RetrogeneDB ID: retro_chof_1772

Retrocopy location

• Organism: Sloth (Choloepus hoffmanni)
• Coordinates: scaffold_38033:3228..3851(-)
• Located in intron of: None

Retrocopy information

• Ensembl ID: None
• Aliases: None
• Status: NOVEL

Parental gene information

• Parental gene symbol: CRYZ
• Ensembl ID: ENSCHOG00000005167
• Aliases: None
• Description: crystallin, zeta (quinone reductase) [Source:HGNC Symbol;Acc:2419]

Sequence

>retro_chof_1772
CATATTCGCTCTGATACTTAAAGCAGAAAACCAGTCTTACCTTATACTCCCAGCTCAGATGTGGCAGGGTATGTAACAGA
AGCTGTTGGATATAACGTATCTGCTTTCAAGAAAGGTGACAGAGTTTTCACAACCAGCACAATCTCTGGCTACACAGAGT
ATGCTGTTGCAGCAGATCACACTGTTTACCCACTGCCAGAAAAACTGGACTTGAAACAAGGAGCTGCCATCGGTATCCCG
TATTTTACTGCTTTTTGAGCTTTGCTCCACAGTGCCCGGGTGAAAGCTGAAGAAAGTATCTTGGTACATGGGGCTAGTGG
AGGAGTTGGACTGGCAGCATGCCAAATTGCTAGAGCTTAAAGGTTTTGGGCACAGCTGGTACTGAGGAGGGACAAAACAT
TGTTTTGCAAAATGGAGCCCATGAAGTATTTAATCACAGAGAAGATAATTACATTGATAAAATTAAGAAATCTGTTGGTG
ACAAAGGAATTGATGTGATTATTGAAATGTTAGCTAATGTAAATCTTAGTAACGATTTGAATTTTCTGGCATATGGAGGA
CGAGTAATAATTGTTGGCAGTAGAGGCCCTATTGAAATAAACCCACGGGACACCATGGAAAGG

Alignment

ORF - retro_chof_1772 Open Reading Frame is not conserved.

Retrocopy - Parental Gene Alignment summary:

• Percent Identity: 83.89 %
• Parental protein coverage: 82.94 %
• Number of stop codons detected: 3
• Number of frameshifts detected: 1

Retrocopy - Parental Gene Alignment:

Parental  YIRSGTYSRKPVLPYTPGSDVAG-VIEAVGYNVSAFKKGDRVFTTNTISGGYAEYAVAADHTVYPLPEKT
          .IRS.T.SRKPVLPYTP.SDVAG.V.EAVGYNVSAFKKGDRVFTT.TISG.Y.EYAVAADHTVYPLPEK.
Retrocopy HIRSDT*SRKPVLPYTPSSDVAGYVTEAVGYNVSAFKKGDRVFTTSTISG-YTEYAVAADHTVYPLPEKL

Parental  DFKQGAAIGIPYFTAYRALLHSARVKAGESILVHGASGGGLA-TCQIARAYGLKVLGTAGTEEGQNIVLQ
          D.KQGAAIGIPYFTA..ALLHSARVKA.ESILVHGAS.GG...T........LKVLGTAGTEEGQNIVLQ
Retrocopy DLKQGAAIGIPYFTAF*ALLHSARVKAEESILVHGAS-GGVG<TGSMPNC*SLKVLGTAGTEEGQNIVLQ

Parental  NGAHEVFNHREENYIDKIKKSVGEKGIDVIIEMLANVNLSNDLNLLSYGGRVIIVGSRGRIEVNPRDTMA
          NGAHEVFNHRE.NYIDKIKKSVG.KGIDVIIEMLANVNLSNDLN.L.YGGRVIIVGSRG.IE.NPRDTM.
Retrocopy NGAHEVFNHREDNYIDKIKKSVGDKGIDVIIEMLANVNLSNDLNFLAYGGRVIIVGSRGPIEINPRDTME

Parental  K
          .
Retrocopy R

Legend:

• *: Stop codon
• >: Forward frameshift by one nucleotide
• <: Reverse frameshift by one nucleotide

Expression

RNA-Seq

Choloepus hoffmanni was not studied using RNA-Seq expression data.

ChIP-Seq

Choloepus hoffmanni was not studied using ChIP-Seq data.

EST

Choloepus hoffmanni was not studied using EST data.

TSS

Choloepus hoffmanni was not studied using FANTOM5 data.

Lab

retro_chof_1772 was not experimentally validated.

Homology

Retrocopy orthology:

Choloepus hoffmanni does not belong to any of the species groups (eutheria, teleost or neognath), studied for retrocopy-based homology. For more information about studied groups, please go to help section.

---

Parental genes homology:

Parental genes homology involve 16 parental genes, and 23 retrocopies.

Species	Parental gene accession	Retrocopies number
Bos taurus	ENSBTAG00000003162	1 retrocopy	retro_btau_1433,
Canis familiaris	ENSCAFG00000020404	1 retrocopy	retro_cfam_870,
Choloepus hoffmanni	ENSCHOG00000005167	1 retrocopy	retro_chof_1772 ,
Felis catus	ENSFCAG00000030626	1 retrocopy	retro_fcat_1907,
Homo sapiens	ENSG00000116791	1 retrocopy	retro_hsap_3884,
Loxodonta africana	ENSLAFG00000011371	1 retrocopy	retro_lafr_527,
Macaca mulatta	ENSMMUG00000014593	2 retrocopies	retro_mmul_1026, retro_mmul_1728,
Mustela putorius furo	ENSMPUG00000010969	1 retrocopy	retro_mputfur_119,
Mus musculus	ENSMUSG00000028199	1 retrocopy	retro_mmus_1314,
Nomascus leucogenys	ENSNLEG00000009543	2 retrocopies	retro_nleu_1890, retro_nleu_3115,
Otolemur garnettii	ENSOGAG00000011586	1 retrocopy	retro_ogar_179,
Pongo abelii	ENSPPYG00000001235	2 retrocopies	retro_pabe_1909, retro_pabe_3165,
Pan troglodytes	ENSPTRG00000000865	1 retrocopy	retro_ptro_1598,
Tupaia belangeri	ENSTBEG00000016750	3 retrocopies	retro_tbel_1665, retro_tbel_2353, retro_tbel_3800,
Tarsius syrichta	ENSTSYG00000004193	2 retrocopies	retro_tsyr_1218, retro_tsyr_1884,
Tursiops truncatus	ENSTTRG00000010471	2 retrocopies	retro_ttru_555, retro_ttru_958,