAAGATGCTTATTGATTTCAGTTATTTGC
TTTCCAAAGTTGAAGAAAAAGTTGGCTCCCCAGAATGTCCACTCTCAGATCTGGGGCTTATAAGCTATCGCAGTTATTGG
AAAGAAGTACTTCTCTGCTACCTGCGTAATTTCCAAGGCAAAGAGATTTCTATCAAAGAAATCAGTCAGGAGACGGCTGT
GAATCCTGTGGACATTGTTAGCACTCTGCAAGCCCTTCAGATGCTCAAGTACTGGAAGGGAAAACACCTAGTTTTAAAGA
GACAGGACCTGACTGATGAGTGGATAGCCAAAGAGGCCAAAAGGTCCAACTCCAATAAAACCATGGATCCCAGCTGCTTA
AAATGGACCCCTCCCAAGGGCACT

Alignment

ORF - retro_ggor_3048 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 96.34 %
• Parental protein coverage: 53.16 %
• Number of stop codons detected: 1
• Number of frameshifts detected: 0

Retrocopy - Parental Gene Alignment:

Parental  MEHRQTYGNTREPLLENLTSEYDLDLFRRAQARASEDLEKLRLQGQITEGSNMIKTIAFGRYELDTWYHS
          MEHRQTYGNTREPLLENLTSE.DLDLFRRAQARASEDLEKL.LQGQITEGSNMIKTIAFGRY.LDTWYHS
Retrocopy MEHRQTYGNTREPLLENLTSE*DLDLFRRAQARASEDLEKLSLQGQITEGSNMIKTIAFGRYDLDTWYHS

Parental  PYPEEYARLGRLYMCEFCLKYMKSQTILRRHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCL
          PYPEEYA.LGRL.MCEFCLKYMKSQ.IL..HMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCL
Retrocopy PYPEEYAQLGRLCMCEFCLKYMKSQMILHQHMAKCVWKHPPGDEIYRKGSISVFEVDGKKNKIYCQNLCL

Parental  LAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF
          LAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF
Retrocopy LAKLFLDHKTLYYDVEPFLFYVMTEADNTGCHLIGYFSKEKNSFLNYNVSCILTMPQYMRQGYGKMLIDF

Parental  SYLLSKVEEKVGSPERPLSDLGLISYRSYWKEVLLRYLHNFQGKEISIKEISQETAVNPVDIVSTLQALQ
          SYLLSKVEEKVGSPE.PLSDLGLISYRSYWKEVLL.YL.NFQGKEISIKEISQETAVNPVDIVSTLQALQ
Retrocopy SYLLSKVEEKVGSPECPLSDLGLISYRSYWKEVLLCYLRNFQGKEISIKEISQETAVNPVDIVSTLQALQ

Parental  MLKYWKGKHLVLKRQDLIDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
          MLKYWKGKHLVLKRQDL.DEWIAKEAKRSNSNKTMDPSCLKWTPPKGT
Retrocopy MLKYWKGKHLVLKRQDLTDEWIAKEAKRSNSNKTMDPSCLKWTPPKGT

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Expression validation based on RNA-Seq data:

Library	Retrocopy expression	Parental gene expression
SRP007412_brain_prefrontal_cortex	0.05 RPM	43.30 RPM
SRP007412_cerebellum	0.00 RPM	54.68 RPM
SRP007412_heart	0.00 RPM	11.63 RPM
SRP007412_kidney	0.00 RPM	27.89 RPM
SRP007412_liver	0.00 RPM	15.91 RPM
SRP007412_testis	0.10 RPM	186.07 RPM

ChIP-Seq

Gorilla gorilla was not studied using ChIP-Seq data.

EST

Gorilla gorilla was not studied using EST data.

TSS

Gorilla gorilla was not studied using FANTOM5 data.

Lab

retro_ggor_3048 was not experimentally validated.

Homology

Retrocopy orthology:

Retrocopy retro_ggor_3048 has 3 orthologous retrocopies within eutheria group .

Species	RetrogeneDB ID
Homo sapiens	retro_hsap_4878
Pan troglodytes	retro_ptro_3250
Pongo abelii	retro_pabe_3795

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Parental genes homology:

Parental genes homology involve 9 parental genes, and 10 retrocopies.

Species	Parental gene accession	Retrocopies number
Canis familiaris	ENSCAFG00000016955	1 retrocopy	retro_cfam_1246,
Callithrix jacchus	ENSCJAG00000007037	1 retrocopy	retro_cjac_4188,
Homo sapiens	ENSG00000136504	1 retrocopy	retro_hsap_4878,
Gorilla gorilla	ENSGGOG00000007469	1 retrocopy	retro_ggor_3048 ,
Nomascus leucogenys	ENSNLEG00000003201	1 retrocopy	retro_nleu_2557,
Oryctolagus cuniculus	ENSOCUG00000000668	1 retrocopy	retro_ocun_1427,
Pongo abelii	ENSPPYG00000008925	1 retrocopy	retro_pabe_3795,
Pan troglodytes	ENSPTRG00000009383	1 retrocopy	retro_ptro_3250,
Tursiops truncatus	ENSTTRG00000000472	2 retrocopies	retro_ttru_1724, retro_ttru_1928,